| mice minute virus | The type species of parvovirus prevalent in mouse colonies and found as a contaminant of many transplanted tumours or leukaemias. (12 Dec 1998) |
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| mice, mutant strains | Mice bearing mutant genes which are phenotypically expressed in the animals. (12 Dec 1998) |
| mice, neurologic mutants | Mice which carry mutant genes for neurologic defects or abnormalities. (12 Dec 1998) |
| mice, nude | Mutant mice homozygous for the recessive gene "nude" which fail to develop a thymus. They are useful in tumour studies and studies on immune responses. (12 Dec 1998) |
| mice, obese | Mutant mice exhibiting a marked obesity coupled with overeating, hyperglycaemia, hyperinsulinaemia, marked insulin resistance, and infertility when in a homozygous state. They may be inbred or hybrid. (12 Dec 1998) |
| mice, quaking | Mice homozygous for the mutant autosomal recessive gene, quaking (qk), associated with disorder in myelin formation and manifested by axial tremors. (12 Dec 1998) |
| mice, transgenic | Laboratory mice that have been produced from a genetically manipulated egg or embryo. The technique involves microinjection of foreign DNA fragments into the nucleus of the fertilised egg and transferring it into the uterus of a foster mother mouse. The inserted gene becomes integrated into every cell and tissue of the developing mouse, including its germ line cells. (12 Dec 1998) |
| pneumonia virus of mice | An RNA virus of the genus Pneumovirus, a member of the family Paramyxoviridae, occurring normally as latent infection in laboratory mice, but capable of activation by serial intranasal passage and causing pneumonia. Synonym: PVM virus. (05 Mar 2000) |
| severe combined immunodeficient mice | Mice that lack both T and B lymphocytes and are used for transplantation and study of human lymphoid tissues resulting in a SCID-human mouse chimera. See: severe combined immunodeficiency. (05 Mar 2000) |
| New Zealand mice | Inbred strains of mice, either black (NZB) or white (NZW), unique among strains used in experimental immunology because of their proclivity to spontaneous immunologic abnormalities and disorders including systemic lupus erythematosus similar to that found in humans. (05 Mar 2000) |
| NOD mice | Nonobese diabetic mice. Have unique histocompatibility antigens, pancreatic beta cells are destroyed by an autoimmune response. (14 Oct 1997) |
| nude mice | Strains of athymic mice bearing the recessive allele nu/nu which are largely hairless and lack all or most of the T-cell population. Show no rejection of either allografts or xenografts. Nu/nu alleles on some backgrounds have near normal numbers of T-cells. (18 Nov 1997) |
| transgenic mice | Mice that have a piece of foreign lincor DNA integrated into their genome. (05 Mar 2000) |
| joint mice | <radiology> Ossicles within joint space, seen in synovial osteochondromatosis (12 Dec 1998) |