| 영문 | aplastic anemia | 한글 | 재생불량빈혈 |
|---|---|---|---|
| 설명 | 재생불량성 빈혈이란 골수의 이상으로 생기는 빈혈이다. 골수란 뼈속에 존재하는 것으로 혈구를 생성하는 세포들과 미성숙한 혈구들로 이루어져 있다. 이것들이 여러 가지 원인에 의해서 파괴되었을 때 생기는 빈혈을 재생불량빈혈이라고 한다. 그러므로 적혈구만의 감소가 아니라 모든 혈구 세포의 감소를 볼 수 있다. 치료로는 혈구 생성을 자극하는 호르몬을 투여하는 것이 있지만 이것으로는 파괴된 혈구를 생성하는 세포의 재생이 일어나지 못하므로 완전한 치료라고는 볼 수가 없다. 완전한 치료로는 남의 골수를 채취해서 이것에서부터 혈구를 생성하는 세포를 분리, 환자에게 이식하는 골수이식이 있다. |
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| 영문 | iron deficiency anemia | 한글 | 철결핍빈혈 |
|---|---|---|---|
| 설명 | 적혈구의 기능은 산소를 운반하는데 있다. 적혈구 속에 산소와 결합을 하여 산소를 운반하는 혈색소라는 물질이 있다. 철은 이 혈색소의 중요한 부분을 이루는 것으로 철이 없으면 혈색소가 만들어질 수가 없다. 혈색소가 없으면 역시 적혈구도 만들어지지 않으므로 체내에 철이 부족하면 빈혈이 생긴다. 이 철결핍성 빈혈은 빈혈의 원인 중에서 가장 흔한 것이다(약 25%를 차지한다). 철저장량의 저하-결핍, 혈청철농도의 저하, 트란스페린량 상승, 트란스페린포화도의 저하, 혈색소농도 또는 헤마토크리트의 저하, 저색소성대적혈구를 특징으로 하는 빈혈로서, 생체 내에서 철이 장기에 걸쳐 결핍되며 그 때문에 혈색소 생산 감소에 의해 일어난다. 창자에서의 철흡수량 부족, 철의 수요 증대(유아기, 사춘기, 임신), 철소실과잉(출혈)에 의해 일어나며, 특히 사춘기에서 폐경기까지의 여성에게 많다. 증상으로서는 얼굴창백, 피로감, 피부창백, 손톱 변화(스푼 모양) 등을 나타낸다. 구강 영역에서는 혀의 접촉통, 발적, 건조감, 삼킴곤란을 수반하면 플러머-빈슨(Plummer-Vinson)증후군이라고 한다. 혈액 소견은 혈청철은 저하하며, 철결합능력의 상승, 저색소성 작은적혈구성을 나타낸다. |
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| CHA | Canadian Hospital Association; Catholic Health Association; Chinese hamster; chronic hemolytic anemi... |
|---|---|
| AIHD | acquired immune hemolytic disease |
| HIB | heart infusion broth; hemolytic immune body; Hemophilus influenzae type B [vaccine] |
| AHA | Autoimmune Hemolytic Anemia |
| HA | 1) Hemolytic Anemia 2) Head-Ache |
| humoral immune response | <immunology> Those immune responses mediated by antibody. (06 Mar 1998) |
|---|---|
| specific immune globulin | Globulin fraction of pooled serums (or plasma) selected for high titre of antibodies specific for a particular antigen, or from persons specifically immunised. (05 Mar 2000) |
| immune | <immunology> Protected against, infectious disease by either specific or non-specific mechanisms. Origin: L. Immunis = free, exempt (18 Nov 1997) |
| immune adherence | The binding of antigen-antibody complexes or cells coated with antibodies or complement to cells bearing the appropriate complement or Fc receptors. (05 Mar 2000) |
| immune adherence phenomenon | A phenomenon manifested by the adherence of antigen-antibody-complement complex to "indicator cells" (microorganisms, platelets, leukocytes, or erythrocytes), the reaction being sensitive and specific for the antigen and antibody in the complex. Synonym: erythrocyte adherence phenomenon, immune adherence phenomenon, red cell adherence phenomenon. (05 Mar 2000) |
| immune adherence reaction | A method for the detection of very small quantities of antibody in which the antigen-antibody-complement complex adheres to indicator cells, usually primate erythrocytes or nonprimate blood platelets. The reaction is dependent on the number of bound c3 molecules on the c3b receptor sites of the indicator cell. (12 Dec 1998) |
| immune adhesion test | The diagnostic application of the immune adhesion phenomenon. Synonym: erythrocyte adherence test, immune adhesion test, red cell adherence test. (05 Mar 2000) |
| immune adsorption | Removal of antibody (agglutinin or precipitin) from antiserum by use of specific antigen; after aggregation has occurred, the antigen-antibody complex is separated either by centrifugation or by filtration, removal of antigen by specific antiserum in a similar manner. (05 Mar 2000) |
| immune agglutination | Agglutination caused by antibody (agglutinin) that is specific for the suspended microorganism, cell, or for an antigen that has been coated on a particle of suitable size. (05 Mar 2000) |
| immune agglutinin | 1. An antibody that causes clumping or agglutination of the bacteria or other cells which either stimulated the formation of the agglutinin, or contain immunologically similar, reactive antigen. Synonym: agglutinating antibody, immune agglutinin. 2. A substance, other than a specific agglutinating antibody, that causes organic particles to agglutinate, commonly qualified, e.g., plant agglutinin. (05 Mar 2000) |
| immune complex | <immunology> Multimolecular antibody antigen complexes that may be soluble or insoluble depending upon their size and whether or not complement is present. Immune complexes can be filtered from plasma in the kidney and the deposition of the complexes gives rise to glomerulonephritis probably because of the trapping of neutrophils via their Fc receptors. (18 Nov 1997) |
| immune complex disease | An immunologic category of diseases evoked by the deposition of antigen-antibody or antigen-antibody-complement complexes on cell surfaces, with subsequent involvement of breakdown products of complement, platelets, and polymorphonuclear leukocytes, and development of vasculitis; nephritis is common. Arthus phenomenon and serum sickness are classic examples, but many other disorders, including most of the connective tissue disease's, may belong in this immunologic category; immune complex disease's can also occur during a variety of disease's of known aetiology, such as subacute bacterial endocarditis. See: autoimmune disease. Synonym: immune complex disorder, type III hypersensitivity reaction. (05 Mar 2000) |
| immune complex diseases | Diseases characterised by the presence of immune complexes in body fluids. Hypersensitivity of the Arthus type and serum sickness are examples. (18 Nov 1997) |
| immune complex disorder | An immunologic category of diseases evoked by the deposition of antigen-antibody or antigen-antibody-complement complexes on cell surfaces, with subsequent involvement of breakdown products of complement, platelets, and polymorphonuclear leukocytes, and development of vasculitis; nephritis is common. Arthus phenomenon and serum sickness are classic examples, but many other disorders, including most of the connective tissue disease's, may belong in this immunologic category; immune complex disease's can also occur during a variety of disease's of known aetiology, such as subacute bacterial endocarditis. See: autoimmune disease. Synonym: immune complex disorder, type III hypersensitivity reaction. (05 Mar 2000) |
| immune complex glomerulonephritis | Immune complexes are deposited in the renal glomerulus where they bind complement and initiate an inflammatory process attracting neutrophils and macrophages resulting in an alteration of the basement layer of the kidney. The disease state can lead to ultimate destruction of the glomerulus and renal failure. (05 Mar 2000) |