| immunological disease | <immunology> Any illness, such as an allergy, that is caused by the action of antibodies. (09 Oct 1997) |
|---|---|
| immunological enhancement | In immunology, the potentiating effect of specific antibody in establishing and in delaying rejection of a tumour allograft; aside from antibody, non-specific substances may also act to enhance immune response. Synonym: immunological enhancement. (05 Mar 2000) |
| immunological mechanism | The groups of cells (chiefly lymphocytes and cells of the reticuloendothelial system) that function in establishing active acquired immunity (induced sensitivity, allergy). (05 Mar 2000) |
| immunological memory | <immunology> The systems responsible for the situation where reactions to a second or subsequent exposure to an antigen are more extensive than those seen on first exposure (but See immunological tolerance. The memory is best explained by clonal expansion and persistence of such clones following the first exposure to antigen. (18 Nov 1997) |
| immunological network | <immunology> The concept due to Jerne that the entire specific immune system within an animal is made up of a series of interacting molecules and cell surface receptors, based on the idea that every antibody combining site carries its own marker antigens or idiotypes and that these in turn may be recognised by another set of antibody combining sites and so on. (18 Nov 1997) |
| immunological paralysis | Lack of specific antibody production after exposure to large doses of the antigen; immunological paralysis disappears when the antigen is eliminated. See: immunologic tolerance. (05 Mar 2000) |
| immunological surveillance | <immunology> The hypothesis that lymphocyte traffic ensures that all or nearly all parts of the vertebrate body are surveyed by visiting lymphocytes in order to detect any altered self material, for example mutant cells. (18 Nov 1997) |
| immunological tolerance | <immunology> Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under conditions in which specific clones are suppressed. Note that tolerance is not the same as immunological unresponsiveness, since the latter may be very non-specific as in immunodeficiency states. (18 Nov 1997) |
| immunologically activated cell | An immunocyte that is in an elevated state of reactivity capable of carrying out an immune response, in contradistinction to an immunologically competent cell. (05 Mar 2000) |
| immunologically competent cell | A small lymphocyte capable of being immunologically activated by exposure to a substance that is antigenic (immunogenic) for the respective cell; activation involves either the capacity to produce antibody or the capacity to participate in cell-mediated immunity. (05 Mar 2000) |
| immunologically privileged sites | Sites where allografts are not readily rejected, probably because these particular areas have poor lymphatic drainage. (05 Mar 2000) |