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"melanocyte stimulating hormone"¿¡ ´ëÇÑ °Ë»ö °á°úÀÔ´Ï´Ù. °Ë»ö °á°ú º¸´Â µµÁß¿¡ Tab ۸¦ ´©¸£½Ã¸é °Ë»ö âÀÌ ¼±Åõ˴ϴÙ.
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¿µ¹® luteinizing hormone(LH) ÇÑ±Û È²Ã¼Çü¼ºÈ£¸£¸ó
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  ¿©¼ºÀÇ ¿ù°æÀº Á¤ÇØÁø ¼ø¼­¿¡ ÀÇÇØ ÀϾ°Ô µÈ´Ù. ¸ÕÀú ³­Æ÷ÀÚ±ØÈ£¸£¸óÀÌ ³ú¿¡¼­ ºÐºñµÇ¾î ¿©¼ºÀÇ ³­¼Ò¸¦ ÀÚ±ØÇϰԠµÇ¸é ³­Æ÷°¡ Àڱع޾Ơ³­Æ÷È£¸£¸ó(¿¡½ºÆ®·ÎÁ¨)À» ºÐºñÇϰԠµÇ°í À̰ÍÀº ´Ù½Ã µÇ¸ÔÀ̱⠸ÞÄ¿´ÏÁò ÀÇÇØ ³ú¿¡ ÀÛ¿ëÀ» ÇÏ¿© È²Ã¼È­È£¸£¸óÀÌ ³ú¿¡¼­ ºÐºñµÇ°í À̰ÍÀÌ À̸¥¹Ù ÀýÁ¤¿¡ À̸£·¶À» ¶§, ³­Æ÷¿¡¼­ ¹è¶õÀÌ ÀϾ°Ô µÈ´Ù. ÀÌÈÄ ³­Æ÷´Â È²Ã¼·Î º¯ÇϰԠµÇ¸ç, ¹è¶õµÈ ³­ÀÚ°¡ ¼öÁ¤µÇÁö ¾Æ´ÏÇϸé, È²Ã¼´Â È²Ã¼È£¸£¸ó(ÇÁ·Î°Ô½ºÅ×·Ð)À» ºÐºñÇÑ µÚ ÅðÈ­µÇ°í °ð À̾ù°æÀÌ ÀϾ°Ô µÈ´Ù. ÀÌ ÀÏÀº Á¤»óÀûÀΠ´ëºÎºÐÀÇ ¿©¼º¿¡¼­ 28ÀÏÀ» ÁÖ±â·Î ÀϾ¸ç, ´ë°³ È²Ã¼È­È£¸£¸ó ÀýÁ¤ ÀÌÈÄ ¸¶Áö¸·Àº 14ÀϷΠÀÏÁ¤ÇÏ´Ù°í ÇÑ´Ù.
´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • adrenocorticotropic hormone
    ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó, ºÎ½ÅÇÇÁúÀÚ±ØÈ£¸£¸ó
  • adrenomedullary hormone
    ºÎ½Å¼ÓÁúÈ£¸£¸ó, ºÎ½Å¼öÁúÈ£¸£¸ó
  • androgenic hormone
    ³²¼º(È­)È£¸£¸ó
  • corticosteroid hormone
    ÄÚ¸£Æ¼ÄÚ½ºÅ×·ÎÀ̵åÈ£¸£¸ó
  • corticotropin-releasing hormone
    ÄÚ¸£Æ¼ÄÚÆ®·ÎÇɺкñÈ£¸£¸ó
  • diabetogenic hormone
    ´ç´¢º´¹ß»ýÈ£¸£¸ó
  • ectopic hormone
    µý°÷È£¸£¸ó, À̼ҼºÈ£¸£¸ó
  • estrogenic hormone
    ¿¡½ºÆ®·Î°Õ
  • female hormone
    ¿©¼ºÈ£¸£¸ó
  • gonadotropic hormone
    »ý½Ä»ùÀÚ±ØÈ£¸£¸ó, »ý½Ä¼±ÀÚ±ØÈ£¸£¸ó
  • gonadotropin-releasing hormone
    »ý½Ä»ùÀÚ±ØÈ£¸£¸óºÐºñÈ£¸£¸ó, »ý½Ä¼±ÀÚ±ØÈ£¸£¸óºÐºñÈ£¸£¸ó
