| LAI | latex particle agglutination inhibition; leukocyte adherence inhibition |
|---|---|
| LAI assay | Leukocyte Adherence Inhibition assay |
| MIF | 1) Mllerian Inhibiting Factor 2) Migrating Inhibition Factor |
| TBII | TSH Binding Inhibiting(= Inhibition) Immunoglobulin |
| AGPI | agar gel precipitin inhibition |
| reciprocal inhibition | Contraction in a muscle is accompanied by a loss of tone or by relaxation in the antagonistic muscle. Synonym: reciprocal inhibition. (05 Mar 2000) |
|---|---|
| reflex inhibition | A situation in which sensory stimuli decrease reflex activity. (05 Mar 2000) |
| cell migration inhibition | Phenomenon of cell-mediated immunity measured by in vitro inhibition of the migration or phagocytosis of antigen-stimulated leukocytes or macrophages. Specific assays have been developed to estimate levels of migration-inhibitory factor, immune reactivity against tumour-associated antigens, and immunosuppressive effects of infectious microorganisms. (12 Dec 1998) |
| central inhibition | <physiology> Suppression or diminution of outgoing impulses from a reflex centre. (05 Mar 2000) |
| residual inhibition | The inhibition or suppression of tinnitus by use of a sound-generating device (residual inhibitor) which masks the sounds of tinnitus and produces a residual sound-inhibiting effect when the device is turned off. (05 Mar 2000) |
| retroactive inhibition | The partial or complete obliteration of memory by a more recent event, particularly new learning. Compare: proactive inhibition. (05 Mar 2000) |
| migration inhibition test | A test which measures the presence of migration-inhibitory factor. Usually peritoneal macrophages are placed in a capillary tube in the presence or absence of supernatants from activated T-cells. If MIF is present, the migration of monocyte/macrophages is reduced. Synonym: macrophage migration inhibition test, migration inhibition test. (05 Mar 2000) |
| Wedensky inhibition | Inhibition of muscle response resulting from application of a series of rapidly repeated stimuli to the motor nerve where slower frequency of stimulation results in muscle response. (05 Mar 2000) |
| competitive inhibition | <chemistry> Inhibitor that occupies the active site of an enzyme or the binding site of a receptor and prevents the normal substrate or ligand from binding. at sufficiently high concentration of the normal ligand inhibition is lost: the Km is altered by the competitive inhibitor, but the Vmax remains the same. (05 Jan 1998) |
| contact inhibition | The inhibition of continued growth and division of a cell or colony due to physical contact with other cells or colonies. The stopping of continued growth when a certain density of cells has been reached. The momentary stopping of all movement when a mobile cell runs into another cell. (09 Oct 1997) |
| contact inhibition of growth | See: density dependent inhibition. (18 Nov 1997) |
| contact inhibition of movement | Reaction in which the direction of motion of a cell is altered following collision with another cell. In heterologous contacts both cell may respond (mutual inhibition) or only one (nonreciprocal). Type I contact inhibition involves paralysis of the locomotory machinery, Type II is a consequence of adhesive preference for the substratum rather than the dorsal surface of the other cell. (18 Nov 1997) |
| contact inhibition of phagocytosis | Phenomenon described in sheets of kidney epithelial cells that, when confluent, lose their weak phagocytic activity, probably because of a failure of adhesion of particles to the dorsal surface in the absence of ruffles. (18 Nov 1997) |
| potassium inhibition | Arrest of the heart in the fully relaxed state as a result of potassium intoxication. (05 Mar 2000) |
| haptenic inhibition | <immunology, molecular biology> Could be considered an isolated epitope: although a hapten (by definition) has an antibody directed against it, the hapten alone will not induce an immune response if injected into an animal, it must be conjugated to a carrier (usually a protein). The hapten constitutes a single antigenic determinant, perhaps the best known example is dinitro phenol (DNP) that can be conjugated to BSA and against which antiDNP antibodies are produced (antibodies to the BSA can be adsorbed out). Because the hapten is monovalent, immune complex formation will be blocked if the soluble hapten is present as well as the hapten carrier conjugate (assuming there is more than one hapten per carrier then an immune precipitate can be formed). Competitive inhibition by the soluble small molecule is sometimes referred to as haptenic inhibition and this term has carried over into lectin mediated haemagglutination where monosaccharides are added to try to block haemagglutination: the blocking sugar defines the specificity of the lectin. (18 Nov 1997) |