| lymphoma, large-cell, ki-1 | A large-cell, non-hodgkin's, malignant lymphoma with pleomorphic appearance and reactivity with the monoclonal antibody ki-1. The lymphoma is most often found in the skin and lymph nodes and expresses the ki-1 (CD30) antigen (antigens, CD30) on its surface. It is often mistaken for metastatic carcinoma and malignant histiocytosis. (12 Dec 1998) |
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| bilateral large kidneys | <radiology> Autosomal dominant (adult) polycystic disease, lymphoma Cf: other urographic patterns (12 Dec 1998) |
| papillary adenoma of large intestine | <tumour> Appears as a solitary sessile, often large, tumour of colonic mucosa composed of mucinous epithelium covering delicate vascular projections; malignant change occurs frequently; hypersecretion occurs rarely. Also known as adenoma. Synonym: papillary adenoma of large intestine. (05 Mar 2000) |
| ribulose-1,5-bisphosphate carboxylase-oxygenase large subunit epsilonN-methyltransferase | <enzyme> An aspect of EC 2.1.1.43; trimethylates lys-14 of rubisco Registry number: EC 2.1.1.- Synonym: rubisco lsmt, rubisco large subunit lysine n-methyltransferase (26 Jun 1999) |
| the large mass of the telencephalon | On either side of the midline, consisting of the cerebral cortex and its associated fibre systems, together with the deeper-lying subcortical telencephalic nuclei (i.e., basal ganglia [nuclei]). (05 Mar 2000) |
| unilateral large kidney | <radiology> Multifocal: xanthogranulomatous pyelonephritis (XGP), malakoplakia, multicystic dysplastic kidney Cf: other urographic patterns smooth kidney: renal vein thrombosis, acute arterial infarction, obstructive uropathy, acute bacterial nephritis, compensatory hypertrophy, duplicated pelvocalyceal system Cf: other urographic patterns multifocal: solid neoplastic mass, malignant, adenocarcinoma, adult nephroblastoma, invasive transitional cell carcinoma, sarcoma, metastasis, benign, hamartoma, adenoma, mesenchymal tumour cystic mass, simple cyst, focal hydronephrosis, multilocular cystic nephroma, arteriovenous malformation Cf: other urographic patterns (12 Dec 1998) |
| large | 1. Exceeding most other things of like in bulk, capacity, quantity, superficial dimensions, or number of constituent units; big; great; capacious; extensive; opposed to small; as, a nlarge horse; a large house or room; a large lake or pool; a large jug or spoon; a large vineyard; a large army; a large city. For linear dimensions, and mere extent, great, and not large, is used as a qualifying word; as, great length, breadth, depth; a great distance; a great height. 2. Abundant; ample; as, a large supply of provisions. "We hare yet large day." (Milton) 3. Full in statement; diffuse; full; profuse. "I might be very large upon the importance and advantages of education." (Felton) 4. Having more than usual power or capacity; having broad sympathies and generous impulses; comprehensive; said of the mind and heart. 5. Free; unembarrassed. "Of burdens all he set the Paynims large." (Fairfax) 6. Unrestrained by decorum; said of language. "Some large jests he will make." 7. Prodigal in expending; lavish. 8. Crossing the line of a ship's course in a favorable direction; said of the wind when it is abeam, or between the beam and the quarter. at large. Without restraint or confinement; as, to go at large; to be left at large. Diffusely; fully; in the full extent; as, to discourse on a subject at large. Common at large. See Common, Electors at large, Representative at large, electors, or a representative, as in Congress, chosen to represent the whole of a State, in distinction from those chosen to represent particular districts in a State. To give, go, run, or sail large, to have the wind crossing the direction of a vessel's course in such a way that the sails feel its full force, and the vessel gains its highest speed. See Large. Synonym: Big, bulky, huge, capacious, comprehensive, ample, abundant, plentiful, populous, copious, diffusive, liberal. Origin: F, fr. L. Largus. Cf. Largo. Source: Websters Dictionary (01 Mar 1998) |
| large breast lesions | <radiology> Breast masses greater than 5 cm, lucent: lipoma, mixed lucent/opaque: fibro-adeno-lipoma, low-density opaque: giant fibroadenoma, cyst, cystosarcoma phylloides, mucinous carcinoma, high-density opaque (large and dense) (12 Dec 1998) |
| large calorie | The quantity of energy required to raise the temperature of 1 kg of water 1캜, more precisely from 14.5 |
| large, dense breast lesions | <radiology> Carcinoma, sarcoma, cystosarcoma phylloides, cyst, abscess, lymph nodes (lymphoma, leukaemia, metastasis) (12 Dec 1998) |
| large gallbladder | <radiology> Courvoisier phenomenon, neoplasm of pancreatic head, distal common bile duct, papilla, hydrops, empyema, vagotomy, diabetes (20% of DM patients) Cf: small gall bladder (12 Dec 1998) |
| large-hearted | Having a large or generous heart or disposition; noble; liberal. Large"-heartedness. Source: Websters Dictionary (01 Mar 1998) |
| large interarch distance | A large distance between the maxillary and mandibular arches; may also imply an excessive vertical dimension. Synonym: open bite. (05 Mar 2000) |
| large intestine | <anatomy> Also called the colon, this structure has 6 major divisions: caecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum. The total length is approximately 5 feet in the adult and it is responsible for forming, storing and expelling waste matter. (27 Sep 1997) |
| large muscle of helix | <anatomy> A narrow band of muscular fibres on the anterior border of the helix of the auricle arising from the spine and inserted at the point where the helix becomes transverse. Synonym: musculus helicis major, large muscle of helix. (05 Mar 2000) |