| infantile cortical hyperostosis | Neonatal subperiosteal bone formation over many bones, especially the mandible and clavicles and the shafts of long bones; it follows fever, usually appearing before 6 months of age and disappearing during childhood. Synonym: Caffey's disease, Caffey's syndrome, Caffey-Silverman syndrome. (05 Mar 2000) |
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| infantile digital fibromatosis | Multiple fibrous flesh-coloured nodules on the extensor aspect of the terminal phalanges of adjacent digits of infants and young children which often recur after attempted excision, do not metastasize, and may spontaneously regress in two to three years; composed of spindle cells containing cytoplasmic inclusions believed to be derived from myofibrils. Synonym: infantile digital fibromatosis. (05 Mar 2000) |
| infantile diplegia | A type of cerebral palsy in which there is bilateral spasticity, with the lower extremities more severely affected. Compare: flaccid paralysis. Synonym: Erb-Charcot disease, infantile diplegia, Little's disease, spastic spinal paralysis, tabes spasmodica. (05 Mar 2000) |
| infantile dwarfism | 1. A state marked by slow development of mind and body. Synonym: infantile dwarfism. 2. Childishness, as characterised by a temper tantrum of an adolescent or adult. 3. Underdevelopment of the sexual organs. (05 Mar 2000) |
| infantile eczema | Eczema in infants; the clinical appearance varies according to the dominant causative mechanism, e.g., contact-type hypersensitivity, candidiasis, atopy, seborrhoea, or a combination including intertrigo and diaper dermatitis. (05 Mar 2000) |
| infantile fibrosarcoma | <tumour> A rapidly growing but infrequently metastasizing fibrosarcoma which usually appears on the extremities in the first year of life. (05 Mar 2000) |
| infantile gastroenteritis | An endemic viral gastroenteritis of young children (6 months to 12 years) that is especially widespread during winter, caused by strains of rotavirus; the incubation period is 2 to 4 days, with symptoms lasting 3 to 5 days, including abdominal pain, diarrhoea, fever, and vomiting. Synonym: infantile gastroenteritis. (05 Mar 2000) |
| infantile gastroenteritis virus | <virology> Genus of the Reoviridae having a double layered capsid and 11 double stranded RNA molecules in the genome. They have a wheel like appearance in the electron microscope and cause acute diarrhoeal disease in their mammalian and avian hosts. Probably the most important cause of severe dehydrating diarrhoea in children under three years of age worldwide. Symptoms include nausea, vomiting, low-grade fever and diarrhoea. Aggressive fluid replacement is generally required. (27 Sep 1997) |
| infantile generalised GM1 gangliosidosis | One of the hereditary metabolic diseases of infancy; resembles Tay-Sachs disease, except other organ systems (bone, liver, kidney) are affected. Synonym: familial neuroviscerolipidosis, pseudo-Hurler disease, Type 1 GM1 gangliosidosis. (05 Mar 2000) |
| infantile GM2 gangliosidosis | <disease> A genetic disorder found in east European Jewish families which can result in early death bu affecting the brain and nerves by causing abnormal lipid metabolism. It is a lysosomal disease in which there is a deficiency of hexosaminidase A, an enzyme that degrades ganglioside GM2. Symptoms appear at age 3-6 months and include blindness, deafness, seizures, paralysis, dementia, decreased muscle tone and growth retardation. There is no known treatment and most children usually die between 2 and 5 years of age. Inheritance: autosomal recessive. (06 Oct 1997) |
| infantile hemiplegia | Indefinite term for any motor abnormality in the infant caused by or attributed to the birthing process; includes obstetrical paralysis, infantile hemiplegia, etc. Synonym: infantile hemiplegia. (05 Mar 2000) |
| infantile hernia | A hernia in which an intestinal loop descends behind the tunica vaginalis, having, therefore, three peritoneal layers in front of it. (05 Mar 2000) |
| infantile hydrocephalus | <radiology> A VP-Shunt Can Decompress The Hydrocephalic Child, Aqueductal stenosis, Vein of Galen aneurysm, Postinfectious, Superior vena cava obstruction, Chiari malformation, Dandy-Walker syndrome, Tumour, Haemorrhage, Choroid plexus papilloma see: hydrocephalus (12 Dec 1998) |
| infantile hypothyroidism | <paediatrics> Stunted body growth and mental development appearing in the first years of life resulting the inappropriate development of the thymus gland or inadequate maternal intake of iodine during gestation. (27 Sep 1997) |
| infantile leishmaniasis | Visceral leishmaniasis in infants, from Leishmania donovani infantum. (05 Mar 2000) |