  • gonadotropin-releasing hormone agonist
    »ý½Ä»ùÀÚ±ØÈ£¸£¸ó¹æÃâÈ£¸£¸óÀÛ¿ëÁ¦
  • growth hormone
    ¼ºÀåÈ£¸£¸ó
  • hypophysiotropic hormone
    ³úÇϼöüÀÚ±ØÈ£¸£¸ó
  • hypothalamic inhibitory hormone
    ½Ã»óÇϺξïÁ¦È£¸£¸ó
¿¾ ´ëÇÑÀÇÇù ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • adrenocortical hormone
    ºÎ½Å°ÑÁúÈ£¸£¸ó
  • adrenocorticotropic hormone
    ºÎ½Å°ÑÁúÀÚ±ØÈ£¸£¸ó
  • adrenomedullary hormone
    ºÎ½Å¼ÓÁúÈ£¸£¸ó
  • androgenic hormone
    ³²¼ºÈ£¸£¸ó
  • antidiuretic hormone
    Ç×ÀÌ´¢È£¸£¸ó
  • hormone bombardment
    È£¸£¸óÃæ°Ý¿ä¹ý
  • corticosteroid hormone
    ÄÚ¸£Æ¼ÄÚ½ºÅ×·ÎÀ̵åÈ£¸£¸ó
  • corticotropin-releasing hormone
    ÄÚ¸£Æ¼ÄÚÆ®·ÎÇɺкñÈ£¸£¸ó
  • diabetogenic hormone
    ´ç´¢º´¹ß»ýÈ£¸£¸ó
  • digestive hormone
    ¼ÒÈ­È£¸£¸ó
  • hormone dependent
    È£¸£¸óÀÇÁ¸
  • thyroid hormone deficiency
    ¹æÆÐ»ùÈ£¸£¸ó°áÇÌ, °©»ó»ùÈ£¸£¸ó°áÇÌ
  • ectopic hormone
    µý°÷È£¸£¸ó
  • embryonic hormone
    ¹è¾ÆÈ£¸£¸ó
  • estrogenic hormone
    ¿¡½ºÆ®·Î°Õ
¿¾ ´ëÇÑÀÇÇù 2 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • adrenal cortical hormone =adrenocortical hormone
    ºÎ½ÅÇÇÁúÈ£¸£¸ó
  • B cell stimulating factor (BSF)
    B¼¼Æ÷ ÀÚ±ØÀÎÀÚ
  • G-CSF (Granulocyte colony-stimulating factor)
    °ú¸³¼¼Æ÷±ºÃËÁøÀÎÀÚ(Î¨Ø£á¬øàÏØõµòäì×í­)
  • Macrophage colony-stimulating factor
    ´ë½Ä¼¼Æ÷Áý¶ôÇü¼ºÃËÁøÀÎÀÚ(ÓÞãÝá¬øàó¢Õªû¡à÷õµòäì×í­)à÷õµòäì×?
  • adrenergic stimulating drug
    ¾Æµå·¹³¯¸°ÈïºÐ¾à, ¾Æµå·¹³¯¸°ÀÚ±ØÁ¦.
  • appetite stimulating agent
    ½Ä¿åÃËÁø¾à(¡­õµòäå·).
  • appetite stimulating agent
    ½Ä¿åÀÚ±ØÁ¦
  • ganglionic stimulant =g. stimulating agent
    ½Å°æÀýÈïºÐ¾à(¡­ýéÝÇå·).
