| IBC | Institutional Biosafety Committee; iodine-binding capacity; iron-binding capacity; isobutyl cyanoacr... |
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| FABP | fatty acid-binding protein; folate-binding protein |
| PBP | penicillin-binding protein; porphyrin biosynthesis pathway; prostate-binding protein; pseudobulbar p... |
| RBP | retinol-binding protein; riboflavin-binding protein |
| SBP | schizobipolar; serotonin-binding protein; spontaneous bacterial peritonitis; steroid-binding plasma ... |
| GTP-binding protein | <molecular biology, protein> There are two main classes of G-proteins, the heterotrimeric G proteins that associate with receptors of the seven transmembrane domain superfamily and are involved in signal transduction and the small cytoplasmic G-proteins. Regulatory proteins found in all cells. They are versatile molecular switches, involved in the control of a wide range of biological processes - protein synthesis, signal transduction pathways, growth and differentiation. They all act through a common molecular mechanism based on their ability to bind the guanine nucleotides GTP and GDP selectively and with high affinity. Stimulatory G-proteins are permanently activated by cholera toxin, inhibitory ones by pertussis toxin. Transducin was one of the first of the heterotrimeric G-proteins to be identified. The small G-proteins are a diverse group of monomeric GTPases that include ras, rab, rac and rho and that play an important part in regulating many intracellular processes including cytoskeletal organisation and secretion. Their GTPase activity is regulated by activators (GAPs) and inhibitors (GIPs) that determine the duration of the active state. (12 Jul 2000) |
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| guanosine triphosphate binding protein | <protein> A type of protein embedded in the cytoplasmic membrane of the cell which transmits signals from outside the cell (such as from hormones binding to receptors on the outside of the cell) to the inside of the cell, where it causes some sort of biochemical reaction within the cell to the signal (such as the altering of metabolic pathways or gene expression). The process by which the protein does this is unclear but involves exchanging a molecule of GDP for a molecule of GTP. (09 Oct 1997) |
| placental calcium-binding protein | <protein> Calcium binding protein of placenta, uterus and vasculature containing the EF hand motif. (18 Nov 1997) |
| corticosteroid-binding protein | <chemical> Chemical name: Transcortins (12 Dec 1998) |
| protein binding | The process in which substances, either endogenous or exogenous, bind to proteins, peptides, enzymes, protein precursors, or allied compounds. Specific protein-binding measures are often used as assays in diagnostic assessments. (12 Dec 1998) |
| serotonin-binding protein kinase | <enzyme> An aspect of protein kinases EC 2.7.1.37 Registry number: EC 2.7.1.- Synonym: sbp kinase (26 Jun 1999) |
| single stranded binding protein | <protein> SSB's are proteins responsiblefor holding the replication fork of DNAopen while polymerases readthe templates. (09 Oct 1997) |
| Nuclear actin binding protein | <molecular biology> Nuclear protein, dimer of 34 kD subunits. Binds actin with Kd of around 25M. (18 Nov 1997) |
| DNA binding protein | <molecular biology> Proteins that interact with DNA, typically to pack or modify the DNA for example histones or to regulate gene expression, transcription factors. Among those proteins that recognise specific DNA sequences, there are a number of characteristic conserved motifs believed to be essential for specificity. (18 Nov 1997) |
| DNA-binding protein, cyclic AMP-responsive | A protein that has been shown to function as a calcium regulated transcription factor as well as a substrate for depolarisation-activated calcium calmodulin-dependent protein kinases I and II. This protein functions to integrate both calcium and camp signals. (12 Dec 1998) |
| insulin-like growth-factor binding protein 1 | One of the six homologous proteins that specifically bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions. The function of this protein is not completely defined. However, several studies demonstrate that it inhibits igf binding to cell surface receptors and thereby inhibits igf-mediated mitogenic and cell metabolic actions. (proc soc exp biol med 1993;204(1):4-29) (12 Dec 1998) |
| insulin-like growth factor-binding protein 2 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin-like growth factor binding protein 3 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin like growth-factor-binding protein 4 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |
| insulin-like growth-factor-binding-protein 5 | One of the six homologous soluble proteins that bind insulin-like growth factors (somatomedins) and modulate their mitogenic and metabolic actions at the cellular level. (12 Dec 1998) |