| 영문 | acid | 한글 | 산 |
|---|---|---|---|
| 설명 | 물에 녹았을 때 이온화하여 수소 이온을 만드는 물질. 신맛이 나고 청색 리트머스 종이를 붉게 변화시키며 염기와의 중화 반응에 의하여 물과 염을 만들고 이온화 열에서 수소보다 앞에 있는 금속과 반응하여 염을 만들면서 수소를 발생시킨다. 수소 원자를 이온화하는 힘의 강약에 따라 강산과 약산으로 나뉜다. |
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| 영문 | acetic acid | 한글 | 아세트산, 초산 |
|---|---|---|---|
| 설명 | 분자식은 C2H4O2, 분자량 60.05의 저급 지방산이다. CH3COOH의 구조식을 가진 무색액체로 16.7℃에서 녹고 118.0℃에서 끓는다. 식초의 신맛을 내는 것이고, 농축된 것을 빙초산이라 한다. 상온에서는 액체이며 수용액은 약산성이다. 생체내에서는 일반적으로 아세틸 CoA로 존재하며 아세틸기의 공급원이 되는 외에 지방산이나 스테로이드 등의 생성재료로 중요하다. 아세틸 CoA로부터는 케톤체가 합성되며 조직의 에너지원이 된다. |
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| 영문 | acetylsalicylic acid | 한글 | 아세틸살리실산 |
|---|---|---|---|
| 설명 | 상품명이 아스피린(asprin)인 약. 대표적인 비스테로이드 항염약이다. 즉 항염증(anti-inflammatory), 진통(analgesis), 해열(anti-pyretic)의 효과가 모두 뛰어나지만 위장장애, 과다호흡, 라이증후군(Reye syndrome) 등의 부작용이 있다. |
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| 영문 | uric acid | 한글 | 요산 |
|---|---|---|---|
| 설명 | 결정성의 산. 2, 6, 8-trioxypurine. 화학식은 C5H4N4O3로 사람과 동물의 오줌에서 얻을 수 있다. 핵의 대사산물의 하나. 물, 알콜, 에테르(ether)에는 거의 녹지 않으나 알칼리염의 용액에는 녹는다. 이것의 나트륨염 형태(sodium urate)가 결석의 대부분을 차지한다. 급성백혈병 치료 초기단계와 통풍(Gout)에서 혈중요산이 급격히 오를 수 있다. |
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| 영문 | acid-fast bacillus | 한글 | 항산막대균, 항산균 |
|---|---|---|---|
| 설명 | 아닐린 색소에 염색되기 힘드나 일단 염색되면 강산으로 처리하여도 탈색되지 아니하는 세균을 통틀어 이르는 말. 결해균, 나병균 따위가 있다. |
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| nucleic acid probes | Nucleic acid which complements a specific mRNA or DNA molecule, or fragment thereof; used for hybridization studies in order to identify microorganisms and for genetic studies. (12 Dec 1998) |
|---|---|
| nucleic acid renaturation | The reformation of all, or part of, the native conformation of a nucleic acid molecule after the molecule has undergone denaturation. (12 Dec 1998) |
| nucleic acid synthesis inhibitors | Compounds that inhibit cell production of DNA or RNA. (12 Dec 1998) |
| adenocarcinoma in situ | A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma; reported in the endometrium, large intestine, cervix, and other sites. (05 Mar 2000) |
| carcinoma in situ | Cancer that involves only the cells in which it began and has not spread to other tissues. Lobular carcinoma in situ is found in the lobules of the breast. Ductal carcinoma in situ (also called intraductal carcinoma) arises in the ducts. (16 Dec 1997) |
| malignant melanoma in situ | A melanoma limited to the epidermis and composed of nests of atypical melanocytes and scattered single cells extending into the upper epidermis; local excision is curative although the lesion, if untreated, may soon invade the dermis. Malignant lentigo may be considered a slowly progressive type of malignant melanoma in situ. (05 Mar 2000) |
| ductal carcinoma in situ | <oncology, tumour> A cancer inside the ducts of breast that has not grown through the wall of the duct into the surrounding tissues. Sometimes referred to as a precancer. Good prognosis is involved with in situ cancers. (09 Oct 1997) |
| in situ | In the natural or normal place, confined to the site of origin without invasion of neighbouring tissues. (18 Nov 1997) |
| in situ hybridisation | <molecular biology, technique> Use of a DNA or RNA probe todetect the presence of the complementaryDNA sequence in cloned bacterial or cultured eukaryotic cells.Also used for locating geneson chromosomes. The process is: Prepare microscope slide with cells in metaphase of mitosis, Treat slide with a weak base. Thus denaturing the DNA. Pour radioactively labelled probe onto the slide. Expose slide to photographic emulsion for a few days or weeks. Develop emulsion. (13 Oct 1997) |
| lobular carcinoma in situ | <tumour> Carcinoma of the breast in which small tumour cells fill preexisting acini within lobules, without invading the surrounding stroma. Synonym: lobular carcinoma in situ, lobular neoplasia. (05 Mar 2000) |
| cell hybridization | Fusion of two or more dissimilar cells, leading to formation of a synkaryon. (05 Mar 2000) |
| cross hybridization | Annealing of a DNA probe to an imperfectly matching DNA molecule. (05 Mar 2000) |
| protein hybridization | The formation of a protein consisting of two or more polypeptide chains from separate and different polypeptide chains. (12 Dec 1998) |
| hybridization | <molecular biology> The process of joining two complementary strands of DNA or one each of DNA and RNA to form a double-stranded molecule. Technique in which single stranded nucleic acids are allowed to interact so that complexes or hybrids, are formed by molecules with sufficiently similar, complementary sequences. By this means the degree of sequence identity can be assessed and specific sequences detected. The hybridisation can be carried out in solution or with one component immobilised on a gel or, most commonly, nitrocellulose paper. Hybrids are detected by various means: visualisation in the electron microscope, by radioactively labelling one component and removing noncomplexed DNA or by washing or digestion with an enzyme that attacks single stranded nucleic acids and finally estimating the radioactivity bound. Hybridisations are done in all combinations: DNA DNA (DNA can be rendered single stranded by heat denaturation), DNA RNA or RNA RNA. In situ hybridisations involve hybridising a labelled nucleic acid (often labelled with a fluorescent dye) to suitably prepared cells or histological sections. This is used particularly to look for specific transcription or localisation of genes to specific chromosomes (FISH analysis). <zoology> The mating of individuals from different species or sub-species. (13 Oct 1997) |
| somatic cell hybridization | Production of a heterokaryon. (05 Mar 2000) |