| sertoli cell tumour | A rare benign tumour of the testis that histologically resembles the foetal testis. There are three varieties: diffuse stromal, mixed (stromal and epithelial), and tubular (epithelial). Sertoli cells in the epithelial elements may produce oestrogen and cause feminization. (12 Dec 1998) |
|---|---|
| sertoli-leydig cell tumour | An ovarian tumour usually of low-grade malignancy occurring most frequently in the third and fourth decades, with 75% seen in women under 40. It is rare, representing less than .02% of ovarian cancers. The tumour typically produces androgens with virilization being noted in 70-85% of the patients. (holland et al., cancer medicine, 3d ed, p1684) (12 Dec 1998) |
| ovarian granulosa-theca cell tumour | <radiology> Any age, most benign, oestrogens may lead to isosexual precocious puberty (pathognomonic), large tumour with areas of cystic degeneration (12 Dec 1998) |
| theca cell tumour | A sex cord-stromal tumour of the postmenopausal ovary that is yellow, large, and unilateral, composed of fascicles of lipid-rich spindle cells interspersed with collagen, reticulin fibres, and hyaline plaques. Thecomas and other oestrogen-producing tumours (e.g., granulosa cell tumours) may induce adenomatous hyperplasia of the endometrium or well-differentiated endometrial carcinoma in 3%-20% of the cases. (12 Dec 1998) |
| tumour cell | <oncology> Cell derived from a tumour in an animal. Refers to a tumour causing malignant cell and not an adventitious normal cell. Loosely, a transformed cell able to give rise to tumours. (18 Nov 1997) |
| tumour stem cell assay | <investigation> A cytologic technique for measuring the functional capacity of tumour stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agent. (12 Dec 1998) |
| leydig cell tumour | The most common nongerminal tumour of the testis, derived from the leydig cells. It is rarely malignant. This tumour appears among 1-3% of testicular tumours and although they may be seen in children, the median age of appearance is 60 years. They are sometimes seen in women as ovarian tumours. Clinically, symptoms are usually related to the endocrine abnormalities induced by this tumour. (12 Dec 1998) |
| anterior border of testis | An imaginary convex line demarcating the lateral and medial surfaces. Synonym: margo anterior testis. (05 Mar 2000) |
| appendix of the testis | A vesicular nonpedunculated structure attached to the cephalic pole of the testis; a vestige of the cephalic end of the paramesonephric (mullerian) duct. Synonym: appendix testis, appendix of the testis, nonpedunculated hydatid, ovarium masculinum, sessile hydatid. (05 Mar 2000) |
| appendix testis | A small solid projection of tissue on the outer surface of the testis which is a remnant of the embryologic mullerian duct. (12 Dec 1998) |
| blood-testis barrier | The membrane in the testis that separates sperm from the bloodstream. (09 Oct 1997) |
| vaginal process of testis | A peritoneal diverticulum in the embryonic lower anterior abdominal wall that traverses the inguinal canal; in the male it forms the tunica vaginalis testis and normally loses its connection with the peritoneal cavity; a persistent processus vaginalis in the female is known as the canal of Nuck. Synonym: Nuck's diverticulum, processus vaginalis peritonei, vaginal process of peritoneum, vaginal process of testis. (05 Mar 2000) |
| vanished testis syndrome | <syndrome> Absence of both testes in a male with normal chromosomes (XY) and otherwise normal genitalia at birth and during childhood. Testes were present in at least the first trimester of gestation, but vanished sometime thereafter. (05 Mar 2000) |
| margo anterior testis | An imaginary convex line demarcating the lateral and medial surfaces. Synonym: margo anterior testis. (05 Mar 2000) |
| margo posterior testis | The rounded posterior portion of the testis into which the vessels enter. Synonym: margo posterior testis. (05 Mar 2000) |