| MAN-6-P | mannose-6-phosphate |
|---|---|
| MBP | major basic protein; maltose-binding protein; management by policy; mannose-binding protein; mean bl... |
| MPI | mannose phosphate isomerase; master patient index; maximum permitted intake; maximum point of impuls... |
| MPR | mannose 6-phosphate receptor; marrow production rate; massive preretinal retraction; maximum pulse r... |
| MPRD | cation-dependent mannose 6-phosphate receptor |
| mannose-6-phosphate | <biochemistry> Mannose derivative formed by phosphorylation in the Golgi complex of certain mannose residues on N glycan chains of lysosomal enzymes. Believed to function as targetting signal that causes entry of these enzymes to the lysosomes. The receptor (215 kD) is enriched in specialised pre lysosomes. (18 Nov 1997) |
|---|---|
| mannose-6-phosphate isomerase | <enzyme> An enzyme that catalyses the reversible isomerization of d-mannose-6-phosphate to form d-fructose-6-phosphate, an important step in glycolysis. Chemical name: D-Mannose-6-phosphate ketol isomerase Registry number: EC 5.3.1.8 (12 Dec 1998) |
| mannose-6-phosphate receptors | Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) |
| mannose-6-phosphate reductase | <enzyme> Involved in biosynthesis of mannitol in celery Registry number: EC 1.1.1.224 Synonym: manp reductase (26 Jun 1999) |
| phosphoenolpyruvate-mannose phosphotransferase | <enzyme> Consists of three subunits IIab(man), IIc(man), and IId(man); many encodes IIc(man) and manz encodes IId(man) Registry number: EC 2.7.1.- Synonym: enzyme II (mannose), mannose permease, many gene product, manz gene product, IIab(man) subunit, IIc(man) subunit, IId(man) subunit (26 Jun 1999) |
| high mannose oligosaccharide | <biochemistry> A subset of the N glycan chains that are added post translationally to certain asparagine residues of secreted or membrane proteins in eukaryotic cells, contain 5-9 mannose residues, but lack the sialic acid terminated antennae of the so called complex type. (18 Nov 1997) |
| D mannose | <chemical> Hexose identical to D glucose except that the orientation of the H and OH on carbon 2 are interchanged (i.e. The 2 epimer of glucose). Found as constituent of polysaccharides and glycoproteins. (18 Nov 1997) |
| dolichol monophosphate mannose | <chemical> A lipophilic glycosyl carrier of the monosaccharide mannose in the biosynthesis of oligosaccharide phospholipids and glycoproteins. Chemical name: beta-D-Mannopyranose, 1-ester with dolichol dihydrogen phosphate (12 Dec 1998) |
| dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase | <enzyme> Catalyses the transfer of mannose from dolichyl-p-mannose to the man(5)(glcnac)2-pp-dolichol acceptor glycolipid Registry number: EC 2.4.1.130 Synonym: dolichyl-p-mannose-dolichyl-pp-heptasaccharide alpha-mannosyltransferase, dolichyl-p-mannose-man(5)(glcnac)2-pp-dolichol mannosyltransferase, dpm-g-mannosyltransferase (26 Jun 1999) |
| dolichyl-phosphate-mannose phosphodiesterase | <enzyme> Chicken liver microsome enzyme releases mannose plus dolichyl phosphate Registry number: EC 3.1.4.49 Synonym: dol-p-man phosphodiesterase, mannosylphosphodolichol phosphodiesterase (26 Jun 1999) |
| dolichyl-phosphate-mannose - protein mannosyltransferase | <enzyme> Dol-p-man is mannosyl donor to oh group of threonine or serine residues in proteins in fungi Registry number: EC 2.4.1.109 Synonym: protein o-mannosyltransferase, dol-p-man - protein o-d-mannosyltransferase, pmt1 protein, pmt2 protein, pmt3 protein, pmt4 protein (26 Jun 1999) |
| guanosine | <biochemistry, molecular biology> The nucleoside formed by linking ribose to guanine. (18 Nov 1997) |
| guanosine 5'-monophosphate | A major component of ribonucleic acids. Synonym: guanine ribonucleotide, guanosine 5'-monophosphate. Guanylic acid reductase (GMP reductase), an enzyme that catalyses the reaction of GMP with NADPH producing IMP, NH3, and NADP+; a part of the purine salvage pathway. Guanylic acid synthetase (GMP synthetase), an enzyme catalyzing the reaction of l-glutamine, XMP, and ATP to produce GMP, l-glutamate, AMP, and pyrophosphate; a key step in purine biosynthesis. Acronym: GMP (05 Mar 2000) |
| guanosine 5'-o-(3-thiotriphosphate) | <chemical> Guanosine 5'-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid. A stable GTP analog which enjoys a variety of physiological actions such as stimulation of guanine nucleotide-binding proteins, phosphoinositide hydrolysis, cyclic AMP accumulation, and activation of specific proto-oncogenes. Chemical name: Guanosine 5'-(trihydrogen diphosphate), P'-anhydride with phosphorothioic acid (12 Dec 1998) |
| guanosine 5'-triphosphate | An immediate precursor of guanine nucleotides in RNA; similar to ATP; has a crucial role in microtubule formation. GTP cyclohydrolase, an enzyme that catalyses the reaction of GTP and H2O forming formate and a precursor of tetrahydrobiopterin; a deficiency of this enzyme will result in one form of malignant hyperphenylalaninaemia. Acronym: GTP (05 Mar 2000) |