| Lr | lawrencium; Limes reacting dose of diphtheria toxin |
|---|---|
| CD | cadaver donor; canine distemper; canine dose; carbohydrate dehydratase; carbon dioxide; cardiac dise... |
| LD | labor and delivery; laboratory data; labyrinthine defect; lactate dehydrogenase; laser Doppler; lear... |
| MD | Doctor of Medicine [Lat. Medicinae Doctor]; magnesium deficiency; main duct; maintenance dose; major... |
| MID | maximum inhibiting dilution; mesioincisodistal; midinfarct dementia; minimum infective dose; minimum... |
| minimal anaesthetic concentration | The end-alveolar concentration of an inhalation anaesthetic which prevents somatic response to a painful stimulus in 50% of individuals; an index of relative potency of inhalation anaesthetics. Synonym: minimal anaesthetic concentration. (05 Mar 2000) |
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| minimal brain dysfunction | An inability to control behaviour due to difficulty in processing neural stimuli. (12 Dec 1998) |
| minimal-change disease | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| minimal-change nephrotic syndrome | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| minimal deviation melanoma | <dermatology, tumour> A malignant melanoma showing less cytologic atypia than is usual in melanoma cells showing asymmetric expansile invasion of the dermis. (05 Mar 2000) |
| minimal inhibitory concentration | <microbiology, pharmacology> The lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro. (05 Mar 2000) |
| minimal medium | <cell culture> The simplest tissue culture medium that will support the proliferation of normal cells. (18 Nov 1997) |
| absorbed dose | The amount of energy absorbed per unit mass of irradiated material at the target site; in radiation therapy, the former unit for absorbed dose is the rad; the current (S.I.) unit is the gray. (05 Mar 2000) |
| air dose | The radiation dose, expressed in roentgens, delivered at a point in free air. Synonym: air dose. (05 Mar 2000) |
| bone marrow dose | The cumulative dose to the blood-forming organ from therapeutic or nuclear fallout irradiation; the presumed leukemogenic dose. (05 Mar 2000) |
| booster dose | A dose given at some time after an initial dose to enhance the effect, said usually of antigens for the production of antibodies. (05 Mar 2000) |
| breast dose in mammography | <radiology> 180 mrad / view -- mid-breast dose, guideline: less than 1 rad for 2-view exam (12 Dec 1998) |
| maintenance dose | In chemotherapy, systematic dosage at a level that maintains protection against exacerbation. (05 Mar 2000) |
| genetically significant dose | <physics, radiobiology> The genetically significant dose is that which, if received by every member of the population, would be expected to produce the same genetic injury to the population as do the actual doses received by the individuals irradiated. Thus, the genetically significant dose is the dose equivalent to the gonads weighted for the age and sex distribution in those members of the irradiated population expected to have offspring. The genetically significant dose is expressed in sieverts (or rem). Acronym: GSD (06 Aug 1998) |
| maximal dose | <pharmacology> The largest amount of a drug or physical procedure that an adult can take with safety. (05 Mar 2000) |
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