| CSC | blow on blow (administration of small amounts of drugs at short intervals) [Fr. coup sur coup]; coll... |
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| DASD | direct access storage device |
| DSO | digital storage oscilloscope; distal subungual onychomycosis |
| EDSR | electronic document storage and retrieval |
| GSD | genetically significant dose; Gerstmann-Straussler disease; glutathione synthetase deficiency; glyco... |
| lipid bilayers | Layers of lipid molecules which are two molecules thick. Bilayer systems are frequently studied as models of biological membranes. (12 Dec 1998) |
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| lipid granulomatosis | <dermatology, pathology> An accumulation of an excess of lipids in the body due to disturbance of lipid metabolism and marked by the formation of foam cells in skin lesions. (16 Dec 1997) |
| lipid histiocytosis | Histiocytosis with cytoplasmic accumulation of lipid, either phospholipid (Niemann-Pick disease) or glucocerebroside (Gaucher's disease). (05 Mar 2000) |
| lipid keratopathy | Occurrence of fats in an area of corneal vascularization. (05 Mar 2000) |
| lipid mobilization | The breakdown of stored triglyceride in adipose tissue with the release of free fatty acids and glycerol. Depot fat hydrolysis is catalyzed by a lipase in response to pituitary lipid mobilization factors (lmf), various hormones, serotonin, or hepatotoxins such as carbon tetrachloride. (12 Dec 1998) |
| lipid-mobilizing hormone | <protein> Polypeptide hormone (_ form: 9894D, 91 residues, _ form has only residues 1-58 of _) from the pituitary hypophysis, that is of particular interest because it is the precursor of endorphins, which are released by proteolysis. Promotes lipolysis and acts through the adenylyl cyclase system. Part of the ACTH group of hormones. (18 Nov 1997) |
| lipid peroxidation | Peroxidase catalyzed oxidation of lipids using hydrogen peroxide as an electron acceptor. (12 Dec 1998) |
| lipid peroxides | Peroxides produced in the presence of a free radical by the oxidation of unsaturated fatty acids in the cell in the presence of molecular oxygen. The formation of lipid peroxides results in the destruction of the original lipid leading to the loss of integrity of the membranes. They therefore cause a variety of toxic effects in vivo and their formation is considered a pathological process in biological systems. Their formation can be inhibited by antioxidants, such as vitamin e, structural separation or low oxygen tension. (12 Dec 1998) |
| lipid pneumonia | Lipoid pneumonia, pulmonary condition marked by inflammatory and fibrotic changes in the lungs due to the inhalation of various oily or fatty substances, particularly liquid petrolatum, or resulting from accumulation in the lungs of endogenous lipid material, either cholesterol from obstructive pneumonitis or following fracture of a bone; phagocytes containing lipid are usually present. Synonym: oil pneumonia. (05 Mar 2000) |
| lipid profile | Pattern of lipids in the blood. (A lipid profile usually includes the total cholesterol, high density lipoprotein (hdl) cholesterol, triglycerides, and the calculated low density lipoprotein (ldl) cholesterol. (12 Dec 1998) |
| brancher glycogen storage disease | Type of glycogen storage disease, due to deficiency of amylo-1,4-1,6-transglucosidase (brancher enzyme). Synonym: brancher deficiency glycogenosis, debrancher deficiency. (05 Mar 2000) |
| glycogen storage disease | <hepatology> A group of inherited metabolic disorders involving the enzymes responsible for the synthesis and degradation of glycogen. In some patients, prominent liver involvement is presented. In others, more generalised storage of glycogen occurs, sometimes with prominent cardiac involvement. Synonym: glycogenosis (12 Sep 2002) |
| glycogen storage disease type I | <disease> An autosomal recessive disease in which gene expression of glucose-6-phosphatase is absent, resulting in hypoglycaemia due to lack of glucose production. Accumulation of glycogen in liver and kidney leads to organomegaly, particularly massive hepatomegaly. Increased concentrations of lactic acid and hyperlipidemia appear in the plasma. Clinical gout often appears in early childhood. Inheritance: autosomal recessive. (12 Dec 1998) |
| glycogen storage disease type II | <disease> Glycogenosis due to alpha-1,4-glucosidase (acid maltase) deficiency. It affects muscle, heart, and other organs. (12 Dec 1998) |
| glycogen storage disease type III | <disease> An autosomal recessive metabolic disorder due to deficient expression of amylo-1,6-glucosidase (one part of the glycogen debranching enzyme system). The clinical course of the disease is similar to that of glycogen storage disease type I, but milder. Massive hepatomegaly, which is present in young children, diminishes and occasionally disappears with age. Levels of glycogen with short outer branches are elevated in muscle, liver, and erythrocytes. Six subgroups have been identified, with subgroups type IIIa and type IIIb being the most prevalent. Inheritance: autosomal recessive (12 Dec 1998) |