| CGI | chronic granulomatous inflammation; Clinical Global Impression [scale]; common gateway interface [of... |
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| FGD | fatal granulomatous disease |
| GANS | granulomatous angiitis of the nervous system |
| GBD | gallbladder disease; gender behavior disorder; glass blower's disease; granulomatous bowel disease |
| GC | ganglion cell; gas chromatography; general circulation; general closure; general condition; generali... |
| chronic granulomatous disease | <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase. Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the cells are tested. The absence of the oxygen dependent killing mechanism is not itself fatal but seriously compromises the primary defense system. at least three separate lesions can cause the syndrome, the commonest being a defect in plasma membrane cytochrome. Acronym: CGD (12 Jan 1998) |
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| chronic granulomatous disease of childhood | <radiology> Disorder of phagocytosis, two forms: X-linked recessive, autosomal recessive, usually fatal in childhood, infection by nonpathogenic organisms (catalase positive), pneumonia, osteomyelitis, diarrhoea, abdominal pain Findings: recurrent pneumonia (resolves incompletely, with abscess formation), adenopathy (big hila), hepatosplenomegaly, calcified granulomata in liver, spleen, lymph nodes, gastric antral narrowing (!) Cf: Chediak-Higashi syndrome More info: chronic granulomatous disease (12 Dec 1998) |
| neurocranial granulomatous arteritis | A small vessel giant cell arteritis which affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a lower grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| subacute granulomatous thyroiditis | Thyroiditis with round cell (usually lymphocytes) infiltration, destruction of thyroid cells, epithelial giant cell proliferation, and evidence of regeneration; thought by some to be a reflection of a systemic infection and not an example of true chronic thyroiditis. Synonym: de Quervain's thyroiditis, giant cell thyroiditis. (05 Mar 2000) |
| intracranial granulomatous arteritis | A small vessel, giant cell arteritis that affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a low grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| enteritis, granulomatous | Crohn's disease by another name, a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease usually affects persons in their teens or early twenties. It tends to be a chronic, recurrent condition with periods of remission and exacerbation. In the early stages, Crohn's disease causes small scattered shallow crater-like areas (erosions) called apthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causinG scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs.When only the large intestine (colon) is involved, the condition is called Crohn's colitis. When only the small intestine is involved, the condition is called Crohn's enteritis. When only the end of the small intestine (the terminal ileum) is involved, it is termed terminal ileitis. When both the small intestine and the large intestine are involved, the condition is called Crohn's enterocolitis (or ileocolitis). Abdominal pain, diarrhoea, vomiting, fever, and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium X-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery. (The disease is also called regional enteritis). (12 Dec 1998) |
| acute disseminated encephalomyelitis | <radiology> Immune-mediated encephalitis (IME), ADE, allergic treatmentn to prior infection, begins 1-2 weeks after event, occus after viral infection or vaccination, affects corpus callosum and white matter (above and below tent), self-limited; steroids may help See also: white-matter disease, demyelinating disease (12 Dec 1998) |
| acute necrotizing haemorrhagic encephalomyelitis | A fulminating demyelinating disorder of the central nervous system that affects mainly children and young adults. Almost always preceded by a respiratory infection, characterised by the abrupt onset of fever, headache, confusion, and nuchal rigidity, soon followed by focal seizures, hemiplegia, or quadriplegia, brainstem findings, and coma; the CSF shows evidence of an inflammatory process; due to the massive destruction of the white matter of one or both hemispheres, often accompanied by similar destruction of the white matter of the brainstem and cerebellar peduncles; of unknown aetiology. Synonym: acute haemorrhagic leukoencephalitis, acute necrotizing haemorrhagic leukoencephalitis. (05 Mar 2000) |
| avian encephalomyelitis virus | <virology> A virus of the genus Enterovirus (family Picornaviridae) causing avian infectious encephalomyelitis in young chicks. (05 Mar 2000) |
| avian infectious encephalomyelitis | <veterinary> A disease of very young chicks caused by a picornavirus and characterised by tremor, ataxia, somnolence, and finally death. Synonym: epidemic tremor. (05 Mar 2000) |
| benign myalgic encephalomyelitis | An epidemic disease characterised by stiffness of the neck and back, headache, diarrhoea, fever, and localised muscular weakness; restricted almost exclusively to adults, affecting women more than men; probably viral in origin. Synonym: Akureyri disease, benign myalgic encephalomyelitis, epidemic myalgic encephalomyelitis, Iceland disease. (05 Mar 2000) |
| bovine sporadic encephalomyelitis | An acute, septic encephalomyelitis, pleuritis, and peritonitis of cattle caused by Chlamydia psittaci; it occurs in the north central United States. Synonym: Buss disease. (05 Mar 2000) |
| caprine arthritis-encephalomyelitis | A worldwide disease of goats caused by the caprine arthritis-encephalomyelitis virus; two syndromes are recognised, encephalomyelitis in kids and more commonly arthritis in adults. (05 Mar 2000) |
| caprine arthritis-encephalomyelitis virus | A lentivirus causing caprine arthritis-encephalomyelitis in goats. (05 Mar 2000) |
| Venezuelan equine encephalomyelitis | A form of mosquito-borne equine encephalomyelitis found in parts of South America, Panama, and Trinidad, caused by the Venezuelan equine encephalomyelitis virus (a species of Alphavirus in the family Togaviridae), and characterised by less central nervous system involvement than occurs in either eastern or western equine encephalomyelitis; fever, diarrhoea, and depression are common; in man, there is fever and severe headache after an incubation period of 2 to 5 days, and in a few cases there has been central nervous system involvement. (05 Mar 2000) |