| congenital severe combined immunodeficiency | Disease, one form of which is caused by the lack of a transcription factor required for expression of HLA class II genes. (18 Nov 1997) |
|---|---|
| murine acquired immunodeficiency syndrome | <syndrome> Acquired defect of cellular immunity that occurs in mice infected with mouse leukaemia viruses (mulv). The syndrome shows striking similarities with human aids and is characterised by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas. (12 Dec 1998) |
| secondary immunodeficiency | Immunodeficiency in which there is no evident defect in the lymphoid tissues, but rather hypercatabolism or loss of immunoglobulins such as occurs in familial idiopathic hypercatabolic hypoproteinaemia or in defects associated with the nephrotic syndrome. Synonym: secondary agammaglobulinaemia, secondary antibody deficiency, secondary hypogammaglobulinaemia. (05 Mar 2000) |
| severe combined immunodeficiency | Group of rare congenital disorders characterised by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an x-linked or autosomal recessive defect. About half of the patients with autosomal recessive scid are deficient in the enzyme adenosine deaminase. (12 Dec 1998) |
| simian acquired immunodeficiency syndrome | <syndrome> Acquired defect of cellular immunity that occurs naturally in macaques infected with srv serotypes, experimentally in monkeys inoculated with srv or mason-pfiser monkey virus (mpmv), or in monkeys infected with siv. (12 Dec 1998) |
| immunodeficiency | Inabillity to mount a normal immune response. Immunodeficiency can be due to a genetic disease or acquired as in aids due to HIV. (12 Dec 1998) |
| immunodeficiency disorders | <radiology> B-cell (antibody) deficiency: high-grade pathogens: pneumococcus, strep, H. Flu, chronic sinopulmonary disease, usual survival to adulthood, T-cell (cellular) deficiency: low-grade pathogens: fungi, viruses, Pneumocystic, growth retardation, diarrhoea, delayed anergy, short life-span, susceptible to graft vs. Host (GvH) disease, e.g.: DiGeorge syndrome, Nezelhof syndrome Note: increased risk of malignancy (12 Dec 1998) |
| immunodeficiency syndrome | <syndrome> An immunological deficiency or disorder, of which the chief symptom is an increased susceptibility to infection, the pattern of susceptibility being dependent upon the kind of deficiency. See: immunodeficiency. (05 Mar 2000) |
| immunodeficiency with elevated IgM | Immunodeficiency with reduced IgG and IgA-bearing cells; there is recurrent pyogenic infection; X-linked in some families. (05 Mar 2000) |
| immunodeficiency with hypoparathyroidism | diGeorge syndrome |
| feline acquired immunodeficiency syndrome | <syndrome> Acquired defect of cellular immunity that occurs in cats infected with feline immunodeficiency virus (fiv) and in some cats infected with feline leukaemia virus (felv). (12 Dec 1998) |
| bovine virus diarrhoea virus | A virus of the genus Pestivirus, in the family Togaviridae, causing bovine virus diarrhoea; New York, Oregon, and Indiana strains of the virus are recognised. Synonym: mucosal disease virus. (05 Mar 2000) |
| abelson leukaemia virus | A defective murine leukaemia virus capable of transforming lymphoid cells and producing a rapidly progressing lymphoid leukaemia after superinfection with friend, moloney, or rauscher virus. (12 Dec 1998) |
| Abelson murine leukaemia virus | A retrovirus belonging to the Type C retrovirus group subfamily (family Oncovirinae) which is associated with leukaemia and produces in vitro transformation of mouse cells. (05 Mar 2000) |
| adeno-associated virus | <virology> A genus of viruses in the family Parvoviridae which are all defective viruses (unable to replicate by themselves) and depend on the co-infection of their host cell by other, nondefective viruses to help them replicate. (09 Oct 1997) |