| TCID | tissue culture infective dose; tissue culture inoculated dose |
|---|---|
| TD | tabes dorsalis; tardive dyskinesia; T-cell dependent; temporary disability; terminal device; tetanus... |
| MLD | manual lymph drainage; median lethal dose; metachromatic leukodystrophy; minimal lesion disease; min... |
| CID | cellular immunodeficiency; charge injection device; chick infective dose; combined immunodeficiency ... |
| DIM | divalent ion metabolism; medium infective dose [Lat. dosis infectionis media] |
| minimal | Smallest or least, the smallest possible. Origin: L. Minimus = least (18 Nov 1997) |
|---|---|
| minimal air | The volume of gas that remains in the lungs and cannot be expelled after they have been removed from the body, or after the chest has been opened. (05 Mar 2000) |
| minimal alveolar concentration | The end-alveolar concentration of an inhalation anaesthetic which prevents somatic response to a painful stimulus in 50% of individuals; an index of relative potency of inhalation anaesthetics. Synonym: minimal anaesthetic concentration. (05 Mar 2000) |
| minimal amplitude nystagmus | Nystagmus of so small an amplitude that it is not detected by the usual clinical tests. Synonym: minimal amplitude nystagmus. Origin: micro-+ G. Nystagmos, a nodding (05 Mar 2000) |
| minimal anaesthetic concentration | The end-alveolar concentration of an inhalation anaesthetic which prevents somatic response to a painful stimulus in 50% of individuals; an index of relative potency of inhalation anaesthetics. Synonym: minimal anaesthetic concentration. (05 Mar 2000) |
| minimal brain dysfunction | An inability to control behaviour due to difficulty in processing neural stimuli. (12 Dec 1998) |
| minimal-change disease | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| minimal-change nephrotic syndrome | <nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome, minimal glomerular changes, in children affecting 2 to 3 children per 100,000 population under age 16 in the USA. Minimal change disease is also seen rarely in adults. The cause is unknown but may be related to an autoimmune illness. It is marked by oedema, albuminuria, and an increase in cholesterol in the blood, but otherwise with fairly good renal function. Tubular epithelium is vacuolated by cholesterol droplets, but the glomeruli show only that the foot processes of the glomerular epithelial cells are fused, probably secondary to the proteinuria; the cause of the increased glomerular permeability to plasma protein is unknown. Risk factors include a history for a immune disorder, recent immunisation or a bee sting. Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented. Synonym: lipoid nephrosis (27 Sep 1997) |
| minimal deviation melanoma | <dermatology, tumour> A malignant melanoma showing less cytologic atypia than is usual in melanoma cells showing asymmetric expansile invasion of the dermis. (05 Mar 2000) |
| minimal inhibitory concentration | <microbiology, pharmacology> The lowest concentration of antibiotic sufficient to inhibit bacterial growth when tested in vitro. (05 Mar 2000) |
| minimal medium | <cell culture> The simplest tissue culture medium that will support the proliferation of normal cells. (18 Nov 1997) |
| absorbed dose | The amount of energy absorbed per unit mass of irradiated material at the target site; in radiation therapy, the former unit for absorbed dose is the rad; the current (S.I.) unit is the gray. (05 Mar 2000) |
| air dose | The radiation dose, expressed in roentgens, delivered at a point in free air. Synonym: air dose. (05 Mar 2000) |
| bone marrow dose | The cumulative dose to the blood-forming organ from therapeutic or nuclear fallout irradiation; the presumed leukemogenic dose. (05 Mar 2000) |
| booster dose | A dose given at some time after an initial dose to enhance the effect, said usually of antigens for the production of antibodies. (05 Mar 2000) |