| 영문 | blood-brain barrier(BBB) | 한글 | 혈뇌장벽 |
|---|---|---|---|
| 설명 | 뇌와 척수에는 혈류로부터 어떤 물질이 유입되는 것을 막는 장벽이다. 이것은 뇌와 척수에 존재하는 모세혈관의 투과성이 비교적 다른 모세혈관의 투과성보다 떨어지기 때문이다. |
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| 영문 | blood-brain barrier | 한글 | 혈액뇌장벽 |
|---|---|---|---|
| 설명 | 혈액으로부터 뇌로는 지질용해성이 높은 약물밖에 이행되지 않는다. 수용성의 약물을 뇌로 이행되지 않게 하고 있는 것이 혈액뇌장벽이며 뇌의 모세혈관 내피세포, 모세혈관 주위의 세포가 장벽이 되고 있다. 물질교환은 수동확산에 의해 이루어지지만, 뇌의 생리적 활동에 필요한 물질은 이온형이라도 담체를 통해 이행된다. |
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| CIHS | central infantile hypotonic syndrome |
|---|---|
| CINCA | chronic infantile neurological cutaneous and auricular [syndrome] |
| EIEE | early infantile epileptic encephalopathy |
| FIMG | familial infantile myasthenia gravis |
| IA | ibotenic acid; immune adherence; immunoadsorbent; immunobiologic activity; impedance angle; indolami... |
| desmoplastic tumours | <radiology> Carcinoid of small bowel or colon, Hodgkin's lymphoma, scirrhous gastric carcinoma (12 Dec 1998) |
|---|---|
| duodenal tumours | <radiology> 90% benign, in 2nd and 3rd portion: 50% malignant, in 4th portion: most malignant, of malignancies: 80-90% leading to adenocarcinoma Differential diagnosis: benign, tubular adenoma, leiomyoma, lipoma, hamartoma (Peutz-Jeghers), prolapsed antral polyp, Brunner's gland adenoma (really hypertrophy and hyperplasia), malignant, adenocarcinoma (80-90% of malignant lesions), villous adenoma (pre-malignant), carcinoid / isleT-cell tumour (12 Dec 1998) |
| odontogenic tumours | Neoplasms produced from tooth-forming tissues. (12 Dec 1998) |
| ovarian stromal tumours | <radiology> Age 20 - 50 yrs, 20% of all ovarian tumours, fibroma / fibrosarcoma, granulosa-theca cell tumour, with or without oestrogens most likely to be precocious puberty, endometrial hyperplasia/carcinoma, fibrocystic breast disease, Sertoli-Leydig cell tumour, aka: arrhenoblastoma, with or without androgens most likely to be masculinization, may be mixed type (12 Dec 1998) |
| ovarian tumours | <radiology> Before age 45 most likely to be 98% benign, 2/3 of cancers in ages 40 - 65 yrs see also: ovarian stromal tumours (12 Dec 1998) |
| lymphatic vessel tumours | Neoplasms composed of lymphoid tissue, a lattice work of reticular tissue the interspaces of which contain lymphocytes. The concept does not refer to neoplasms located in lymphatic vessels. (12 Dec 1998) |
| aggressive infantile fibromatosis | A childhood counterpart of abdominal or extra-abdominal desmoid tumours, characterised by firm subcutaneous nodules that grow rapidly in any part of the body that invade locally and recur but do not metastasize. (05 Mar 2000) |
| autism, infantile | A syndrome beginning in infancy and characterised by a lack of responsiveness to other people, gross impairment in verbal and nonverbal communication skills, and bizarre responses to the environment. (12 Dec 1998) |
| progressive infantile spinal muscular atrophy | Transmitted as autosomal recessive on chromosome 5q. Progressive dysfunction of the anterior horn cells in the spinal cord and brainstem cranial nerves with profound weakness and bulbar dysfunction occurring in the first two years of life. Three groups, based on age of clinical onset, are recognised. Synonym: familial spinal muscular atrophy, Hoffmann's muscular atrophy, infantile muscular atrophy, infantile progressive spinal muscular atrophy, progressive infantile spinal muscular atrophy, Werdnig-Hoffmann disease, Werdnig-Hoffmann muscular atrophy. (05 Mar 2000) |
| spasms, infantile | Primary generalised epileptic seizures occurring in infants between birth and twelve months of age consisting of brief synchronous contractions of the neck, torso, and both arms. These seizures often occur in infants with underlying neurologic diseases. The prognosis for these infants is grave, with approximately ninety percent developing mental retardation in addition to their seizures. The eeg has a typical hypsarrhythmia pattern. The spasms and hypsarrhythmia have a tendency to disappear over the first three to five years of life, only to be replaced by other forms of generalised seizures. Infantile spasms sometimes respond to valproic acid or acth. (12 Dec 1998) |
| supravalvar aortic stenosis-infantile hypercalcaemia syndrome | <syndrome> Supravalvar aortic stenosis associated with elfin facies, mental retardation, and hypercalcaemia; usually sporadic; perhaps an irregular dominant trait. (05 Mar 2000) |
| diffuse infantile familial sclerosis | <radiology> Dysmyelinating disease, autosomal recessive, usually presents by 1 yr, specific enzyme deficiency identified, rapid spontaneous nystagmus, poikilothermia Synonym: Krabbe leukodystrophy (12 Dec 1998) |
| infantile | Pertaining to an infant or to infancy. Origin: L. Infantilis (18 Nov 1997) |
| infantile acute haemorrhagic oedema of the skin | A generally benign form of cutaneous vasculitis, characterised by ecchymotic purpura, often in a cockade pattern, and inflammatory oedema in infants. (05 Mar 2000) |
| infantile autism | A severe emotional disturbance of childhood characterised by qualitative impairment in reciprocal social interaction and in communication, language, and social development. Synonym: autistic disorder, childhood schizophrenia, early infantile autism, Kanner's syndrome. (05 Mar 2000) |