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N-hydroxy-2-acetylaminofluorene reductase <enzyme> Dehydroxylates n-hydroxy-2-acetylaminofluorene to 2-acetylaminofluorene; can use cysteine, glutathione, dithiothreitol, 2-mercaptoeethanol, NADPH or NADH as electron donor
Registry number: EC 1.14.99.-
Synonym: n-hydroxy-aaf reductase
(26 Jun 1999)
N-hydroxy-2-acetylaminofluorene sulfotransferase <enzyme> From rat liver; forms non-mutagenic n-o-sulfo-2-acetylaminofluorene
Registry number: EC 2.8.2.-
Synonym: haf-sulfotransferase
(26 Jun 1999)
succinyl-CoA-3-hydroxy-3-methylglutarate CoA transferase <enzyme> Rat liver mitochondrial enzyme which catalyses transfer of a conezyme a molecule from succinyl-CoA to 3-hydroxy-3-methylglutarate
Registry number: EC 2.8.3.-
Synonym: succinylcoa-hmg CoA transferase, sca-hmg cat
(26 Jun 1999)
kanamycin - alpha-hydroxy-gamma-aminobutyl acylase <enzyme> Transforms kanamycin into amikacin
Registry number: EC 2.3.1.-
Synonym: alpha-hydroxy-gamma-aminobutyl acylase, haba acylase
(26 Jun 1999)
2,5-diamino-6-hydroxy-4-ribosylaminopyrimidine-5'-phosphate reductase <enzyme> Nadp-dependent; forms 2,5-diamino-6-hydroxy-4-ribitylaminopyrimidine-5'-phosphate; intermediate in riboflavin biosynthesis
Registry number: EC 1.1.1.-
Synonym: dahrampp reductase, 2,5-diamino-4-oxy-6-ribosylaminopyrimidine-5'-phosphate reductase
(26 Jun 1999)
2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase <enzyme> Catalyses conversion of 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate to 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate; enzyme d of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 4.1.1.-
Synonym: cmtd gene product
(26 Jun 1999)
2-hydroxy-3-oxoadipate synthase <enzyme> Deficient in hyperoxaluria type i
Registry number: EC 4.1.3.15
Synonym: 2-ketoglutarate-glyoxylate carboligase, glyoxylate-oxoglutarate carboligase, delta-hydroxylaevulinate synthase, 2-oxoglutarate-glyoxylate carboligase, 2-hydroxy-3-oxoadipate carboxylase
(26 Jun 1999)
2-hydroxy-3-oxopropionate reductase <enzyme> Catalyses reversibly the reduction of glycerate to 2-hydroxy-3-oxopropanate in the presence of nad(p+)
Registry number: EC 1.1.1.60
Synonym: tartronate saemialdehyde reductase, tsa reductase
(26 Jun 1999)
2-hydroxy-4-carboxymucconate-6-saemialdehyde dehydrogenase <enzyme> Catalyses alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde to alpha-hydroxy-gamma-carboxymuconic acid
Registry number: EC 1.2.1.45
Synonym: alpha-hydroxy-gamma-carboxymuconic-epsilon-saemialdehyde dehydrogenase, chms dehydrogenase
(26 Jun 1999)
2-hydroxy-5-nitrobenzyl bromide <chemical> 2-(bromomethyl)-5-nitrophenol. A chemical reagent that reacts with and modifies chemically the tryptophan portion of protein molecules. Used for 'active site' enzyme studies and other protein studies. Sometimes referred to as koshland's reagent.
Pharmacological action: indicators and reagents.
Chemical name: Phenol, 2-(bromomethyl)-4-nitro-
(12 Dec 1998)
2-hydroxy-6-oxo-2,4-heptadienoate hydrolase <enzyme> Above cpd hydrolyzed to 2-oxopent-4-enoate (2-hydroxypenta-2,4-dienoate); enzyme e of p-cumate catabolic pathway in pseudomonas putida
Registry number: EC 3.7.-
Synonym: hodh hydrolase, 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase, cmte gene product
(26 Jun 1999)
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase <enzyme> E coli enzyme; catalyses formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate from 2-ketoglutarate and isochorismate; requires thiamine pyrophosphate and liberates pyruvate from the isochorismate molecule; see also o-succinylbenzoate synthase
Registry number: EC 4.1.3.-
Synonym: shchc synthase
(26 Jun 1999)
3a-hydroxy-5a-pregnan-20-one A catabolite of progesterone; found in the urine of pregnant women.
(05 Mar 2000)
3 beta-hydroxy-delta 5-C(27)-steroid dehydrogenase <enzyme> Second enzyme in the sequence that converts cholesterol to bile acids; deficiency leads to chronic liver disease in childhood
Registry number: EC 1.1.1.-
Synonym: 7 alpha-hydroxycholesterol 3 beta-dehydrogenase, 7-hydroxycholesterol 3-dehydrogenase, 3 beta-hydroxy-delta(5)-c(27)-steroid oxidoreductase, 5-cholestene-3beta,7alpha-diol oxidase
(26 Jun 1999)
3-hydroxy-2-methylpropionyl-CoA dehydrogenase <enzyme> Forms methylmalonyl-CoA saemialdehyde
Registry number: EC 1.1.1.-
Synonym: 3-hydroxyisobutyryl-CoA dehydrogenase
(26 Jun 1999)
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