| 영문 | malignant tumor | 한글 | 악성종양 |
|---|---|---|---|
| 설명 | 정상적인 조직 세포가 각종 물리적-화학적-생물학적인 발암 물질의 작용 또는 요인에 의해 돌연변이를 일으켜서 형성되는 종양. 무제한의 세포분열로 매우 왕성하게 증식하여 주위조직을 파괴-침식한다. 또 어떤 화학물질을 내어 주위의 조직세포를 침해할 뿐만 아니라, 혈관 및 림프관을 따라 전이하여 전신의 카켁시아를일으켜 죽음을 초래한다. 상피성인 것을 암종이라 하고, 비상피성인 것을 육종이라 한다. |
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| 영문 | benign tumor | 한글 | 양성종양 |
|---|---|---|---|
| 설명 | 발육속도가 완만하여 성장에 한계가 있고, 주위와의 경계가 명확하며, 다른 조직으로 퍼지지 않으며, 침윤이나 전이를 일으키지 아니하는 종양. 섬유종이나 지방종 따위가 전형적인 예이다. 양성종양은 종양이 존재한다고 해도 1차적으로 숙주의 생명을 위협하는 일은 없다. 양성종양의 발육형식은 주위의 조직간에 왕래하는 일이 없이 주위의 조직을 밀어내며 증식한다. 발육속도는 완만하며 전이하거나 절제 후 재발하는 일이 극히 드물다. 종양성분은 변이체이긴 하지만 성숙한 정상세포와 거의 다른 것이 없다. 전신에 대한 영향은 악성종양의 경우 어느 정도 발육했을 때 전신의 영양상태가 손상되어 카켁시아가 되지만 양성종양의 경우 이런 일은 거의 없다. 양성종양과 악성종양의 성상의 차이에 엄밀한 경계는 없고, 경계경변으로 보이는 종양도 있다. |
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| 영문 | Wilms' tumor | 한글 | 윌름즈종양 |
|---|---|---|---|
| 설명 | 콩팥에서 발생하는 악성종양으로 소아에서 자주 발생한다. 흔히 소아에서 복부내종양을 발견시 중앙선을 넘어서면 신경모세포종이고, 중앙선을 넘지 않으면 윌름즈종양을 의심할 만큼 중요하고 흔한 종양이다. 대개 증상은 없는 편이며, 주로 아기의 목욕을 시켜주다가 우연히 발견된 복부내종괴 때문에 병원을 찾게 된다. 진단시 컴퓨터단층촬영으로 주위의 전이가 없는지를 확인해야 하며, 전이가 없으면 항암화학요법, 방사선치료요법, 그리고 수술요법의 병합요법에 의한 치료효과가 높다. |
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| 영문 | mucinous tumor | 한글 | 점액종양 |
|---|---|---|---|
| 설명 | 점액으로 구성된 종양을 말하는데 주로 여성의 난소에서 발생하는 낭성(물주머니같은 종양을 말함) 종양에서 많이 볼 수 있다. |
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| 영문 | tumor | 한글 | 종양 |
|---|---|---|---|
| 설명 | 조절할 수 없이 계속 진행되는 세포분열에 의한 조직의 새로운 증식 및 증대. 신생물. (1) 분류 A. 침윤과 전이의 유무에 따라 i)양성종양: 침윤과 전이가 없고 역형성이 낮은 세포로 구성됨. 대개 치료에 반응이 높고, 생명에 크게 지장이 없으며, 재발하는 경우도 적다. 증상은 단지 주위조직에 대한 압박정도이다. ii)악성종양: 침윤과 전이가 있고 퇴화도가 높은 세포로 구성됨. 기원세포가 상피조직일 경우 암종, 비상피성일 경우 육종으로 나누기도 한다. 치료에 잘 반응하지 않고, 재발을 잘 하며, 생존율이 낮다. 흔히 말하는 “암”을 의미한다. B. 조직학적 특징에 따라 샘종, 지방종, 근종 등으로 나누기도 한다. (2) 병리조직학적 특징 A. 육안적 소견 덩어리를 형성하기도 하고 정상조직에 스며들듯이 판상구조를 이루기도 하는 등 다양한 형태를 보인다. 양성의 경우 피막을 가진 경우가 많고 악성의 경우 없는 경우가 많다. 육안소견에 따라 다음과 같이 나눈다. 낭성, 융기성, 괴사성, 폴립모양, 궤양형 등이 있다. 또는 세포의 크기와 모양이 비정상적인 형태로 변화한다. 핵의 극성이 사라지고 핵의 염색성이 짙어진다. 세포질의 염색성도 변화하며 세포들간의 세포주기가 매우 다양해져 많은 세포분열을 보인다. 이러한 일련의 변화를 역형성이라 한다. 역형성의 정도에 따라 조직학적 등급을 나눈다. 또한 각 종양에 따라 각기 다른 병리조직학적 명칭을 붙인다. |
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| CT | calcitonin; calf testis; cardiac tamponade; cardiothoracic [ratio]; carotid tracing; carpal tunnel; ... |
|---|---|
| MC | mass casualties; mast cell; Master of Surgery [Lat. Magister Chirurgiae]; maximum concentration; Med... |
| MEN | Multiple Endocrine Neoplasia ; AD Trait 1. MEN Type I(= Wermer Syndro... |
| JGCT | juvenile granulosa cell tumor; juxtaglomerular cell tumor |
| TC | target cell; taurocholate; temperature compensation; teratocarcinoma; tertiary cleavage; tetracyclin... |
| granular layer of cerebellum | The deepest of the three layers of the cortex; it contains large numbers of granule cells, the dendrites of which synapse with incoming mossy fibres in cerebellar glomeruli. Thin, unmyelinated axons of granule cells ascend perpendicularly into the molecular layer in which they bifurcate into fibres coursing parallel to the long axis of the cerebellar folia. Parallel fibres form numerous synapses with the dendrites of Purkinje cells, basket cells, and stellate cells. Synonym: stratum granulosum cerebelli, granular layer of cerebellar cortex. (05 Mar 2000) |
|---|---|
| granular layer of epidermis | A layer of somewhat flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum and deeply to the stratum corneum. Synonym: stratum granulosum epidermidis. (05 Mar 2000) |
| granular layers of cerebral cortex | Layers 2 (outer) and 4 (inner) of the cortex cerebri. (05 Mar 2000) |
| granular layers of retina | The outer nuclear layer, layer 4, of the retina, neuroepithelial layer of retina, and the inner layer, layer 6, of the retina, ganglionic layer of retina. Synonym: granular layers of retina, stratum nucleare externum et internum retinae. (05 Mar 2000) |
| granular leukoblast | An obsolete term for promyelocyte. (05 Mar 2000) |
| granular leukocyte | Any one of the polymorphonuclear leukocyte's, especially a neutrophilic leukocyte. See: granulocyte, basophilic leukocyte, eosinophilic leukocyte. (05 Mar 2000) |
| granular lids | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| granular ophthalmia | <ophthalmology> A chronic infectious disease of the conjunctiva and cornea, producing photophobia, pain, lacrimation and blindness. It is one of the oldest infectious diseases known to mankind, and dates back several thousand years with first documentation as early as the pharaonic era in Egypt. The disease is associated with poor socioeconomic conditions in general: with overcrowding, poor personal and environmental hygiene and, in particular, with very limited access to water and sanitation. Trachoma has been eliminated as a blinding disease from several previously hyperendemic countries and regions, both through significant improvements in the socioeconomic status of populations and through specific control efforts. Despite these successes, in many least developed countries of the world blinding trachoma continues to be an important public health problem. In some of the countries where trachoma was once hyperendemic, there remain residual pockets of blinding trachoma and complications, such as inturned eyelashes (trichiasis), which require eyelid surgery. Today, the disease is found mainly in poor rural areas, including parts of central and south America, most African countries and some countries in the Eastern Mediterranean. Trachoma is still endemic in several Asian countries, but there is a lack of updated information from some major populations, e.g. In India and China. The organism that causes this disease is Chlamydia trachomatis; a microorganism resembling both bacteria and viruses, which spreads through contact with eye discharge from the infected person (on towels, handkerchiefs, fingers, etc.) and through transmission by eye-seeking flies. Chlamydia trachomatis provokes an inflammatory reaction in the eye with formation of follicles in the conjunctiva. After years of repeated infections, the inside of the eyelids may be scarred so severely that the eyelid turns inwards with eyelashes rubbing on the eyeball. If untreated, this condition leads to blindness. The World Health Organization is working towards global elimination of trachoma, which is responsible, at present, for at least 15% of the world's blindness. Worldwide, there are about 6 million people largely irreversibly blinded by trachoma, and an estimated 146 million cases of active disease in need of treatment, if blindness is to be prevented. International efforts to eliminate trachoma as a blinding disease will be based on a combination of interventions known by the acronym "SAFE", which stands for Surgery for trichiasis (inturned eyelashes), Antibiotics, Facial cleanliness and Environmental improvement. These interventions will be community-targeted and will seek community involvement through the primary health care approach. Origin: Gr. Trachoma = roughness (07 May 1998) |
| granular pits | Pits on the inner surface of the skull, along the course of the superior sagittal sinus, in which are lodged the arachnoidal granulations. Synonym: foveolae granulares, pacchionian depressions. (05 Mar 2000) |
| granular pneumonocytes | Cuboidal cell's connected with the squamous pulmonary alveolar cell's and having in their cytoplasm lamellated bodies (cytosomes) that represent the source of the surfactant that coats the alveoli. Synonym: granular pneumonocytes, type II cells. (05 Mar 2000) |
| granular trachoma | <ophthalmology> The ordinary form of trachoma marked by the presence of granulations on the conjunctiva. Synonym: granular trachoma. (05 Mar 2000) |
| granular urethritis | <urology> Chronic urethritis with nodular lymphocytic infiltrations in the mucosa. Synonym: granular urethritis. (05 Mar 2000) |
| granular vaginitis | A condition of cattle manifested by the appearance of small, spherical, transparent nodules in the mucosa of the vagina of cows and of the penis of bulls; the mucosa is reddened and a mucopurulent exudate appears on the affected surfaces; it is a non specific hyperplastic response of the lymphatic tissue of these areas to an irritant or an antigen. (05 Mar 2000) |
| Tomes' granular layer | <dentistry> A thin layer of dentin adjacent to the cementum, appearing granular in ground sections; the granules are small uncalcified spaces. (05 Mar 2000) |
| T-cell-rich, B-cell lymphoma | <tumour> A B-cell lymphoma in which more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component. See: adult T-cell lymphoma. (05 Mar 2000) |