| EGM | electrogram; extracellular granular material |
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| GC | ganglion cell; gas chromatography; general circulation; general closure; general condition; generali... |
| GER | gastroesophageal reflux; geriatrics; granular endoplasmic reticulum |
| GPC | gastric parietal cell; gel permeation chromatography; giant papillary conjunctivitis; glycophorin C;... |
| LGL-NK | large granular lymphocyte-natural killer |
| ophthalmia, sympathetic | Granulomatous uveitis which follows in one eye after a penetrating injury to the other eye; the secondarily affected eye is called the sympathizing eye, and the injured eye is called the exciting or activating eye. (12 Dec 1998) |
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| Egyptian ophthalmia | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| transferred ophthalmia | A serous or plastic uveitis caused by a perforating wound of the uvea followed by a similar severe reaction in the other eye that may lead to bilateral blindness. Synonym: transferred ophthalmia. (05 Mar 2000) |
| endophthalmitis ophthalmia nodosa | Endophthalmitis due to intraocular caterpillar hairs. See: ophthalmia nodosa. (05 Mar 2000) |
| Paneth's granular cells | Cell's, located at the base of intestinal glands of the small intestine, which contain large acidophilic refractile granules and may produce lysozyme. Synonym: Davidoff's cells. (05 Mar 2000) |
| granular | 1. Composed of or resembling granules or granulations. 2. Particles with strong affinity for nuclear stains, seen in many bacterial species. (05 Mar 2000) |
| granular cast | A relatively dark, dense urinary cast of coarsely or finely particulate cellular debris and other proteinaceous material, frequently seen in chronic renal disease but also in the recovery phase of acute renal failure. See: waxy cast. (05 Mar 2000) |
| granular cell tumour | Unusual tumour affecting any site of the body, but most often encountered in the head and neck. Considerable debate has surrounded the histogenesis of this neoplasm; however, it is considered to be a myoblastoma of, usually, a benign nature. It affects women more often than men. When it develops beneath the epidermis or mucous membrane, it can lead to proliferation of the squamous cells and mimic squamous cell carcinoma. (12 Dec 1998) |
| granular component of nucleolus | Area of nucleolus that appears granular in the electron microscope and contains 15nm diameter particles that are maturing ribosomes. In contrast to the pale staining and fibrillar areas. (18 Nov 1997) |
| granular conjunctivitis | A chronic infection of the conjunctiva due to Chlamydia trachomatis, characterised by conjunctival follicles and subsequent cicatrization. See: trachoma. Synonym: granular conjunctivitis. (05 Mar 2000) |
| granular cortex | See: cerebral cortex. (05 Mar 2000) |
| granular degeneration | Swelling of cells due to injury to the membranes affecting ionic transfer; causes an accumulation of intracellular water. Synonym: albuminous swelling, granular degeneration, hydropic degeneration, parenchymatous degeneration. (05 Mar 2000) |
| granular endoplasmic reticulum | Endoplasmic reticulum in which ribosomal granules are applied to the cytoplasmic surface of the cisternae; involved in the synthesis and secretion of protein via membrane-bound vesicles to the extracellular space. Synonym: chromidial substance, ergastoplasm, rough-surfaced endoplasmic reticulum. (05 Mar 2000) |
| granular kidney | A kidney in which fairly uniform, diffusely and evenly situated foci of scarring of the interstitial tissue of the cortex (and sometimes scarring of glomeruli), and the associated slight degree of bulging of groups of dilated tubules, leads to the development of a minutely bosselated surface; such kidney's are seen in arteriolar nephrosclerosis or chronic glomerulonephritis. Synonym: sclerotic kidney. (05 Mar 2000) |
| granular layer of a vesicular ovarian follicle | The layer of small cells that forms the wall of an ovarian follicle. Synonym: granular layer of a vesicular ovarian follicle, granulosa, membrana granulosa, stratum granulosum ovarii. (05 Mar 2000) |