| oxygenase | <enzyme> That catalyses the incorporation of the oxygen of molecular oxygen into organic substrates. Dioxygenases (oxygen transferases) catalyse introduction of both atoms of molecular oxygen, monoxygenases (mixed function oxygenases) introduce one atom, the other becomes reduced to water, so that these enzymes require a second substrate, acting as oxygen donor. Both types are used by bacteria in degradation of aromatic compounds. Dioxygenases all contain iron, for example tryp 2, 3 dioxygenase. Examples of mono oxygenases are the enzymes that hydroxylate proline and lysine of collagen, using ketoglutarate. (18 Nov 1997) |
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| emodinanthrone oxygenase | <enzyme> Internal monooxygenase from aspergillus terreus which converts emodinanthrone to emodin; does not require any foreign electron donor Registry number: EC 1.13.12.- Synonym: emodin anthrone oxygenase, emodin anthrone monooxygenase, emodinanthrone monooxygenase (26 Jun 1999) |
| tryptophan oxygenase | <enzyme> A protohemoprotein. Forms formylkynurenine from l-tryptophan and molecular oxygen. Chemical name: L-Tryptophan:oxygen 2,3-oxidoreductase (decyclizing) Registry number: EC 1.13.11.11 (12 Dec 1998) |
| 2,3-dihydroxybiphenyl oxygenase | <enzyme> Forms meta cleavage cpd 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate Registry number: EC 1.13.11.39 Synonym: 2,3-ohbp oxygenase, biphenyl-2,3-diol 1,2 dioxygenase, bphc gene product, 2,3-dihydroxy biphenyl dioxygenase, bphc protein, 2,3-dhbp 1,2-dioxygenase, ctbc gene product (26 Jun 1999) |
| 2,4,5-trichlorophenoxyacetic acid oxygenase | <enzyme> Converts the herbicide 2,4,5-t to 2,4,5-trichlorophenol; genbank u11420 Registry number: EC 1.13.99.- Synonym: 2,4,5-t oxygenase (26 Jun 1999) |
| lactate 2-mono-oxygenase | A flavoprotein oxidoreductase catalyzing oxidation (with O2) of l-lactate to acetate plus CO2 and water. Synonym: lactic acid oxidative decarboxylase. (05 Mar 2000) |
| 2-nitrophenol oxygenase | <enzyme> Requires NADPH; uses 1 molecule of oxygen to form catechol plus nitrite; broad substrate specificity for halogen- and alkyl-substituted ortho-nitrophenols Registry number: EC 1.14.13.- Synonym: o-nitrophenol oxygenase, 2-nitrophenol monooxygenase (26 Jun 1999) |
| 2-oxo-delta-(3)-4,5,5-trimethylcyclopentenylacetyl-CoA oxygenase | <enzyme> Specific for NADPH as electron donor; incorporates single molecule of oxygen Registry number: EC 1.14.13.- Synonym: otmcpa CoA oxygenase, 2-oxo-delta-(3)-4,5,5-trimethylcyclopentenylacetyl-coenzyme a oxygenase (26 Jun 1999) |
| 3-hydroxy-4-oxoquinoline oxygenase | <enzyme> Forms n-formylanthranilic acid + co2; 24 amino acids of n-terminal sequence given in first source Registry number: EC 1.13.12.- Synonym: 1h-3-hydroxy-4-oxoquinoline oxygenase, 3-oh-4-oxoquinoline oxygenase (26 Jun 1999) |
| 4-methyl-5-nitrocatechol oxygenase | <enzyme> Catalyses conversion of 4-methyl-5-nitrocatechol to 2-hydroxy-5-methylquinone; dntb isolated from burkholderia; genbank u68411 Registry number: EC 1.13.12.- Synonym: mnc oxygenase, dntb gene product (26 Jun 1999) |
| 5-pyridoxic acid oxygenase | <enzyme> From arthrobacter cr-7 grown on pyridoxine; forms alpha-hydroxymethyl-alpha'-(n-acetylaminomethylene)succinic acid; uses NADPH + fad; involved in vitamin b6 degradation Registry number: EC 1.4.12.- (26 Jun 1999) |
| acquired platelet function defect | <haematology> Platelet function can be affected by a number of different disease processes including polycythaemia vera, leukaemia, myelofibrosis, renal failure, multiple myeloma and some medications (for example penicillins, salicylates, phenothiazines). Disturbed blood clotting can be manifested by: easy bruising, bleeding gums, nosebleeds, abnormal vaginal bleeding, rectal bleeding, skin rash, vomiting blood, coughing up blood or blood in the urine. A measure of bleeding time and coagulation profile will be part of the evaluation. (29 Dec 1997) |
| allomeric function | The combined function of the several segments of the spinal cord and medulla, communicating with each other by means of the white matter. (05 Mar 2000) |
| aperture function | <microscopy> In a diffraction-limited optical system, the function that determines the relationship between the image and each point in the object. Modifying the aperture function changes the image according to the modified Fourier-filtering (or optical filtration) property of the aperture. (05 Aug 1998) |
| arousal function | The ability of a sensory event to arouse the cortex to vigilance or readiness. (05 Mar 2000) |