| malignant catarrh of cattle | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
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| malignant catarrhal fever | A highly fatal, sporadic disease of cattle caused by alcelaphine herpesvirus 1 (a member of the Herpesviridae family) and characterised by inflammation, ulceration, and exudation of the oral and upper respiratory mucous membranes, and sometimes eye lesions and nervous system disturbances. Synonym: malignant catarrh of cattle. (05 Mar 2000) |
| malignant catarrhal fever virus | A herpesvirus of wide distribution causing malignant catarrhal fever of cattle; sheep and wildebeests harbor inapparent infections and may transmit the virus to cattle. (05 Mar 2000) |
| malignant ciliary epithelioma | <tumour> Malignant hyperplasia of ciliary epithelium with frequent involvement of the pigmented layer. Synonym: adult medulloepithelioma. (05 Mar 2000) |
| malignant dysentery | Dysentery in which the symptoms are intensely acute, leading to prostration, collapse, and often death. Synonym: fulminating dysentery. (05 Mar 2000) |
| malignant dyskeratosis | Dyskeratosis that may occur in precancerous or malignant lesions. (05 Mar 2000) |
| malignant endocarditis | Acute bacterial endocarditis, usually secondary to suppuration elsewhere and running a fulminating course. Synonym: septic endocarditis. (05 Mar 2000) |
| malignant exophthalmos | Relentless, progressive protrusion of the eyeballs. (05 Mar 2000) |
| malignant fibrous histiocytoma | <tumour> A deeply situated tumour, especially on the extremities of adults, frequently recurring after surgery and metastasizing to the lungs; shows partial fibroblastic and histiocytic differentiation with a variable storiform pattern, myxoid areas, and giant cells. (05 Mar 2000) |
| malignant giant cell tumour | A type of bone tumour. (12 Dec 1998) |
| malignant glaucoma | Secondary glaucoma caused by forward displacement of the iris and lens, obliterating the anterior chamber; usually follows a filtering operation for primary glaucoma. (05 Mar 2000) |
| malignant granuloma | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
| malignant hepatoma | <tumour> A carcinoma derived from parenchymal cells of the liver. Synonym: hepatocarcinoma, hepatocellular carcinoma, liver cell carcinoma. (05 Mar 2000) |
| malignant histiocytosis | A rapidly fatal form of lymphoma, characterised by fever, jaundice, pancytopenia, and enlargement of the liver, spleen, and lymph nodes; the affected organs show focal necrosis and haemorrhage, with proliferation of histiocytes and phagocytosis of red blood cells. (05 Mar 2000) |
| malignant hyperphenylalaninaemia | DHPR-deficient form; an inherited disorder in which there is an absence or deficiency of dihydropteridine reductase (DHPR); this results in impaired regeneration of tetrahydrobiopterin, causing an elevation in phenylalanine levels, GTP-CH form; an inherited disorder in which there is a deficiency of guanosine triphosphate cyclohydrolase, an enzyme used in the biosynthesis of tetrahydrobiopterin, 6-PTS form; an inherited disorder in which there is a deficiency of 6-pyruvoyl tetrahydropterin synthase, an enzyme that participates in the biosynthesis of tetrahydrobiopterin. Synonym: nonclassical phenylketonuria. (05 Mar 2000) |