| FGD | fatal granulomatous disease |
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| GANS | granulomatous angiitis of the nervous system |
| GBD | gallbladder disease; gender behavior disorder; glass blower's disease; granulomatous bowel disease |
| GC | ganglion cell; gas chromatography; general circulation; general closure; general condition; generali... |
| GHR | granulomatous hypersensitivity reaction |
| granulomatous rosacea | Papular lesions in rosacea, characterised microscopically by perifollicular granulomas with central necrosis and scattered giant cells. Lupus miliaris disseminatus faciei is probably a form of granulomatous rosacea. Synonym: rosacea-like tuberculid, tuberculoid rosacea. (05 Mar 2000) |
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| chronic granulomatous disease | <disease> Chronic granulomatous disease is usually fatal in childhood, in which the production of hydrogen peroxide by phagocytes does not occur because of a lesion in an NADP dependent oxidase. Catalase negative bacteria are not killed and there is no luminol enhanced chemiluminescence when the cells are tested. The absence of the oxygen dependent killing mechanism is not itself fatal but seriously compromises the primary defense system. at least three separate lesions can cause the syndrome, the commonest being a defect in plasma membrane cytochrome. Acronym: CGD (12 Jan 1998) |
| chronic granulomatous disease of childhood | <radiology> Disorder of phagocytosis, two forms: X-linked recessive, autosomal recessive, usually fatal in childhood, infection by nonpathogenic organisms (catalase positive), pneumonia, osteomyelitis, diarrhoea, abdominal pain Findings: recurrent pneumonia (resolves incompletely, with abscess formation), adenopathy (big hila), hepatosplenomegaly, calcified granulomata in liver, spleen, lymph nodes, gastric antral narrowing (!) Cf: Chediak-Higashi syndrome More info: chronic granulomatous disease (12 Dec 1998) |
| neurocranial granulomatous arteritis | A small vessel giant cell arteritis which affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a lower grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| subacute granulomatous thyroiditis | Thyroiditis with round cell (usually lymphocytes) infiltration, destruction of thyroid cells, epithelial giant cell proliferation, and evidence of regeneration; thought by some to be a reflection of a systemic infection and not an example of true chronic thyroiditis. Synonym: de Quervain's thyroiditis, giant cell thyroiditis. (05 Mar 2000) |
| intracranial granulomatous arteritis | A small vessel, giant cell arteritis that affects only intracranial blood vessels, of unknown aetiology, and with diverse clinical manifestations, including those seen with an involving cerebral tumour, and with a low grade meningitis, leading to infarction of one portion of the cerebrum or cerebellum. (05 Mar 2000) |
| enteritis, granulomatous | Crohn's disease by another name, a chronic inflammatory disease of the intestine primarily in the small and large intestines but which can occur anywhere in the digestive system between the mouth and the anus. Named after Burrill Crohn who described the disease in 1932. The disease usually affects persons in their teens or early twenties. It tends to be a chronic, recurrent condition with periods of remission and exacerbation. In the early stages, Crohn's disease causes small scattered shallow crater-like areas (erosions) called apthous ulcers in the inner surface of the bowel. With time, deeper and larger ulcers develop, causinG scarring and stiffness of the bowel and the bowel becomes increasingly narrowed, leading to obstruction. Deep ulcers can puncture holes in the bowel wall, leading to infection in the abdominal cavity (peritonitis) and in adjacent organs.When only the large intestine (colon) is involved, the condition is called Crohn's colitis. When only the small intestine is involved, the condition is called Crohn's enteritis. When only the end of the small intestine (the terminal ileum) is involved, it is termed terminal ileitis. When both the small intestine and the large intestine are involved, the condition is called Crohn's enterocolitis (or ileocolitis). Abdominal pain, diarrhoea, vomiting, fever, and weight loss can be symptoms. Crohn's disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is by barium enema, barium X-ray of the small bowel, and colonoscopy. Treatment includes medications for inflammation, immune suppression, antibiotics, or surgery. (The disease is also called regional enteritis). (12 Dec 1998) |