| IPF | Idiopathic Pulmonary Fibrosis |
|---|---|
| IAF | idiopathic alveolar fibrosis |
| IRF | idiopathic retroperitoneal fibrosis; impulse response function; interferon regulatory factor; intern... |
| PSS | painful shoulder syndrome; physiologic saline solution; porcine stress syndrome; primary Sjogren syn... |
| SMCD | senile macular choroidal degeneration; systemic mast cell disease; systemic meningococcal disease |
| cystic fibrosis antigen | Now known to be MRP 8. See: calgranulins. (18 Nov 1997) |
|---|---|
| cystic fibrosis transmembrane conductance regulator | Gene believed to be defective in cystic fibrosis. Gene encodes a chloride channel, homologous to a family of proteins that actively transport small solutes in an ATP dependent manner (ABC transporters). The regulator protein is a protein which is embedded in the cell membrane and acts as a channel for certain ions to be transported into or out of the cell. The disease cystic fibrosis is caused by a defect in the gene for this protein. (09 Oct 1997) |
| progressive massive fibrosis | <radiology> Progressive massive fibrosis, silicosis (properly conglomerate nodules, not progressive massive fibrosis), coal worker's pneumoconiosis, density (conglomerate mass) in upper lobe, retracts toward hilum, leaves emphysematous change (bullae) at lung periphery (12 Dec 1998) |
| scleroderma, systemic | A chronic, progressive dermatosis characterised by boardlike hardening and immobility of the affected skin, with visceral involvement, especially of lungs, oesophagus, kidneys and heart. It may be accompanied by calcinosis, raynaud's phenomenon, and telangiectasis (crest syndrome). It includes acrosclerosis and sclerodactyly. (12 Dec 1998) |
| pulmonary fibrosis | Chronic inflammation and progressive fibrosis of the pulmonary alveolar walls, with steadily progressive dyspnea, resulting finally in death from oxygen lack or right heart failure. (12 Dec 1998) |
| subadventitial fibrosis | Fibrosis in the outer media of arteries, usually the renal arteries of young women, where it causes segmental stenosis and hypertension; a variety of fibromuscular dysplasia. Synonym: subadventitial fibrosis. (05 Mar 2000) |
| nodular subepidermal fibrosis | A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries with scattered haemosiderin-pigmented and lipid macrophages. They are common, usually about 1 cm in diameter and occur in the dermis. Simple excision is always curative. (12 Dec 1998) |
| Symmers' fibrosis | A characteristic pipe-shaped fibrosis formed around hepatic portal veins in some cases of long-continued heavy infection with Schistosoma mansoni; thought to be induced by the presence of large numbers of schistosome eggs in the hepatic tissues. Synonym: Symmers' clay pipestem fibrosis, Symmers' fibrosis. (05 Mar 2000) |
| systemic | <anatomy> Pertaining to or affecting the body as a whole. (18 Nov 1997) |
| systemic anaphylaxis | The immediate response, involving smooth muscles and capillaries throughout the body of a sensitised individual, that follows intravenous (and occasionally intracutaneous) injection of antigen (allergen). See: anaphylactic shock. Synonym: systemic anaphylaxis. (05 Mar 2000) |
| systemic anatomy | Anatomy of the systems of the body; an approach to anatomical study organised by organ systems, e.g., the cardiovascular system, emphasizing an overview of the system throughout the body; distinguished from regional anatomy. (05 Mar 2000) |
| systemic autoimmune diseases | A group of connective tissue disease's characterised by the presence of autoantibodies responsible for immunopathologically mediated tissue lesions; systemic lupus erythematosus is the prototype. (05 Mar 2000) |
| systemic blastomycosis | Infection with Blastomyces dermatitidis extending beyond the skin or the lung, the usual portals of entry; involvement of bone and genitourinary tract (especially. Prostate and epididymis) are most frequent. (05 Mar 2000) |
| systemic chondromalacia | A degenerative disease of cartilage producing a bizarre form of arthritis, with collapse of the ears, the cartilaginous portion of the nose, and the tracheobronchial tree; death may occur from chronic infection or suffocation because of loss of stability in the tracheobronchial tree of autosomal origin. Synonym: chronic atrophic polychondritis, generalised chondromalacia, Meyenburg's disease, Meyenburg-Altherr-Uehlinger syndrome, relapsing perichondritis, systemic chondromalacia, von Meyenburg's disease. (05 Mar 2000) |
| systemic circulation | The circulation of blood through the arteries, capillaries, and veins of the general system, from the left ventricle to the right atrium. Synonym: greater circulation. (05 Mar 2000) |