| melanotic whitlow | <tumour> A melanoma beginning in the skin at the border of or beneath the nail. Synonym: melanotic whitlow. (05 Mar 2000) |
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| primitive neuroectodermal tumour | A designation used to refer to a group of morphologically similar embryonal neoplasms that arise in intracranial and peripheral sites of the nervous system and which may show various degrees of cellular differentiation; includes medulloblastoma, pineoblastoma, etc. (05 Mar 2000) |
| primitive neuroectodermal tumours | A type of brain tumour. Prenatal diagnosis: diagnosis before birth. Methods for prenatal diagnosis include ultrasound (of the uterus, placenta and developing foetus), chorionic villus sampling to obtain tissue for chromosome or biochemical analysis, amniocentesis to obtain amniotic fluid for the analysis of chromosmes, enzymes, DNA, etc. A growing number of birth defects and diseases are now amenable to prenatal diagnosis. Also called antenatal diagnosis. (12 Dec 1998) |
| hutchinson's melanotic freckle | A cutaneous malignant melanoma found most often on the sun-exposed areas of the skin, especially the face, which begins as a circumscribed, macular patch of mottled pigmentation, showing shades of dark brown, tan, or black, and enlarges by lateral growth before dermal invasion occurs. This type is the slowest growing, has the least tendency to metastasize, and seems to be the least aggressive form of malignant melanoma. Patients are commonly in their sixth or seventh decade. (12 Dec 1998) |
| neuroectodermal | Relating to the neuroectoderm. (05 Mar 2000) |
| neuroectodermal junction | The margin of the embryonic neural plate separating it from the embryonic ectoderm; cells from this region form the neural crest. Synonym: neurosomatic junction. (05 Mar 2000) |
| neuroectodermal tumour, peripheral | A heterogeneous group of malignant neoplasms arising in either supportive structures or neuronal tissue. They occur in adolescents and young adults. This tumour shares a number of characteristics with ewing's sarcoma: it is highly cellular and consists of a monotonous pattern of primitive-appearing round cells. The chest wall is the most common site but the trunk, abdomen, and pelvis are other primary sites. (12 Dec 1998) |
| neuroectodermal tumour, primitive | A malignant brain tumour sharing common features and biologic properties with medulloblastoma. Some pathologists and clinicians use the terms interchangeably: they both can disseminate throughout the nervous system and, in some cases, systemically. most lesions arise from the posterior fossa in children under five years of age. The tumour often produces hydrocephalus and symptoms of increased intracranial pressure. Papilledema is often present. (12 Dec 1998) |
| neuroectodermal tumours | Malignant neoplasms arising in the neuroectoderm, the portion of the ectoderm of the early embryo that gives rise to the central and peripheral nervous systems, including some glial cells. (12 Dec 1998) |