| BFR | biologic false reaction; blood flow rate; bone formation rate; buffered Ringer [solution] |
|---|---|
| DMRF | dorsal medullary reticular formation |
| ECF | effective capillary flow; eosinophilic chemotactic factor; erythroid colony formation; extended care... |
| LPF | leukocytosis-promoting factor; leukopenia factor; lipopolysaccharide factor; localized plaque format... |
| PPRF | paramedian pontine reticular formation; postpartum renal failure |
| genes, immunoglobulin | Genes encoding the light and heavy chain segments of immunoglobulins. Light chain gene segments are symbolised l-v (variable), j (joining) and c (constant); ig heavy chain segments have, in addition, a diversity (d) gene. Each segment codes for certain amino acids, and each has a different nucleotide sequence; the genes are assembled by a remarkable shuffling of the segments during b lymphocyte maturation. (12 Dec 1998) |
|---|---|
| receptors, polymeric immunoglobulin | Specialised fc receptors (receptors, fc) for polymeric immunoglobulins, which mediate transcytosis of polymeric IgA and IgM into external secretions. They are found on the surfaces of epithelial cells and hepatocytes. After binding to IgA, the receptor-ligand complex undergoes endocytosis, transport by vesicle, and secretion into the lumen by exocytosis. Before release, the part of the receptor (secretory component) that is bound to IgA is proteolytically cleaved from its transmembrane tail. (12 Dec 1998) |
| measles immunoglobulin | measles immune globulin (human) |
| cellular immunodeficiency with abnormal immunoglobulin synthesis | An ill-defined group of sporadic disorders of unknown cause, occurring in both males and females and associated with recurrent bacterial, fungal, protozoal, and viral infections; there is thymic hypoplasia with depressed cellular (T-lymphocyte) immunity combined with defective humoral (B-lymphocyte) immunity, although immunoglobulin levels may be normal. Synonym: Nezelof syndrome, Nezelof type of thymic alymphoplasia. (05 Mar 2000) |
| Rho(D) immunoglobulin | rHo(D) immune globulin |
| chickenpox immunoglobulin | chickenpox immune globulin (human) |
| pertussis immunoglobulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| monoclonal immunoglobulin | A homogenous immunoglobulin resulting from the proliferation of a single clone of plasma cells and which, during electrophoresis of serum, appears as a narrow band or "spike"; it is characterised by heavy chains of a single class and subclass, and light chains of a single type. Synonym: M protein, monoclonal protein, paraprotein. (05 Mar 2000) |
| poliomyelitis immunoglobulin | poliomyelitis immune globulin (human) |
| secretory immunoglobulin | Usually IgA but may be IgM linked to a secretory component and found in mucous secretions. (05 Mar 2000) |
| secretory immunoglobulin A | A subclass of IgA that is found primarily in secretions such as tears and colostrum. This form of IgA is protected from proteolytic degradation by the presence of a secretory component. (05 Mar 2000) |
| selective immunoglobulin A deficiency | <immunology> An inherited disorder in which there is a markedly reduced or absent IgA, resulting in immature IgA-bearing B-cells. (05 Mar 2000) |
| human normal immunoglobulin | A preparation of the proteins of liquid human plasma, containing the antibodies of normal adults; it is obtained from pooled liquid human plasma from a number of donors and may be prepared by precipitation with organic solvents under controlled conditions of pH, ionic strength, and temperature. Synonym: human normal immunoglobulin. (05 Mar 2000) |
| serum immunoglobulin electrophoresis | A test that detects and measures the various immunoglobulins in the blood. In the normal assay no monoclonal antibodies are detected. In multiple myeloma and chronic lymphocytic leukaemia a single clone of lymphocytes can produce one type of immunoglobulin that is detected in the electrophoresis as monoclonal (made by one cell clone). (27 Sep 1997) |
| immunoglobulin | <immunology> A specific protein substance that is produced by plasma cells to aid in fighting infection. Some immunoglobulins (gamma globulin) take part in various immune responses of the body to bacteria or foreign substances (allergens, tumour or transplanted tissue). Examples include IgG, IgM, IgA, IgD and IgE. (30 Mar 1998) |