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Hunter's membrane The mucous membrane of the pregnant uterus that has already undergone certain changes, under the influence of the ovulation cycle, to fit it for the implantation and nutrition of the ovum; so-called because the membrane is cast off after labour.
Synonym: membrana decidua, caduca, decidua, Hunter's membrane.
(05 Mar 2000)
Hunter's operation Ligation of the artery proximal and distal to an aneurysm.
(05 Mar 2000)
Hunter's syndrome <syndrome> An error of mucopolysaccharide metabolism characterised by deficiency of iduronate sulfatase, with excretion of dermatan sulfate and heparan sulfate in the urine; clinically similar to Hurler's syndrome but distinguished by less severe skeletal changes, no corneal clouding, and X-linked recessive inheritance.
Synonym: type II mucopolysaccharidosis.
(05 Mar 2000)
Hunter, Charles <person> Canadian physician, 1872-1955.
See: Hunter's syndrome.
(05 Mar 2000)
Hunter, John <person> Scottish surgeon, anatomist, physiologist and pathologist, 1728-1793.
See: Hunter's canal, Hunter's gubernaculum, Hunter's operation, Hunter-Schreger bands, Hunter-Schreger lines.
(05 Mar 2000)
Hunter, William <person> Scottish anatomist and obstetrician, 1718-1783.
See: Hunter's ligament, Hunter's line, Hunter's membrane.
(05 Mar 2000)
Hunter, William A <person> English pathologist, 1861-1937.
See: Hunter's glossitis.
(05 Mar 2000)
Hunter-Schreger bands Alternating light and dark lines seen in dental enamel that begin at the dentoenamel junction and end before they reach the enamel surface; they represent areas of enamel rods cut in cross-sections dispersed between areas of rods cut longitudinally.
Synonym: Hunter-Schreger lines, Schreger's lines.
(05 Mar 2000)
Hunter-Schreger lines Alternating light and dark lines seen in dental enamel that begin at the dentoenamel junction and end before they reach the enamel surface; they represent areas of enamel rods cut in cross-sections dispersed between areas of rods cut longitudinally.
Synonym: Hunter-Schreger lines, Schreger's lines.
(05 Mar 2000)
hunting The pursuit of game or of wild animals. Happy hunting grounds, the region to which, according to the belief of American Indians, the souls of warriors and hunters pass after death, to be happy in hunting and feasting. Hunting box. Same As Hunting lodge (below).
<medicine> Hunting cat, a spider which hunts its prey, instead of catching it in a web; a wolf spider. Hunting watch. See Hunter.
Source: Websters Dictionary
(01 Mar 1998)
hunting phenomenon An unusual reaction of digital blood vessels exposed to cold; vasoconstriction is alternated with vasodilation in irregular repeated sequences, in an apparent hunting of equilibrium of skin temperature.
Synonym: hunting phenomenon.
(05 Mar 2000)
hunting reaction An unusual reaction of digital blood vessels exposed to cold; vasoconstriction is alternated with vasodilation in irregular repeated sequences, in an apparent hunting of equilibrium of skin temperature.
Synonym: hunting phenomenon.
(05 Mar 2000)
huntingtin <molecular biology> Protein product of the IT15 gene that has variable numbers of polyglutamine repeats in Huntingdon's disease. The IT15 gene is widely expressed and required for nomal development. The polyglutamine repeats (44 in the commonest form of the disease) increase the interaction of huntingtin with huntingtin associated protein 1 (HAP 1) which is enriched in the brain and may be associated with pathology. Nature, 378: 398
(18 Nov 1997)
Huntington George, U.S. Physician, 1850-1916.
See: Huntington's chorea, Huntington's disease.
(05 Mar 2000)
Huntington chorea <neurology> An inherited adult-onset disease of the central nervous system.
It is characterised by dementia and bizarre involuntary movements. The disease is progressive and there is currently no known cure.
The identification of the gene (huntingtin) on chromosome 4p now allows for direct mutation analysis. The gene contains a trinucleotide repeat (CAG) that is found to be expanded in length in affected patients. The normal allele size ranges from 11 to 34 triplet repeat units, while 42 repeats or greater is considered diagnostic of Huntington disease.
As in other trinucleotide repeat disorders, the phenomenom of anticipation has been observed, in this case expressed as earlier age of onset in offspring, particularly with paternal transmission. A further complication is the presence of two neighboring trinucleotide repeats (both CCG) which can expand independently without causing the disease.
Early PCR primer sets encompassed these adjacent repeats, potentially yielding false positive test results, newer primers hone in more closely on the CAG repeat sequence.
Careful attention must be paid to the psychosocial support structure of prospective test subjects in Huntington disease genetic counseling. Established protocols require systematic neuropsychiatric assessment and informed consent prior to DNA testing.
Inheritance: autosomal dominant.
(29 Dec 1997)
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