| metachromatic g. |
a granular cell inclusion that stains a color different from that of the dye used. In certain bacteria, yeasts, yeastlike fungi, and protozoa, metachromatic granules appear red when stained with a blue dye. They are composed of complex polyphosphate, lipid, and nucleoprotein molecules (volutin) and serve as an intracellular phosphate reserve. Called also Babès-Ernst body or granule.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| metachromatic l. |
an autosomal recessive disorder due to deficiency of cerebroside sulfatase or sphingolipid activator protein1, characterized by accumulation of sulfatide in neural and nonneural tissues, with a diffuse loss of myelin in the central nervous system. There are three forms due to deficiency of cerebroside sulfatase, with variable age of onset, all initially presenting as mental regression and motor disturbances. The infantile form usually begins in the second year of life and is additionally characterized by developmental delay, seizures, optic atrophy, ataxia, weakness, loss of speech, and progressive spastic quadriparesis. The juvenile form is clinically similar, but presents between the ages of 4 and 12 and progresses more slowly; a variant of the juvenile form is caused by deficiency of sphingolipid activator protein1. The adult form begins after 16 years of age, generally presenting initially as dementia and disturbances in behavior and progressing more slowly to motor and posture disturbances. Called also sulfatide lipidosis.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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| metachromatic s. |
one that colors certain cell constituents a color different from that of the stain itself.
Ãâó: www.mercksource.com/pp/us/cns/cns_health_library.j...
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