| LCRB | locus control region beta |
|---|---|
| LOC | laxative of choice; level of consciousness; liquid organic compound; locus of control; loss of consc... |
| MHLC | Multidimensional Health Locus of Control |
| TCA | T-cell A locus; terminal cancer; tetracyclic antidepressant; total cholic acid; total circulating al... |
| TPL | third party liability; titanium proximal loading; tumor progression locus; tyrosine phenol-lyase |
| sex-linked locus | Any locus that in normal karyotypes is borne on a heterosome; commonly but incorrectly applied to an X-linked locus. (05 Mar 2000) |
|---|---|
| Y-linked locus | Any (haploid) locus that in normal karyotypes is borne on the Y chromosome. The known content is so far small. (05 Mar 2000) |
| locus | <genetics> The site in a linkage map or on a chromosome where the gene for a particular trait is located. Any one of the alleles of a gene may be present at this site. (18 Nov 1997) |
| locus ceruleus | A shallow depression, of a blue colour in the fresh brain, lying laterally in the most rostral portion of the rhomboidal fossa near the cerebral aqueduct; it lies near the lateral wall of the fourth ventricle and consists of about 20,000 melanin-pigmented neuronal cell bodies whose norepinephrine-containing axons have a remarkably wide distribution in the cerebellum as well as in the hypothalamus and cerebral cortex. Synonym: substantia ferruginea, locus cinereus, locus ferrugineus. (05 Mar 2000) |
| locus cinereus | A shallow depression, of a blue colour in the fresh brain, lying laterally in the most rostral portion of the rhomboidal fossa near the cerebral aqueduct; it lies near the lateral wall of the fourth ventricle and consists of about 20,000 melanin-pigmented neuronal cell bodies whose norepinephrine-containing axons have a remarkably wide distribution in the cerebellum as well as in the hypothalamus and cerebral cortex. Synonym: substantia ferruginea, locus cinereus, locus ferrugineus. (05 Mar 2000) |
| locus coeruleus | Bluish region in the superior angle of the fourth ventricle floor, corresponding to melanin-like pigmented nerve cells which lie lateral to the ponto-mesencephalic central gray (griseum centrale). It is also known as nucleus pigmentosus pontis, locus cinereus, and locus ferrugineus. (12 Dec 1998) |
| locus control region | A regulatory region first identified in the human beta-globin locus but subsequently found in other loci. The region is believed to regulate transcription by opening and remodeling chromatin structure. It may also have enhancer activity. (12 Dec 1998) |
| locus ferrugineus | A shallow depression, of a blue colour in the fresh brain, lying laterally in the most rostral portion of the rhomboidal fossa near the cerebral aqueduct; it lies near the lateral wall of the fourth ventricle and consists of about 20,000 melanin-pigmented neuronal cell bodies whose norepinephrine-containing axons have a remarkably wide distribution in the cerebellum as well as in the hypothalamus and cerebral cortex. Synonym: substantia ferruginea, locus cinereus, locus ferrugineus. (05 Mar 2000) |
| locus minoris resistentiae | A place of less resistance, in latin. For example, a damaged heart valve may act as a locus minoris resistentiae where bacteria released into the blood stream (bacteraemia) tend to settle. (12 Dec 1998) |
| locus niger | A large cell mass, crescentic on transverse section, extending forward over the dorsal surface of the crus cerebri from the rostral border of the pons into the subthalamic region; it is composed of a dorsal stratum of closely spaced pigmented (i.e., melanin-containing) cells, the pars compacta, and a larger ventral region of widely scattered cells, the pars reticulata; the pars compacta in particular includes numerous cells that project forward to the striatum (caudate nucleus and putamen) and contain dopamine, which acts as the transmitter substance at their synaptic endings; other, apparently non-dopaminergic cells of the substantia nigra project to a rostral part of the ventral nucleus of thalmus, the middle layers of the superior colliculus and to restricted parts of the reticular formation of the midbrain; the nigrostriatal projection is reciprocated by a massive striatonigral fibre system with multiple neurotransmitters, chief among which is gamma-aminobutyric acid (GABA); substantia n. Receives smaller afferent projections from the subthalamic nucleus, the lateral segment of the globus pallidus, the dorsal nucleus of the raphe and the pedunculopontine nucleus of the midbrain. The pars reticulata forms part of the output system for the striate body. The substantia n. Is involved in the metabolic disturbances associated with Parkinson's disease and Huntington's disease. Synonym: locus niger, nucleus niger, Soemmerring's ganglion. (05 Mar 2000) |
| locus of control | A theoretical construct designed to assess a person's perceived control over his/her own behaviour; classified as internal if the person feels in control of events, external if others are perceived to have that control. (05 Mar 2000) |