| hydatiform mole | <radiology> Trophoblastic proliferation with avascularity of chorionic villi, marked oedema and enlargement of chorionic villi, severe eclampsia prior to 24 weeks, 1st trimester bleeding, abnormal elevation of beta-hCG, passing grapelike vesicles per vagina, uterus large for dates (50%), hyperechoic intrauterine tissue interspersed with numerous punctate hypoechoic areas (hydropic villi), in 25% atypical appearance: large hyperechoic areas (blood clots) and areas of cystic degeneration; resembles incomplete abortion, thick hyperechoic rim around central anechoic zone, bilateral theca lutein cysts (18-37%) see also: gestational trophoblastic disease, hydatiform mole: types (12 Dec 1998) |
|---|---|
| hydatiform mole: types | <radiology> Complete/classical mole, fertilization of an empty egg; diploid karyotype (paternal XX), no foetal parts; no chorionic membrane, 20% malignant complete mole with coexistent foetus (2%), molar degeneration of an identical twin partial mole, areas of molar change alternating with normal chorionic villi, triploid karyotype (66% XXY; 33% XXX), early onset of preeclampsia, foetal structures present (e.g., placenta), no malignant potential see: hydatiform mole (12 Dec 1998) |
| spider mole | spider angioma |
| invasive mole | chorioadenoma destruens |
| false mole | <gynaecology> An intrauterine polyp. (05 Mar 2000) |
| fleshy mole | A uterine mass occurring after foetal death and consisting of blood clots, foetal membranes, and placenta. Synonym: blood mole, carneous mole. (05 Mar 2000) |
| cancer, malignant melanoma | A skin cancer that begins in cells called melanocytes that can grow together to form benign (not cancerous) moles. A change in size, shape, or colour of a mole can be a sign of melanoma. Melanoma can be cured if detected early, before spread (metastasis) to other areas of the body. Diagnosis is confirmed with a biopsy of the abnormal skin. Sun exposure can cause skin damage that can lead to melanoma. (12 Dec 1998) |
| canine malignant lymphoma | <tumour> A progressive fatal disease of dogs characterised by neoplastic transformation and proliferation of lymphoid cells, usually originating in solid lymphoid organs (lymphosarcoma) or bone marrow (lymphocytic leukaemia). (05 Mar 2000) |
| malignant | <oncology> Tending to become progressively worse and to result in death. Having the properties of anaplasia, invasion and metastasis, said of tumours. Origin: L. Malignans = acting maliciously (18 Nov 1997) |
| malignant anaemia | <haematology> A form of anaemia (low red blood cell counts) that results when the bone marrow fails to produce adequate numbers of red blood cells due to a deficiency in vitamin B12. Intrinsic factor, necessary for normal B12 absorption, may be the underlying cause for B12 deficiency if is not produced in the gastric glands (in the stomach). Origin: Gr. Haima = blood (27 Sep 1997) |
| malignant catarrh | A herpes virus infection of cattle characterised by catarrhal inflammation of the upper respiratory and alimentary epithelia, keratoconjunctivitis, encephalitis and lymph node enlargement. Syn: bovine epitheliosis, snotsiekte. (12 Dec 1998) |
| malignant catarrhal fever | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
| malignant catarrhal fever virus | A herpesvirus of wide distribution causing malignant catarrhal fever of cattle; sheep and wildebeests harbor inapparent infections and may transmit the virus to cattle. (05 Mar 2000) |
| malignant catarrh of cattle | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
| malignant ciliary epithelioma | <tumour> Malignant hyperplasia of ciliary epithelium with frequent involvement of the pigmented layer. Synonym: adult medulloepithelioma. (05 Mar 2000) |