| 영문 | fibrinoid necrosis | 한글 | 섬유소성괴사 |
|---|---|---|---|
| 설명 | 초기의 류마티스 혹은 악성종양 등에서 볼 수 있는 혈관-결합조직의 특유한 변화로 혈관벽이나 주위의 결합조직이 섬유소모양으로 균질한 물질로 되고, 호산성으로 염색된다. 이것은 섬유소와 거의 똑같은 염색성을 나타내기 때문에 염증에서 혈관으로부터 섬유소 또는 섬유소모양의 물질이 삼출하여 결합조직 섬유간에 침착하여 구조가 불명료한 것으로 생각되었으나, 최근 조직화학, 전자현미경 등에 의하여 결합섬유자체에도 변화가 있는 것으로 면역글로불린의 침착도 증명되고 있다. |
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| 영문 | coagulation necrosis | 한글 | 응고괴사 |
|---|---|---|---|
| 설명 | 세포의 죽음을 나타내는 형태학적 변화로서 괴사부위가 응고한 상태로 있는 것. 괴사세포는 호산성 덩어리로 보이며 적어도 수일간 세포의 기본 윤곽이 보존되기 때문에 조직구조를 식별할 수 있다. 대표적으로 허혈괴사를 들 수 있다. 경색과 허혈에 의한 저산소증시 심장근이나 콩팥에서 관찰되거나 전기 및 수은중독시 콩팥의 요세관에서 관찰되는 것으로 단백의 변성 후 남아있기 때문이다. 세포의 윤곽이 남아 있어 원래 조직의 구조를 형태학적으로 인식할 수 있는 것이 특징이다. |
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| 영문 | caseation necrosis | 한글 | 치즈괴사, 건락괴사 |
|---|---|---|---|
| 설명 | 조직이 치즈와 같이 건조하고, 형태가 없는 덩어리로 변화하는 것으로 결핵감염 병터에서 볼 수 있는 독특한 괴사의 하나이다. |
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| SHN | spontaneous hemorrhagic necrosis; subacute hepatic necrosis |
|---|---|
| CK | calf kidney; casein kinase; chicken kidney; cholecystokinin; choline kinase; contralateral knee; cre... |
| DK | dark; decay; diabetic ketoacidosis; diet kitchen; diseased kidney; dog kidney [cells] |
| KT | kidney transplant, kidney transplantation |
| PKD | polycystic kidney disease; proliferative kidney disease |
| cerebrocortical necrosis | A noninfectious disease of ruminants characterised by a tissue-thiamine deficiency and by amaurosis and strabismus, followed by recumbency, opisthotonos, and convulsions. Synonym: cerebrocortical necrosis. (05 Mar 2000) |
|---|---|
| retinal necrosis syndrome, acute | <ophthalmology> Mild to fulminant necrotizing vaso-occlusive retinitis associated with a high incidence of retinal detachment and poor vision outcome. (12 Dec 1998) |
| coagulation necrosis | A type of necrosis in which the affected cells or tissue are converted into a dry, dull, fairly homogeneous eosinophilic mass without nuclear staining, as a result of the coagulation of protein as occurs in an infarct; microscopically, the necrotic process involves chiefly the cells, and remnants of histologic elements (e.g., elastin, collagen, muscle fibres) may be recognizable, as well as "ghosts" of cells and portions of cell membranes; may be caused by heat, ischemia, and other agents that destroy tissue, including enzymes that would continue to alter the devitalised cellular substance. (05 Mar 2000) |
| colliquative necrosis | An obsolete term for liquefactive necrosis. (05 Mar 2000) |
| mummification necrosis | A form of gangrene in which the involved part is dry and shriveled. Synonym: cold gangrene, mummification necrosis, mummification. (05 Mar 2000) |
| contraction band necrosis | A microscopic change in myocardial cells in which excessive contraction, associated with elevated intracellular calcium and serum norepinephrine, causes the formation of transverse amorphous band's in the fibres which are then incapable of contracting again. Synonym: contraction band necrosis. (05 Mar 2000) |
| myocardial necrosis | Irreversible destruction of myocardial (heart muscle) cells. (27 Sep 1997) |
| postpartum pituitary necrosis syndrome | <syndrome> Hypopituitarism arising from a severe circulatory collapse postpartum, with resultant pituitary necrosis. Synonym: postpartum pituitary necrosis syndrome, thyrohypophysial syndrome. (05 Mar 2000) |
| cystic medial necrosis | Loss of elastic and muscle fibres in the aortic media, with accumulation of mucopolysaccharide, sometimes in cystlike spaces between the fibres; a disease of unknown cause, which may be inherited and which predisposes to dissecting aneurysms. Synonym: Erdheim disease, medionecrosis aortae idiopathica cystica, medionecrosis of the aorta, mucoid medial degeneration. (05 Mar 2000) |
| progressive emphysematous necrosis | <microbiology> A severe form of gangrene (tissue necrosis) caused by Clostridium infection. Also referred to as necrotising subcutaneous infection. Results in death of the subcutaneous tissues and muscle layers. See: necrotising fascitis. (27 Sep 1997) |
| hepatic necrosis | A severe and rapidly progressive form of hepatitis accompanied by hepatocellular death and the signs and symptoms of hepatic failure. May be a complication of hepatitis B, C or D. (27 Sep 1997) |
| simple necrosis | A stage of coagulation necrosis; the occurrence of a coarsely granular or hyaline change in the cytoplasm, and the lack of a recognizable nucleus, with the general configuration of the dead cells being relatively unchanged. (05 Mar 2000) |
| necrosis | <pathology> The sum of the morphological changes indicative of cell death and caused by the progressive degradative action of enzymes, it may affect groups of cells or part of a structure or an organ. Origin: Gr. Nekrosis = deadness (18 Nov 1997) |
| necrosis bacillus | A species of gram-negative, non-spore-forming bacteria isolated from the natural cavities of man and other animals and from necrotic lesions, abscesses, and blood. (12 Dec 1998) |
| subcutaneous fat necrosis of newborn | Indurated plaques and nodules appearing usually a few days or a few weeks after birth and usually resolving within a few months, characterised microscopically by birefringent needle-shaped crystals within necrotic fat cells; the condition remains localised, unlike sclerema neonatorum. (05 Mar 2000) |