| IGLL | immunoglobulin lambda-like |
|---|---|
| La | labial; lambda; lambert; lanthanum |
| APV | abnormal posterior vector |
| AV | Adriamycin and vincristine; air velocity; allergic vasculitis; anteroventral; anteversion; anticipat... |
| AVA | activity vector analysis; antiviral antibody; aortic valve area; aortic valve atresia; arteriovenous... |
| ST-VM | ST vector magnitude |
|---|---|
| SVM | Support Vector Machine |
| AdV | adenovirus vector |
| VCG | vector cardiography |
| cloning, molecular | The insertion of recombinant DNA molecules from prokaryotic and/or eukaryotic sources into a replicating vehicle, such as a plasmid or virus vector, and the introduction of the resultant hybrid molecules into recipient cells without altering the viability of those cells. (12 Dec 1998) |
|---|---|
| cloning, organism | The formation of one or more genetically identical organisms derived by vegetative reproduction from a single cell. The source nuclear material can be embryo-derived, foetus-derived, or taken from an adult somatic cell. (12 Dec 1998) |
| molecular cloning | <molecular biology> The biological amplification of a specific DNA sequence through mitotic division of a host cell into which it has been transformed or transfected. (09 Oct 1997) |
| complementary DNA cloning | <molecular biology, technique> A lab technique where a double-stranded cDNA molecule (or dscDNA) is inserted into a cloning vector (another DNA molecule which will continue to be capable of replication after insertion of foreign material), so that the gene encoded by the cDNA can be expressed (transcribed and used) or so many copies of the gene can be made. (09 Oct 1997) |
| multiple cloning site | Region of a phage or plasmid vector that has been engineered to contain a series of restriction sites that are usually unique within the entire vector. This makes it particularly easy to insert or excise (subclone) DNA fragments. (18 Nov 1997) |
| positional cloning | Cloning a gene based simply on knowing its position in the genome without any idea of the function of that gene. Because this is the reverse of how things have been traditionally done, it has also been called reverse genetics. (12 Dec 1998) |
| self cloning | <molecular biology> Any system in which inappropriate cell types or organisms are eliminated because they possess some character that allows them to die or to remove themselves from the system. Thus a transfected cell with genetic material including a drug resistance marker will be self cloning in the presence of the drug and nontransfected cells will die. (18 Nov 1997) |
| dilution cloning | Cloning by diluting the cell suspension to the point at which the probability of there being more than one cell in the inoculum volume is small. Inevitably on quite a few occasions there will not be any cells. (18 Nov 1997) |
| directional cloning | DNA insert and vector molecules are digested with two different restriction enzymes to create noncomplementary sticky ends at either endof each restriction fragment. This allows the insert to be ligated tothe vector in a specific orientation and prevents the vector fromrecircularising. (09 Oct 1997) |
| DNA cloning | The use of DNA manipulation procedures to produce multiple copies of a single gene or segment of DNA. (12 Dec 1998) |
| expression cloning | <molecular biology> A vector that results in the expression of inserted DNA sequences when propagated in a suitable host cell, i.e. The protein coded for by the DNA is synthesised by the host's system. (06 Aug 1998) |
| biological vector | A vector, such as the Anopheles mosquito for malarial agents or the tsetse fly for agents of African sleeping sickness, in which the agent multiplies prior to being transmitted to another host. (05 Mar 2000) |
| radius vector | 1. <mathematics> A straight line (or the length of such line) connecting any point, as of a curve, with a fixed point, or pole, round which the straight line turns, and to which it serves to refer the successive points of a curve, in a system of polar coordinates. See Coordinate. 2. <astronomy> An ideal straight line joining the center of an attracting body with that of a body describing an orbit around it, as a line joining the sun and a planet or comet, or a planet and its satellite. Source: Websters Dictionary (01 Mar 1998) |
| vector | 1. <mathematics> A term to describe something that has both direction and magnitude. 2. <molecular biology> Commonly term for a plasmid that can be used to transfer DNA sequences from one organism to another. Different vectors may have properties particularly appropriate to give protein expression in the recipient or for cloning or may have different selectable markers. Recombinant DNA systems especially suited for production of large quantities of specific proteins in bacterial, yeast, insect, or mammalian cell systems. See: transfection. (05 Mar 2000) |
| vector-borne | Denoting a disease or infection that is transmitted by an invertebrate vector. (05 Mar 2000) |