| physical map | <molecular biology> A map of the locations of identifiable landmarks on DNA (for example, restriction enzyme cutting site, genes), regardless of inheritance. Distance is measured in base pairs. For the human genome, the lowest-resolution physical map is the banding patterns on the 24 different chromosomes, the highest-resolution map wouldbe the complete nucleotide sequence of the chromosomes. (09 Oct 1997) |
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| conformational map | A graphical representation in which the dihedral angle of rotation about the alpha-carbon to carbonyl-carbon bond in polypeptides is plotted against the dihedral angle of rotation about the alpha-carbon to nitrogen bond. Synonym: conformational map. (05 Mar 2000) |
| contiguous map | <molecular biology> A map depicting the relative order of a linked library of small overlapping clones representing a complete chromosomal segment. (10 Nov 1998) |
| cosmid map | <molecular biology> A physical map that includes a collection of bacteria containing cosmids that carry the DNA fragments under study. (10 Nov 1998) |
| cytogenetic map | A map in which the classical bonding pattern of a chromosome is shown. (05 Mar 2000) |
| sequence-tagged site map | A map representing the order and spacing of sequence-tagged sites within a stretch of DNA. (05 Mar 2000) |
| topographic map | <anatomy, neurology> The spatially ordered projection of neurons onto their target, for example in the retino tectal projection, retinal ganglion cell axons project along the optic nerve to the contralateral tectum where they ramify to form terminal arbors. The target sites of the terminal arbors are ordered: neurons from a specific region of the retina consistently project to a specific region of the tectum, forming a map of the retina on the tectum. (18 Nov 1997) |
| y map | The array of genes on the y chromosome. Once thought to be a genetic wasteland, the y now is known to contain at least 20 genes, some of them unique to the y including the male-determining gene and male fitness genes that are active only in the testis and are thought responsible for the formation of sperm. Other genes on the y have counterparts on the x chromosome, are active in many body tissues and play crucial housekeeping roles with the cell. (12 Dec 1998) |
| fate map | <embryology> Diagram of an early embryo (usually a blastula) showing which tissues the cells in each region will give rise to (i.e. Their developmental fate). Fate maps are normally constructed by labelling small groups of cells in the blastula with vital dyes and seeing which tissues are stained when the embryo develops. (18 Nov 1997) |
| linkage map | <genetics> A map of the relative positions of genetic loci on a chromosome, determined onthe basis of how often the loci are inherited together. Distance ismeasured in centimorgans (cM). (09 Oct 1997) |