| linkage marker | A locus at which there is a high probability of heterozygotes (indispensible state for linkage analysis), but in itself perhaps of no clinical interest. See: marker locus. (05 Mar 2000) |
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| linkage disequilibrium |
The tendency of alleles located close to each other on the same chromosome to be inherited together.
출처: www.niaaa.nih.gov/publications/arh26-3/165-171.htm
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| linkage disequilibrium |
Greater co-occurrence of two genetic markers (on the same chromosome, as a haplotype) in a population than would be expected for independent markers. Usually, LD is generated when the markers are located close together on the same chromosome. When variants of two genetic loci are in strong LD, the variant seen at one locus are predictive of the variant found at the other on an individual chromosome.
출처: www.genaissance.com/pharmacogenomics/glossary.asp
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| linkage disequilibrium |
a departure from -->Hardy-Weinberg equilibrium due to the fact that sorted alleles are linked, therefore, they don't sort independently.
출처: www.qub.ac.uk/bb/prodohl/TroutConcert/fr_glossary....
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