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nonsuppressible insulin-like activity A blood protein (nsila) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of cohn fraction III, 10% of the activity is found in the supernatant (nsila-s) and the remaining activity in the precipitate (nsila-p). The latter is a large molecular compound, much less stable than the soluble fraction. Nsila-s is a more potent growth factor than insulin and exhibits sulfation activity.
(12 Dec 1998)
drug activity A measure of the physiological response a drug produces. A less active drug produces less response (and visa versa).
(12 Dec 1998)
insulin-like activity A measure of substances, usually in plasma, that exert biologic effects similar to those of insulin in various bioassays; sometimes used as a measure of plasma insulin concentrations; always gives higher values than immunochemical techniques for the measurement of insulin.
(05 Mar 2000)
intrinsic sympathomimetic activity The property of a drug that causes activation of adrenergic receptors so as to produce effects similar to stimulation of the sympathetic nervous system.
(05 Mar 2000)
optical activity The ability of a material to rotate the plane of polarized light.
(09 Oct 1997)
triggered activity One or a series of spontaneously generated heart beats originating from an action potential that produces an after-depolarisation which reaches activation threshold.
(05 Mar 2000)
unit of thyrotrophic activity The activity of an amount of an extract of the anterior lobe of the hypophysis which, given daily for 5 days, will cause the thyroid of a guinea pig (weighing 200 g) to reach a weight of 600 mg.
(05 Mar 2000)
zone of polarizing activity <cell biology> The small group of mesenchyme cells in avian limb buds that is located at the posterior margin of the developing bud and that produces a substance, possibly retinoic acid, that provides positional information to the developing limb bud.
(18 Nov 1997)
arithmetic mean The mean calculated by adding a set of values and then dividing the sum by the number of values.
(05 Mar 2000)
calculated mean organism A hypothetical organism whose characters are the means of both the positive and negative characters of the organism's which belong to the same taxon as the CMO, as opposed to the hypothetical mean. Organism.
(05 Mar 2000)
geometric mean The mean calculated as the antilogarithm of the arithmetic mean of the logarithms of the individual values; it can also be calculated as the nth root of the product of n values.
(05 Mar 2000)
geometric mean diameter A measure of the central tendency of particle size composition of substrate materials sometimes used as an index of the quality of spawning gravels. Also referred to as D50 size.
(09 Oct 1997)
mean <statistics> Average value calculated by taking the sum of all values and dividing by the total number of values.
(05 Jan 1998)
mean annual increment The annual average growth rate for a tree, computed over its entire life cycle.
(05 Dec 1998)
mean arterial pressure <cardiology, physiology> The average value for arterial pressure. Systolic pressure + diastolic pressure divided by 2.
(27 Sep 1997)
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