| malignant carcinoid syndrome | <syndrome> A symptom complex associated with carcinoid tumour and characterised by attacks of severe flushing of the skin, diarrhoeal watery stools, bronchoconstriction, sudden drops in blood pressure, oedema, and ascites. The carcinoid tumours are usually located in the gastrointestinal tract and metastasize to the liver. Symptoms are caused by tumour secretion of serotonin, prostaglandins, and other biologically active substances. Cardiac manifestations constitute carcinoid heart disease. (12 Dec 1998) |
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| malignant catarrh | A herpes virus infection of cattle characterised by catarrhal inflammation of the upper respiratory and alimentary epithelia, keratoconjunctivitis, encephalitis and lymph node enlargement. Syn: bovine epitheliosis, snotsiekte. (12 Dec 1998) |
| malignant catarrhal fever | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
| malignant catarrhal fever virus | A herpesvirus of wide distribution causing malignant catarrhal fever of cattle; sheep and wildebeests harbor inapparent infections and may transmit the virus to cattle. (05 Mar 2000) |
| malignant catarrh of cattle | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
| malignant dysentery | Dysentery in which the symptoms are intensely acute, leading to prostration, collapse, and often death. Synonym: fulminating dysentery. (05 Mar 2000) |
| malignant dyskeratosis | Dyskeratosis that may occur in precancerous or malignant lesions. (05 Mar 2000) |
| malignant endocarditis | Acute bacterial endocarditis, usually secondary to suppuration elsewhere and running a fulminating course. Synonym: septic endocarditis. (05 Mar 2000) |
| malignant exophthalmos | Relentless, progressive protrusion of the eyeballs. (05 Mar 2000) |
| malignant fibrous histiocytoma | <tumour> A deeply situated tumour, especially on the extremities of adults, frequently recurring after surgery and metastasizing to the lungs; shows partial fibroblastic and histiocytic differentiation with a variable storiform pattern, myxoid areas, and giant cells. (05 Mar 2000) |
| malignant giant cell tumour | A type of bone tumour. (12 Dec 1998) |
| malignant glaucoma | Secondary glaucoma caused by forward displacement of the iris and lens, obliterating the anterior chamber; usually follows a filtering operation for primary glaucoma. (05 Mar 2000) |
| malignant granuloma | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
| malignant hepatoma | <tumour> A carcinoma derived from parenchymal cells of the liver. Synonym: hepatocarcinoma, hepatocellular carcinoma, liver cell carcinoma. (05 Mar 2000) |
| malignant histiocytosis | A rapidly fatal form of lymphoma, characterised by fever, jaundice, pancytopenia, and enlargement of the liver, spleen, and lymph nodes; the affected organs show focal necrosis and haemorrhage, with proliferation of histiocytes and phagocytosis of red blood cells. (05 Mar 2000) |