| RAEB-T | Refractory Anemia with Excess Blasts in Transformation |
|---|---|
| ATZ | atypical transformation zone |
| ELECTZ | electrosurgical loop excision of the cervical transformation zone |
| HLT | heart-lung transplantation; human lipotropin; human lymphocyte transformation |
| LETS | large external transformation-sensitive [protein] |
| germ line transformation | Micro injection of foreign DNA into an early embryo, so that it becomes incorporated into the germ line of the individual and thus stably inherited in subsequent generations of transgenic organisms. Typically, the DNA would be a reporter gene or cDNA in a vector such as a transposon, that might also carry a visible marker gene such as eye or coat colour), so that successful transformation could readily be detected. (18 Nov 1997) |
|---|---|
| viral transformation | <oncology, virology> Malignant transformation of an animal cell in culture, induced by a virus. (18 Nov 1997) |
| cell transformation | Morphological and physiological changes resulting from infection of an animal cell by an oncogenic virus. (05 Mar 2000) |
| cell transformation, neoplastic | Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill. (12 Dec 1998) |
| cell transformation, viral | An inheritable change in cells manifested by changes in cell division and growth and alterations in cell surface properties. It is induced by infection with a transforming virus. (12 Dec 1998) |
| Haldane transformation | The multiplication of inspired oxygen concentration by the ratio of expired to inspired nitrogen concentrations in the calculation of oxygen consumption or respiratory quotient by the open circuit method. (05 Mar 2000) |
| sol gel transformation | Transition between more fluid cytoplasm (endoplasm) and stiffer gel like ectoplasm proposed as a mechanism for amoeboid locomotion: since the endoplasm cannot really be considered a simple fluid and has visco elastic properties like a gel, the term is misleading. (18 Nov 1997) |
| spontaneous transformation | Transformation of a cultured cell that occurs without the deliberate addition of a transforming agent. Cells from some species, especially rodents, are particularly prone to such spontaneous transformation. (18 Nov 1997) |
| nodular transformation of the liver | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| transformation | <chemistry> The change of form or structure, conversion from one form to another. <oncology> The change that a normal cell undergoes as it becomes malignant. In eukaryotes, the conversion of normal cells to malignant cells in cell culture. Origin: L. Formatio = formation (18 Nov 1997) |
| transformation, bacterial | The heritable modification of the properties of a competent bacterium by DNA from another bacterial strain. (12 Dec 1998) |
| transformation constant | <physics, radiobiology> The fraction of the amount of a radionuclide that undergoes transition per unit time. Formally: Lamda=dP/dt Where dP is the probability of a given nucleus undergoing spontaneous nuclear transition in the time interval dt. (16 Dec 1997) |
| transformation efficiency | The number of bacterial cells that uptake and express plasmid DNA divided by the mass of plasmid used (in transformants/microgram). (09 Oct 1997) |
| transformation, genetic | The unidirectional transfer and incorporation of foreign DNA by prokaryotic or eukaryotic cells and the subsequent recombination of part or all of that DNA into the cell's genome. (glossary of genetics: classical and molecular, 5th ed) (12 Dec 1998) |
| transformation zone | Zone on the cervix at which squamous epithelium and columnar epithelium meet; changes location in response to a woman's hormonal status. (05 Mar 2000) |