| indirect agglutination | Agglutination of particles that have been coated with soluble antigen, by antiserum specific for the adsorbed antigen. Synonym: indirect agglutination. (05 Mar 2000) |
|---|---|
| false agglutination | 1. Agglomeration of particles in solution which does not involve antigen-antibody combination. Synonym: false agglutination. Synonym: rouleaux formation. (05 Mar 2000) |
| latex agglutination | Also known as latex particle agglutination, for detection of antibodies is identical to haemagglutination in principle, but the substitution of smaller, antigen-coated latex particles for erythrocytes results in improved sensitivity and reagent longevity. Alternatively, antibodies can be absorbed to the latex particles (under appropriate ionic and pH conditions) by binding to the Fc region of antibodies, leaving the Fab region free to interact with antigens present in the applied specimens. This phenomenon has made latex agglutination a popular technique for detecting antigens as well. (05 Mar 2000) |
| latex agglutination test | A passive agglutination test in which antigen is adsorbed onto latex particles which then clump in the presence of antibody specific for the adsorbed antigen. Synonym: latex fixation test. (05 Mar 2000) |
| rabies immune globulin | Globulin fraction of pooled plasma of high anti-rabies virus titre from immunised persons. Synonym: rabies immunoglobulin. (05 Mar 2000) |
| measles immune globulin | A sterile solution of globulin's derived from the blood plasma of normal adult human donors; it is prepared from immune serum globulin that complies with the measles antibody reference standard; a passive immunizing agent. Synonym: measles immunoglobulin. (05 Mar 2000) |
| cellular immune theory | A concept, put forth by Elie Metchnikoff, that cells, not antibodies, were responsible for the immune response of an organism. (05 Mar 2000) |
| rho(d) immune globulin | Immunizing agent containing IgG anti-rho(d) used for preventing rh immunization in rh-negative individuals exposed to rh-positive red blood cells. (12 Dec 1998) |
| chickenpox immune globulin | Globulin fraction of serum from persons recently recovered from herpes zoster infection; used to prevent infection of high-risk children. Synonym: chickenpox immunoglobulin. (05 Mar 2000) |
| pertussis immune globulin | A sterile solution of globulin's derived from the plasma of adult human donors who have been immunised with pertussis vaccine; used both prophylactically and therapeutically. Synonym: pertussis immunoglobulin. (05 Mar 2000) |
| poliomyelitis immune globulin | A sterile solution of globulin's that contains those antibodies normally present in adult human blood; it is a passive immunologic agent that attenuates or prevents poliomyelitis, measles, and infectious hepatitis, and confers temporary but significant protection against paralytic polio. Synonym: poliomyelitis immunoglobulin. (05 Mar 2000) |
| primary immune response | <immunology> The immune response to the first challenge by a particular antigen. Usually less extensive than the secondary immune response, being slower and shorter lived with smaller amounts of lower affinity antibody being produced. (18 Nov 1997) |
| hemic and immune systems | The organs involved in the production and functions of the blood and the cellular and molecular components providing defense against foreign organisms or substances. (12 Dec 1998) |
| secondary immune response | The response of the immune system to the second or subsequent occasion on which it encounters a specific antigen. (18 Nov 1997) |
| human measles immune serum | Obtained from the blood of a healthy person who has survived an attack of measles. Synonym: measles convalescent serum. (05 Mar 2000) |