| DMI | Defense Mechanism Inventory; Diagnostic Medical Instruments; diaphragmatic myocardial infarction; di... |
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| FM | face mask; facilities management; family medicine; feedback mechanism; fetal movement; fibromuscular... |
| IDM | idiopathic disease of myocardium; immune defense mechanism; indirect method; infant of diabetic moth... |
| IRM | innate releasing mechanism; Institute of Rehabilitation Medicine |
| MoA | mechanism of action |
impedence test
| random mechanism | A scheme for substrate binding and product release for a multisubstrate enzyme; for a two-substrate two-product enzyme with this mechanism, either substrate can bind first and, after the reaction has taken place, either product can be the first to dissociate from the enzyme. Brain hexokinase has a random mechanism. More complex random mechanisms exist for enzymes having more than two substrates. (05 Mar 2000) |
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| cassette mechanism | <molecular biology> Term used for genes such as the a and _ genes that determine mating type in yeast, either one or the other is active. In this gene conversion process, a double stranded nuclease makes a cut at a specific point in the MAT locus, the old gene is replaced with a copy of a silent gene from one or other flanking region and the new copy becomes active. As the process involves replacing one ready made construct with another in an active slot it is called a cassette mechanism. (18 Nov 1997) |
| re-entrant mechanism | The probable basis of most arrhythmias, requiring at least three criteria in the heart: 1. A loop circuit, 2. Unidirectional block, 3. Slowed conduction. Impulses enter the loop circuit and divide in both directions (blocked in one direction only), negotiate the loop circuit to the area of block where the slowed conduction has allowed the impulse to arrive at a time when the tissue proximal to the unidirectional block has recovered and will permit its passage in the opposite direction. (05 Mar 2000) |
| mechanism | The manner of combination of parts, processes, etc., which subserve a common function. Origin: Gr. Mechan = machine (18 Nov 1997) |
| mechanism-based inhibitor | A competitive inhibitor that is converted to an irreversible inhibitor at the active site of the enzyme. Synonym: mechanism-based inhibitor. (05 Mar 2000) |
| rolling circle mechanism | <molecular biology> A mechanism of DNA replication in many viral DNAs, in bacterial f factors during mating and of certain DNAs in gene amplification in eukaryotes. DNA synthesis starts with a cut in the + strand at the replication origin, the 5' end rolls out and replication starts at the 3' side of the cut around the intact circular DNA strand. Replication of the 5' end (tail) takes place by the formation of Okazaki fragments. (18 Nov 1997) |
| ping-pong mechanism | A special multisubstrate reaction in which, for a two-substrate, two-product (i.e., bi-bi) system, an enzyme reacts with one substrate to form a product and a modified enzyme, the latter then reacting with a second substrate to form a second, final product, and regenerating the original enzyme. An example of such a mechanism is found in the aminotransferases. More complex ping-pong mechanisms exist for enzymes having more than two substrates. Synonym: double displacement mechanism. (05 Mar 2000) |
| countercurrent mechanism | A system in the renal medulla that facilitates concentration of the urine as it passes through the renal tubules. See: countercurrent exchanger, countercurrent multiplier. (05 Mar 2000) |
| pressoreceptive mechanism | The pressoreceptor system, especially of the carotid sinuses and aortic arch. (05 Mar 2000) |
| proprioceptive mechanism | <physiology> The mechanism of sense of position and movement, by which muscular movements can be adjusted to a great degree of accuracy and equilibrium maintained. (05 Mar 2000) |
| Schultze's mechanism | Expulsion of the placenta with the foetal surface foremost. (05 Mar 2000) |
| defense mechanism | A psychological means of coping with conflict or anxiety, e.g., conversion, denial, dissociation, rationalization, repression, sublimation, the psychic structure underlying a coping strategy, immunological mechanism vs. Non-specific defense mechanism. (05 Mar 2000) |
| double displacement mechanism | A special multisubstrate reaction in which, for a two-substrate, two-product (i.e., bi-bi) system, an enzyme reacts with one substrate to form a product and a modified enzyme, the latter then reacting with a second substrate to form a second, final product, and regenerating the original enzyme. An example of such a mechanism is found in the aminotransferases. More complex ping-pong mechanisms exist for enzymes having more than two substrates. Synonym: double displacement mechanism. (05 Mar 2000) |
| Douglas mechanism | Mechanism of spontaneous evolution in transverse lie; extreme lateral flexion of the vertebral column with birth of the lateral aspect of thorax before the buttocks. (05 Mar 2000) |
| Duncan's mechanism | Passage of the placenta from the uterus with the rough side foremost. (05 Mar 2000) |