| gold sodium thiomalate | <chemical> A variable mixture of the mono- and disodium salts of gold thiomalic acid used mainly for its anti-inflammatory action in the treatment of rheumatoid arthritis. It is most effective in active progressive rheumatoid arthritis and of little or no value in the presence of extensive deformities or in the treatment of other forms of arthritis. Pharmacological action: antirheumatic agents, gold. Chemical name: Butanedioic acid, mercapto-, monogold(1+) sodium salt (12 Dec 1998) |
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| gold sodium thiosulfate | <chemical> An antirheumatic agent with the same actions and uses as gold sodium thiomalate. Pharmacological action: antirheumatic agents, gold. Chemical name: Aurate(3-), bis(monothiosulfato(2-)-O,S)-, trisodium, (T-4)- (12 Dec 1998) |
| gold sol test | An obsolete, non-specific test for altered proteins in spinal fluid. As originally used by Lange in 1912, the test was thought to be specific for neurosyphilis; however, this proved to be incorrect. Dilutions of spinal fluid are made in saline and to these a colloidal gold solution is added; if altered proteins are present, there is a colour change or precipitate formed. at present, its chief use is to demonstrate cerebrospinal fluid protein abnormalities in multiple sclerosis. Synonym: gold sol test, Zsigmondy's test. (05 Mar 2000) |
| gold standard | Term used to describe a method or procedure that is widely recognised as the best available. Origin: jargon (05 Mar 2000) |
| gold thioglucose | <chemical> (1-thio-d-glucopyranosato)gold. A thioglucose derivative used as an antirheumatic and experimentally to produce obesity in animals. Pharmacological action: antirheumatic agents, gold. Chemical name: Gold, (1-thio-D-glucopyranosato-O2,S1)- (12 Dec 1998) |
| cohesive gold | Nearly pure gold so treated as to be free of adsorbed surface gases and impurities so that it will weld under pressure at room temperature; in dentistry, used as a restorative material placed directly into a prepared cavity and welded by pressure. (05 Mar 2000) |
| colloidal gold reaction | A test (now obsolete) based on precipitation of cerebrospinal fluid protein when mixed with colloidal gold. Abnormalities in this reaction were observed in patients with syphilis, multiple sclerosis, poliomyelitis, and encephalitis. (05 Mar 2000) |
| colloidal radioactive gold | A radioactive isotope of gold emitting negative beta particles and gamma radiation, with a half-life of 2.7 days; formerly used for irradiation of closed serous cavities in the palliative treatment of ascites and pleural effusion due to metastatic malignancies, and for liver scans. Synonym: 198Au colloid, colloidal radioactive gold. (05 Mar 2000) |
| powdered gold | Gold formed by atomizing or by chemical precipitation, lightly precondensed, and wrapped with gold foil so as to form pellets. (05 Mar 2000) |
| noncohesive gold | Gold that will not weld because gases adsorb to the surface; some forms may be made cohesive by heat treatment; in dentistry, used as a direct filling material. (05 Mar 2000) |
| acetone compound | <biochemistry> Any of the three compounds created by acetyl coenzyme A (acetoacetate, hydroxybutyrate, and acetone) which are water-soluble cellular fuels normally exported by the liver. They can build up in the blood and body tissues because of starvation, untreated diabetes mellitus, or other disorders that interfere with carbohydrate metabolism. The body rids itself of ketones mainly through urine, but it rids itself of acetone through the lungs, which gives the breath a characteristic fruity odour. If ketones build up in the body long enough, they cause serious illness and coma (see ketoacidosis.) (09 Oct 1997) |
| acyclic compound | An organic compound in which the chain does not form a ring. Synonym: aliphatic compound, open chain compound. (05 Mar 2000) |
| addition compound | Strictly, a complex of two or more complete molecules in which each preserves its fundamental structure and no covalent bonds are made or broken (e.g., hydrates of salts, adducts), loosely, association of acids with basic organic compound's (e.g., amines with HCl), more loosely, addition of two molecules without loss of any atom, but forming new covalent bonds (e.g., CH2==CH2 + Br2 → BrCH2-CH2Br). (05 Mar 2000) |
| aliphatic compound | An organic compound in which the chain does not form a ring. Synonym: aliphatic compound, open chain compound. (05 Mar 2000) |
| APC compound | An analgesic tablet drug combination containing aspirin, phenacetin and caffeine. Very widely used in the 1940's through 1960's; original constituents of popular over-the-counter pain remedies. Use currently much diminished due to concerns about potential renal injury due to the phenacetin. (05 Mar 2000) |