  • granulocyte colony-stimulating factor
    °ú¸³±¸Áý¶ôÀÚ±ØÀÎÀÚ
  • granulocyte colony-stimulating factor=G-CSF
    °ú¸³±¸Áý¶ôÀÚ±ØÀÎÀÚ
  • granulocyte-macrophage colony- stimulating factor
    °ú¸³±¸´ë½Ä¼¼Æ÷Áý¶ôÀÚ±ØÀÎÀÚ
  • granulocyte-macrophage colony-stimulating factor=GM-CSF
    °ú¸³±¸-´ë½Ä¼¼Æ÷Áý¶ôÀÚ±ØÀÎÀÚ
  • ACTH=£¾adrenocorticotropic hormone
    ºÎ½ÅÇÇÁúÀÚ±ØÈ£¸£¸ó
  • ADH =£¾antidiuretic hormone
    Ç×ÀÌ´¢È£¸£¸ó
  • CRH (corticotropin releasing hormone)
    ÄÚ¸£Æ¼ÄÚÆ®·ÎÇÉ ºÐºñÈ£¸£¸ó
¿¾ ´ëÇÑÀÇÇù 3 ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • adrenal cortical hormone =adrenocortical hormone
    ºÎ½ÅÇÇÁúÈ£¸£¸ó
  • corpus luteum hormone (=luteal hormone)<³ª>
    Ȳü(üÜô÷)È£¸£¸ó.
  • luteinizing hormone-releasing hormone
    Ȳüȭȣ¸£¸óÀÚ±ØÈ£¸£¸ó
  • trophic hormone = tropic hormone
    ¿µ¾çÈ£¸£¸ó
  • epidermal melanocyte
    Ç¥ÇǸá¶ó´Ñ¼¼Æ÷
  • melanocyte
    ¸á¶ó´Ñº¸À¯¼¼Æ÷(¡­ÜÁêóá¬øà), ¸á¶ó´Ñ¼¼Æ÷.
  • melanocyte
    ¸á¶ó´Ñ¼¼Æ÷
  • melanocyte
    ¸á¶ó´Ñº¸À¯¼¼Æ÷,¸á¶ó´Ñ¼¼Æ÷
  • melanocyte
    ¸á¶ó´Ñ¼¼Æ÷, Èæ»ö¼¼Æ÷
  • melanocyte
    ¸á¶ó´Ñ¼¼Æ÷, ¸á¶ó´Ñ º¸À¯¼¼Æ÷
  • melanocyte of choroid
    ¸Æ¶ô¸·¸á¶ó´Ñ¼¼Æ÷
  • melanocyte system
    ¸á¶ó´Ñ¼¼Æ÷°è(¡­á¬øàͧ).
  • melanocyte system
    ¸á¶ó´Ñ¼¼Æ÷°è(¡­á¬øàͧ)
  • adrenergic drug =a. stimulating agent
    ¾Æµå·¹³¯¸°¾à.
  • adrenergic drug =a. stimulating agent
    ¾Æµå·¹³¯¸°¼º¾à¹°
´ëÇÑ»ýÈ­ÇкÐÀÚ»ý¹°ÇÐȸ ¿ë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • eIF-2 stimulating protein
    eIF-2 ÀÚ±Ø ´Ü¹éÁú(í©Ð½Ó±ÛÜòõ)
  • insulin stimulating test
    Àν¶¸° ÀڱؽÃÇè(í©Ð½ãËúÐ)
  • adipokinetic hormone
    Áö¹æµ¿¿ø(ò·Û²ÔÑê¬)È£¸£¸ó
  • adrenal cortical hormone
    ºÎ½ÅÇÇÁú(Üùãìù«òõ)È£¸£¸ó
  • adrenocorticotropic hormone
    ºÎ½ÅÇÇÁúÀÚ±Ø(Üùãìù«òõ í©Ð½)È£¸£¸ó
  • animal hormone
    µ¿¹°(ÔÑÚª)È£¸£¸ó
  • antidiuretic hormone
    Ç×ÀÌ´¢(ù÷××Òã)È£¸£¸ó
  • autocrine hormone
    ÀÚ°¡ºÐºñ (í»Ê«ÝÂÝô) È£¸£¸ó
  • brain hormone
    ³ú(Òà)È£¸£¸ó
  • chemotactic hormone
    È­ÇÐÁÖ¼º(ûùùÊñËàõ) È£¸£¸ó
  • corticotropin releasing hormone
    ÄÚ¸£Æ¼ÄÚÆ®·ÎÇÉ À¯¸®(ë´×î) È£¸£¸ó
  • diabetogenic hormone
    ´ç´¢º´¹ß»ý(ÓØÒãÜ»Û¡ßæ)È£¸£¸ó
  • eclosion hormone
    ¿ìÈ­(éâûù) È£¸£¸ó
  • ectopic hormone syndrome
    À̼Ò(ì¶á¶) È£¸£¸ó ÁõÈıº(ñøý¦ÏØ)
  • emergency hormone
    ÀÀ±Þ(ëëÐá) È£¸£¸ó
KI ÀÇÇпë¾î »çÀü °Ë»ö À¯»ç °Ë»ö °á°ú : 1 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
  • thyrotropic hormone
    °©»ó¼±ÀÚ±ØÈ£¸£¸ó
KMLE ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 2
MIF macrophage inhibitory factor; melanocyte[-stimulating hormone]-inhibiting factor; maximum inspirator...
