| granular leukoblast | An obsolete term for promyelocyte. (05 Mar 2000) |
|---|---|
| granular leukocyte | Any one of the polymorphonuclear leukocyte's, especially a neutrophilic leukocyte. See: granulocyte, basophilic leukocyte, eosinophilic leukocyte. (05 Mar 2000) |
| granular lids | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| granular ophthalmia | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| granular pits | Pits on the inner surface of the skull, along the course of the superior sagittal sinus, in which are lodged the arachnoidal granulations. Synonym: foveolae granulares, pacchionian depressions. (05 Mar 2000) |
| granular pneumonocytes | Cuboidal cell's connected with the squamous pulmonary alveolar cell's and having in their cytoplasm lamellated bodies (cytosomes) that represent the source of the surfactant that coats the alveoli. Synonym: granular pneumonocytes, type II cells. (05 Mar 2000) |
| granular trachoma | <ophthalmology> The ordinary form of trachoma marked by the presence of granulations on the conjunctiva. Synonym: granular trachoma. (05 Mar 2000) |
| granular urethritis | <urology> Chronic urethritis with nodular lymphocytic infiltrations in the mucosa. Synonym: granular urethritis. (05 Mar 2000) |
| granular vaginitis | A condition of cattle manifested by the appearance of small, spherical, transparent nodules in the mucosa of the vagina of cows and of the penis of bulls; the mucosa is reddened and a mucopurulent exudate appears on the affected surfaces; it is a non specific hyperplastic response of the lymphatic tissue of these areas to an irritant or an antigen. (05 Mar 2000) |
| Tomes' granular layer | <dentistry> A thin layer of dentin adjacent to the cementum, appearing granular in ground sections; the granules are small uncalcified spaces. (05 Mar 2000) |
| acute kidney failure | <nephrology> A sudden decline in renal function may be triggered by a number of acute disease processes. Examples include sepsis (infection), shock, trauma, kidney stones, kidney infection, drug toxicity (aspirin or lithium), poisons or toxins (drug abuse) or after injection with an iodinated contrast dye (adverse effect). Chronic renal failure represents a slow decline in kidney function over time. Chronic renal failure may be caused by a number of disorders which include long-standing hypertension, diabetes, congestive heart failure, lupus or sickle cell anaemia. Both forms of renal failure result in a life-threatening metabolic derangement. (27 Sep 1997) |
| acute kidney transplant rejection | <radiology> Findings on ultrasound: globular enlargment of the kidney, swelling and hypoechogenicity of the medullary pyramids, indistinct cortico-medullary junction, foci in the renal cortex (12 Dec 1998) |
| african green monkey kidney cell | <cell culture> Cells taken from the kidneys of the African green monkey Cercopithecus aethiops sabaeus and used to grow certain viruses like poliovirus. (05 Feb 1998) |
| amyloid kidney | A kidney in which amyloidosis has occurred, usually in association with some chronic illness such as multiple myeloma, tuberculosis, osteomyelitis, or other chronic suppurative inflammation; such kidney's are moderately enlarged and grossly manifest a waxy appearance, with amyloid deposited beneath the endothelium in the glomerular loops and in the arterioles, apparently beginning as foci of thickening of the basement membranes. Synonym: waxy kidney. (05 Mar 2000) |
| anterior inferior segmental artery of kidney | Origin, anterior branch of renal. See: segmental arteries of kidney. Synonym: arteria segmenti anterioris inferioris renis, artery of anterior {inferior segment of kidney}. (05 Mar 2000) |