| LLETZ | large loop excision of the transformation zone |
|---|---|
| LTT | lactose tolerance test; leucine tolerance test; limited treadmill test; lymphocyte transformation te... |
| NTZ | normal transformation zone |
| PBLT | peripheral blood lymphocyte transformation |
| PNT | partial nodular transformation; patient |
| transformation constant | <physics, radiobiology> The fraction of the amount of a radionuclide that undergoes transition per unit time. Formally: Lamda=dP/dt Where dP is the probability of a given nucleus undergoing spontaneous nuclear transition in the time interval dt. (16 Dec 1997) |
|---|---|
| transformation efficiency | The number of bacterial cells that uptake and express plasmid DNA divided by the mass of plasmid used (in transformants/microgram). (09 Oct 1997) |
| transformation, genetic | The unidirectional transfer and incorporation of foreign DNA by prokaryotic or eukaryotic cells and the subsequent recombination of part or all of that DNA into the cell's genome. (glossary of genetics: classical and molecular, 5th ed) (12 Dec 1998) |
| transformation zone | Zone on the cervix at which squamous epithelium and columnar epithelium meet; changes location in response to a woman's hormonal status. (05 Mar 2000) |
| Lobry de Bruyn-van Ekenstein transformation | The conversion of glucose to fructose and mannose in dilute alkali by enolization adjacent to the carbonyl group to form an enediol, a reaction analogous to certain biochemical transformations. (05 Mar 2000) |
| logit transformation | A method of linearizing dose-response curves for radioimmunoassay techniques; i.e., Logit B (bound)/Bo(initial binding) = Log (B/Bo/1-B/Bo). (05 Mar 2000) |
| lymphocyte transformation | <haematology> The change in morphology and behaviour of lymphocytes exposed to a mitogen or to an antigen to which they have been primed. The result is the production of lymphoblasts, cells that are actively engaged in protein synthesis and that divide to form effector populations. Should not be confused with transformation of the type associated with oncogenic viruses and activation is therefore perhaps a better term. (18 Nov 1997) |
| adhesion structures linked tyrosine kinase | <enzyme> Isolated from mouse embryonic stem cells Registry number: EC 2.7.1.- Synonym: hyk protein (26 Jun 1999) |
| benzylviologen-linked aldehyde oxidoreductase | <enzyme> A coenzyme a-independent tungsten-containing aldehyde oxidoreductase; from desulfovibrio gigas; n-terminal amino acid sequence given in first source Registry number: EC 1.2.7.- Synonym: bv-aldh (26 Jun 1999) |
| recessive, x-linked | A gene on the X chromosome that expresses itself only when there is no different gene present at that locus (spot on the chromosome). For example, duchenne muscular dystrophy (dmd) is an x-linked recessive disorder. A dmd boy has the dmd gene on his sole x chromosome (and so is said to be hemizgous for dmd). Although it is much rarer, a girl can have dmd (by several different means as, for example, if she has the dmd gene on both her x chromosomes and so is homozygous for dmd). (12 Dec 1998) |
| x-linked | On the X chromosome. Linked in genetics does not mean merely associated. An x-linked gene travels with the x chromosome and therefore is part of the x chromosome. (12 Dec 1998) |
| X linked disease | <disease, genetics> A genetic or inherited disease whose controlling gene or at least part of the relevant genome is carried on an X chromosome, for example haemophilia. most known conditions are recessive and thus since males have only one X chromosome they will express any such recessive character. Few dominants are known and the homozygous states are very rare so that female expression of such diseases is uncommon. (18 Nov 1997) |
| X-linked gene | A gene located on an X chromosome. (05 Mar 2000) |
| X-linked hypogammaglobulinaemia | A congenital, X-linked recessive, primary immunodeficiency characterised by decreased numbers (or absence) of circulating B-lymphocytes with corresponding decrease in immunoglobulins of the five classes; associated with marked susceptibility to infection by pyogenic bacteria (notably, pneumococci and Haemophilus influenzae) beginning after loss of maternal antibodies. X-linked hypogammaglobulinaemia with growth hormone deficiency, hypogammaglobulinaemia combined with a reduced number of B-cells; characterised by short stature, delayed puberty, and recurrent infections. (05 Mar 2000) |
| X-linked ichthyosis | A form of ichthyosis, due to 3-beta-hydroxysteroidsulfate sulfatase deficiency, that appears at birth or in early infancy and affects males; characterised by scaling predominantly on the neck and trunk but not on the palms and soles; histologically, there is hyperkeratosis, a granular layer in the epidermis, and normal epidermal cell turnover. Synonym: steroid sulfatase deficiency. (05 Mar 2000) |