| lethal dose 50 | <pharmacology> The amount, or dosage, of a toxin necessary to kill 50% of the experimental subjects. (16 Mar 1998) |
|---|---|
| lethal dwarfism | Dwarfism leading to intrauterine or neonatal death. (05 Mar 2000) |
| lethal equivalent | A combination of selective effects that on average have the same impact on the composition of the gene pool as one death; e.g., two carriers at 50% risk of dying would be the lethal equivalent of one carrier at 100% risk, in the population genetics of recessive traits lethal equivalent is expressed as twice the sum of the expected number of deaths ascribable to the genetic load. Expression used of the genetic load of recessive genes in heterozygous state that if in homozygous state would cause death or carry a risk of death. The expected number of deaths from all such genes is expressed in lethal equivalent. (05 Mar 2000) |
| lethal factor | A disorder that prevents effective reproduction by those affected; e.g., Klinefelter syndrome. (05 Mar 2000) |
| lethal gene | A gene that produces a genotype that leads to death of the organism before reproduction is possible or that precludes reproduction; for a recessive gene the homozygous or hemizygous state is lethal. (05 Mar 2000) |
| lethal midline granuloma | Destruction of the nasal septum, hard palate, lateral nasal walls, paranasal sinuses, skin of the face, orbit and nasopharynx by an inflammatory infiltrate with atypical lymphocytic and histiocytic cells; presumably a form of lymphoma in most cases. An obsolete term for polymorphic reticulosis. Synonym: granuloma gangrenescens, malignant granuloma, midline malignant reticulosis granuloma. (05 Mar 2000) |
| lethal mutation | <genetics, molecular biology> Mutation that eventually results in the death of an organism carrying the mutation. (18 Nov 1997) |
| alveolar gas | The gas in the pulmonary alveoli, where O2-CO2 exchange with pulmonary capillary blood occurs. Synonym: alveolar air. (05 Mar 2000) |
| alveolar gas equation | The equation defining the steady state relation of the alveolar oxygen pressure to the barometric pressure, inspired gas composition, alveolar carbon dioxide pressure, and respiratory exchange ratio; the equation is used in various forms depending upon which simplifying assumptions are acceptable for different applications. (05 Mar 2000) |
| anaesthetic gas | A gas or a liquid with sufficient vapor pressure to produce general anaesthesia when breathed. (05 Mar 2000) |
| arterial blood gas | A test which analyses arterial blood for oxygen, carbon dioxide and bicarbonate content in addition to blood pH. Used to test the effectiveness of respiration. Acronym: ABG (17 Oct 1997) |
| bivalent gas gangrene antitoxin | Antitoxin specific for the toxins of Clostridium perfringens and C. Septicum. (05 Mar 2000) |
| blood gas analysis | <investigation> A test which analyses arterial blood for oxygen, carbon dioxide and bicarbonate content in addition to blood pH. Used to test the effectiveness of respiration. (27 Sep 1997) |
| blood gas monitoring, transcutaneous | The noninvasive measurement or determination of the partial pressure (tension) of oxygen and/or carbon dioxide locally in the capillaries of a tissue by the application to the skin of a special set of electrodes. These electrodes contain photoelectric sensors capable of picking up the specific wavelengths of radiation emitted by oxygenated versus reduced haemoglobin. (12 Dec 1998) |
| carbonic acid gas | <biochemistry, physiology> A metabolic byproduct of carbohydrate metabolism. Carbon Dioxide collects in the tissues, is cleared by the blood (via the veins) and removed from the body via the lungs when we exhale air. Abbreviation: CO2 (13 Nov 1997) |