MRF Markov random field; medical record file; melanocyte-[stimulating hormone]-releasing factor; mesence...
MRIF melanocyte[-stimulating hormone] release-inhibiting factor
MSHIF melanocyte-stimulating hormone-inhibiting factor
MSHR melanocyte stimulating hormone receptor
KMLE ÀÚµ¿ÃßÃâ ÀÇÇоà¾î »çÀü À¯»ç °Ë»ö °á°ú : 5 ÆäÀÌÁö: 2
gamma-MSH gamma- melanocyte stimulating hormone
MSH gamma-melanocyte stimulating hormone
GM-CSF Granulocyte colony-stimulating factor , granulocyte-macrophage colony-stimulating factor
G-CSF Granulocyte-Macrophage Colony-Stimulating Factor , Granulocyte Colony-Stimulating Factor
TSH E--thyroid-stimulating hormone
°æºÏ´ë Ä¡°ú´ëÇÐ ±¸°­³»°ú ±³½Ç »çÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
  • ¿µ¹®
    ÇѱÛ
    ¼³¸í
  • corticosteroid hormone
    ÄÚÆ¼ÄÚ½ºÅ×·ÎÀ̵å È£¸£¸ó
  • female hormone
    ¿©¼º È£¸£¸ó
    ôÃß µ¿¹° ¾ÏÄÆÀÇ ³­¼Ò¿¡¼­ ºÐºñµÇ¾î ¼º±âÀÇ ¹ßÀ°°ú »ý½Ä±â´É Á¶Àý µî¿¡ ÀÛ¿ëÇÏ´Â ¼º È£¸£¸ó. ³­¼Ò È£¸£¸óÀ̶ó°íµµ ÇÑ´Ù. ¿©Æ÷¿¡¼­ ³ª¿À´Â ¿©Æ÷ È£¸£¸ó°ú Ȳü¿¡¼­ ³ª¿À´Â Ȳü È£¸£¸óÀÌ ÀÖ´Ù. ÀÇ¾à ¹æ¸é¿¡¼­ º¸Åë ¿©¼º È£¸£¸óÀ̶ó°í ÇÒ ¶§´Â ¿©Æ÷ È£¸£¸óÀ» ¸»ÇÑ´Ù. ¿©Æ÷ È£¸£¸óÀº ¹ßÁ¤ È£¸£¸óÀ¸·Î ¿©¼º »ý½Ä±âÀÇ ¹ßÀ°À» ÃËÁøÇÏ¿© ¿©¼º´Ù¿òÀ» ÁõÁø½ÃŲ´Ù. Ȳü È£¸£¸óÀº ¹ßÁ¤ È£¸£¸ó¿¡ ±æÇ×ÀûÀ¸·Î ÀÛ¿ëÇÏ¿© ¹ßÁ¤À» ¾ïÁ¦ÇÑ´Ù. À̵é È£¸£¸óÁ¦ÀÇ »ç¿ëÀº ÀÎü¿¡ ÀÌ»óÇÑ ¹ÝÀÀÀ» ÀÏÀ¸Å°´Â ¼ö°¡ ÀÖÀ¸¹Ç·Î ±× »ç¿ëÀº ¹Ýµå½Ã Àü¹® ÀÇ»çÀÇ Áö½Ã¿¡ µû¶ó¾ß ÇÑ´Ù. ¹ßÁ¤ È£¸£¸óÀÇ ÀÛ¿ëÀ» °¡Áø ¹°ÁúÀ» ÃÑÄªÇØ¼­ ¿¡½ºÆ®·Î°Õ
  • follicular hormone
    ¿©Æ÷ È£¸£¸ó
    ôÃßµ¿¹°ÀÇ ³­¼Ò ¾È¿¡ ÀÖ´Â ³­Æ÷¿¡¼­ ºÐºñµÇ´Â ÀÚ¼º È£¸£¸ó. ³­Æ÷ È£¸£¸ó, ¹ßÁ¤ È£¸£¸óÀ̶ó°íµµ ÇÑ´Ù. »ý½Ä±â¸¦ ¹ßÀ°½ÃŰ°í ±× ±â´ÉÀ» ³ªÅ¸³»µµ·Ï ÇÏ¿© Á¦2Â÷ ¶Ç´Â Á¦3Â÷ ¼ºÂ¡À» ¹ß´Þ½Ã۴µ¥, ƯÈ÷ Æ÷À¯·ù¿¡¼­ ¹ßÁ¤À» ÀÏÀ¸Å°°Ô ÇÏ´Â µ¥¼­ ¹ßÁ¤ È£¸£¸óÀ̶ó´Â À̸§ÀÌ ºÙ¾ú´Ù. ³­¼Ò À̿ܿ¡µµ ŹÝÀ» ºñ·ÔÇÏ¿© ºÎ½Å ÇÇÁúÀ̳ª Á¤¼Ò·ÎºÎÅÍ ¼Ò·® ºÐºñµÇ´Âµ¥ ¿¡½ºÆ®·ÐÀ̳ª ¿¡½ºÆ®¶óµð¿Ã ¹× ÀÎü¿¡¼­ º¼ ¼ö ÀÖ´Â ¿¡½ºÆ®¸®¿Ã µî 3Á¾·ùÀÇ ½ºÅ×·ÎÀ̵尡 ¾Ë·ÁÁ® ÀÖ´Ù. È­ÇÐÀûÀ¸·Î ¾ÈÁ¤µÇ¾î ÀÖÀ¸¸ç Àڱà ¹ßÀ°, ³»¸· Áõ½Ä, Á¥»ù ¹ßÀ°, ±ÔÄ¢Àû ¿ù°æ, Á¦2Â÷ ¼ºÂ¡ µîÀ» ÃËÁøÇÑ´Ù. ÀÌ È£¸£¸óÀÇ ºÐºñ´Â ³úÇϼöü Àü¿±¿¡¼­ ºÐºñµÇ´Â ¿©Æ÷ ÀÚ±Ø È£¸£¸ó
  • hormone antagonist
    Ç×È£¸£¸ó ¾à, Ç×È£¸£¸ó ¹°Áú
  • hormone dependent tumor
    È£¸£¸ó ÀÇÁ¸¼º Á¾¾ç
  • hormone like action
    È£¸£¸ó À¯»ç ÀÛ¿ë
    ü³»¿¡ µé¾î¿Í È£¸£¸ó°ú ºñ½ÁÇÑ ¿ªÇÒÀ» ÇÏ´Â °Í.
  • hormone recenptor
    È£¸£¸ó ¼ö¿ëü
    È£¸£¸óÀÌ ÀÛ¿ëÇÏ´Â ºÎÀ§¿¡¼­ È£¸£¸óÀÌ °áÇÕÇÏ´Â °÷.
