| LLETZ | large loop excision of the transformation zone |
|---|---|
| LTT | lactose tolerance test; leucine tolerance test; limited treadmill test; lymphocyte transformation te... |
| NTZ | normal transformation zone |
| PBLT | peripheral blood lymphocyte transformation |
| PNT | partial nodular transformation; patient |
| linear skull fracture | A skull fracture resembling a line. (05 Mar 2000) |
|---|---|
| abiotic transformation | <biochemistry> An abiotic transformation is any process in which a chemical in the environment is altered by non-biological mechanisms (such as by exposure to sunlight). (09 Oct 1997) |
| bacterial transformation | <microbiology> A genetics lab procedure where bacteria are induced to accept and incorporate into their genome foreign pieces of cell-less, isolated DNA, often in the form of a plasmid. The DNA to be introduced usually contains a selectable marker so that the bacteria which successfully incorporate the DNA can be selected for. (09 Oct 1997) |
| blast transformation | <haematology> The morphological and biochemical changes in lymphocytes, both B and T, on exposure to antigen or to a mitogen. The cells appear to move from G0 to G1 stage of the cell cycle. They usually enlarge and proceed to S phase and mitosis later. The process probably involves receptor cross linking on the plasma membrane. (18 Nov 1997) |
| genetic transformation | <molecular biology> Genetic change brought about by the introduction of exogenous DNA into a cell. See: transformation, germ line transformation, transfection. (18 Nov 1997) |
| germ line transformation | Micro injection of foreign DNA into an early embryo, so that it becomes incorporated into the germ line of the individual and thus stably inherited in subsequent generations of transgenic organisms. Typically, the DNA would be a reporter gene or cDNA in a vector such as a transposon, that might also carry a visible marker gene such as eye or coat colour), so that successful transformation could readily be detected. (18 Nov 1997) |
| viral transformation | <oncology, virology> Malignant transformation of an animal cell in culture, induced by a virus. (18 Nov 1997) |
| cell transformation | Morphological and physiological changes resulting from infection of an animal cell by an oncogenic virus. (05 Mar 2000) |
| cell transformation, neoplastic | Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. (12 Dec 1998) |
| cell transformation, viral | An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. (12 Dec 1998) |
| Haldane transformation | The multiplication of inspired oxygen concentration by the ratio of expired to inspired nitrogen concentrations in the calculation of oxygen consumption or respiratory quotient by the open circuit method. (05 Mar 2000) |
| sol gel transformation | Transition between more fluid cytoplasm (endoplasm) and stiffer gel like ectoplasm proposed as a mechanism for amoeboid locomotion: since the endoplasm cannot really be considered a simple fluid and has visco elastic properties like a gel, the term is misleading. (18 Nov 1997) |
| spontaneous transformation | Transformation of a cultured cell that occurs without the deliberate addition of a transforming agent. Cells from some species, especially rodents, are particularly prone to such spontaneous transformation. (18 Nov 1997) |
| nodular transformation of the liver | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| transformation | <chemistry> The change of form or structure, conversion from one form to another. <oncology> The change that a normal cell undergoes as it becomes malignant. In eukaryotes, the conversion of normal cells to malignant cells in cell culture. Origin: L. Formatio = formation (18 Nov 1997) |