| immunological paralysis | Lack of specific antibody production after exposure to large doses of the antigen; immunological paralysis disappears when the antigen is eliminated. See: immunologic tolerance. (05 Mar 2000) |
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| immunological surveillance | <immunology> The hypothesis that lymphocyte traffic ensures that all or nearly all parts of the vertebrate body are surveyed by visiting lymphocytes in order to detect any altered self material, for example mutant cells. (18 Nov 1997) |
| immunological tolerance | <immunology> Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under conditions in which specific clones are suppressed. Note that tolerance is not the same as immunological unresponsiveness, since the latter may be very non-specific as in immunodeficiency states. (18 Nov 1997) |