  • human growth hormone
    ¼ºÀå È£¸£¸ó
    ¼ºÀåÀ» ÃËÁøÇÏ´Â ¹°ÁúÀ» ÃÑĪÇϸç, ƯÈ÷ ³úÇϼöü Àü¿±¿¡¼­ ºÐºñµÇ´Â È£¸£¸óÀ» ¸»ÇÑ´Ù.
  • hypothalamic hormone
    ½Ã»ó ÇϺΠȣ¸£¸ó
  • hypothalamic hypophysiotropic hormone
    ½Ã»ó ÇϺμº Çâ³úÇϼöü¼º È£¸£¸ó
  • inhibitory hormone
    ¾ïÁ¦ È£¸£¸ó
    Ç¥Àû ±â°ü¿¡ ´ëÇÏ¿© ¾ïÁ¦ÀûÀ¸·Î ÀÛ¿ëÇϴ ȣ¸£¸ó.
  • lactation hormone
    ÃÖÀ¯ È£¸£¸ó
  • luteinizing hormone
    Ȳüȭ È£¸£¸ó, Ȳü Çü¼º È£¸£¸ó
  • luteotropic hormone
    Ȳü ÀÚ±Ø È£¸£¸ó
    Ȳü Çü¼ºÀ» ÀÚ±ØÇÏ´Â Çϼöü Àü¿± È£¸£¸ó.
  • lutinizing hormone
    Ȳüȭ È£¸£¸ó
CancerWEB ¿µ¿µ ÀÇÇлçÀü À¯»ç °Ë»ö °á°ú : 15 ÆäÀÌÁö: 2
growth hormone-regulating hormone <endocrinology> Hypothalamic hormones that induce (somatoliberin) or inhibit (somatostatin) the release of growth hormone (somatotropin).
(18 Nov 1997)
growth hormone-releasing hormone <endocrinology> Peptide hormone related to the glucagon family, released from the pituitary, acts on the adenohypophysis to release growth hormone.
Synonym: somatoliberin, growth hormone-releasing factor.
(20 Sep 2002)
hormones, hormone substitutes, and hormone antagonists A collective grouping for both naturally occurring and synthetic hormones, substitutes, and antagonists.
(12 Dec 1998)
luteinizing hormone-releasing hormone A hormone that controls sex hormones in men and women. Also called lhrh.
(12 Dec 1998)
macrophage colony-stimulating factor <growth factor> A glycoprotein growth factor that causes the committed cell line to proliferate and mature into macrophages.
A cytokine synthesised by mesenchymal cells that stimulates pluripotent stem cells of bone marrow into differentiating towards the production of monocytes (mononuclear phagocytes).
The compound stimulates the survival, proliferation, and differentiation of haematopoietic cells of the monocyte-macrophage series. It is a disulfide-bonded glycoprotein dimer with a mw of 70 kD and binds to a single class of high affinity receptor which is identical to the product of the c-fms proto-oncogene.
See: colony-stimulating factors.
Chemical name: Colony-stimulating factor 1
Acronym: M-CSF
(12 Dec 1998)
receptors, colony-stimulating factor Cell surface receptors for colony-stimulating factors, local mediators, and hormones that regulate the survival, proliferation, and differentiation of haemopoietic cells.
(12 Dec 1998)
receptors, granulocyte-colony-stimulating factor Receptors that bind and internalise granulocyte-colony-stimulating factor. Their mw is believed to be 150 kD. These receptors are found mainly on a subset of myelomonocytic cells.
(12 Dec 1998)
receptors, granulocyte-macrophage colony-stimulating factor Receptors that bind and internalise the granulocyte-macrophage stimulating factor. Their mw is believed to be 84 kD. The most mature myelomonocytic cells, specifically human neutrophils, macrophages, and eosinophils, express the highest number of affinity receptors for this growth factor.
(12 Dec 1998)
receptors, macrophage colony-stimulating factor Glycoproteins of mw 165 kD which are encoded by the c-fms proto-oncogene. The binding of csf-1 to its receptors activates an intrinsic tyrosine kinase activity resulting in autophosphorylation of the receptors on tyrosine, rapid receptor down-regulation, and phosphorylation of as yet unidentified physiologic substrates that initiate a mitogenic response.
(12 Dec 1998)
granulocyte-colony-stimulating factor <growth factor, haematology, oncology> A glycoprotein of 25 kD containing internal disulfide bonds.
It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukaemic myeloid cell lines.
A protein that stimulates the growth and maturation of granulocytes. It is used to promote the recovery of the white cells following chemotherapy.
See: colony-stimulating factor.
Acronym: G-CSF
(12 Dec 1998)
granulocyte-macrophage colony-stimulating factor <growth factor, haematology, oncology> An acidic glycoprotein of mw 23 kD with internal disulfide bonds.
It is produced in response to a number of inflammatory mediators by mesenchymal cells present in the haemopoietic environment and at peripheral sites of inflammation.
It stimulates the production of neutrophilic granulocytes, macrophages, and mixed granulocyte-macrophage colonies from bone marrow cells and can stimulate the formation of eosinophil colonies from foetal liver progenitor cells. It also has some functional activities in mature granulocytes and macrophages.
It is used to promote the recovery of the white blood cells following chemotherapy.
Chemical name: Colony-stimulating factor 2
See: colony-stimulating factor.
Acronym: GM-CSF
(12 Dec 1998)
colony-stimulating factor <cell biology> A glycoprotein growth factor that regulates the differentiation of particular cells.
These substances act in either paracrine or autocrine fashion on marrow cells, appear to act synergistically and can exert actions on several lines of progenitor cells, and influence end cell function. These lymphokines induce the maturation and proliferation of white blood cells from the primitive cell types present in bone marrow such as the leucocyte, macrophage and monocyte lines.
These substances can also be made by recombinant DNA technology for use clinically to speed bone marrow recovery typically following chemotherapy.
Acronym: CSF
(18 Jul 2002)
multi-colony-stimulating factor <cytokine> Product of mitogen activated T-cells: colony-stimulating factor for bone marrow stem cells and mast cells.
A multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. It is considered one of the haematopoietic colony-stimulating factors.
Synonym: multi-CSF
Acronym: IL-3
(12 Dec 1998)
multipotential colony-stimulating factor <cytokine> Product of mitogen activated T-cells: colony-stimulating factor for bone marrow stem cells and mast cells.
A multilineage cell growth factor secreted by lymphocytes, epithelial cells, and astrocytes which stimulates clonal proliferation and differentiation of various types of blood and tissue cells. It is considered one of the haematopoietic colony-stimulating factors.
Synonym: multi-CSF
Acronym: IL-3
(12 Dec 1998)
natural killer cell stimulating factor <cytokine> A 75 kD heterodimeric cytokine composed of disulfide-bonded 40 kD and 35 kD subunits that was originally identified by its ability to induce cytotoxic effector cells in synergy with less than optimal concentrations of interleukin-2.
It is released by macrophages in response to infection and promotes the activation of cell-mediated immunity. Specifically, IL-12 triggers the maturation of Thl CD4 cells, specific cytotoxic T-lymphocyte responses and an increase in the activity of NK cells and consequently, it is the initiator of cell-mediated immunity.
It enhances the lytic activity of NK cells, induces interferon production, stimulates the proliferation of activated T-cells and NK cells. Is secreted by human B lymphoblastoid cells (NC 37). May play a role in controlling immunoglobulin isotype selection as it also inhibits IgE synthesis (even in the presence of anti-IFN monoclonal antibody) and as a growth factor for activated CD4+ and CD8+ T-cells independently of interleukin-2, and for CD56+ NK cells but not resting peripheral blood mononuclear cells or resting or activated tonsillar B-cells.
It is likely that interleukin 12 has a major role in protective immunity against viruses and is under study as an immunotherapy in HIV infection.
Formerly referred to as cytotoxic lymphocyte maturation factor.
Acronym: IL-12
(12 Dec 1998)
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