| nodular leprosy | A benign, stable, and resistant form of the disease in which the lepromin reaction is strongly positive and in which the lesions are erythematous, insensitive, infiltrated plaques with clear-cut edges. Synonym: nodular leprosy, smooth leprosy. (05 Mar 2000) |
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| nodular lymphoma | <tumour> A malignant lymphoma arising from lymphoid follicular B-cells which may be small or large, growing in a nodular pattern. Synonym: follicular lymphoma, giant follicular lymphoblastoma. (05 Mar 2000) |
| nodular melanoma | <tumour> Primary cutaneous melanoma characterised by dermal invasion extending to the lateral margins of epidermal involvement or ulceration. (05 Mar 2000) |
| nodular nonsuppurative panniculitis | relapsing febrile nodular nonsuppurative panniculitis |
| nodular non-X histiocytosis | A rare recurring generalised eruption in adults of flesh coloured or erythematous papules remaining localised to the skin and consisting of dermal nodules of mononuclear histiocytes that do not stain for lipid. Synonym: nodular non-X histiocytosis. (05 Mar 2000) |
| nodular opacity | A solitary, round, circumscribed shadow found in the lung on chest radiograph; causes include granuloma, primary or metastatic carcinoma, benign tumour, vascular malformation. Synonym: coin lesion of lungs. (05 Mar 2000) |
| nodular regenerative hyperplasia | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| nodular scleritis | Firm, immobile, single or multiple areas of localised scleritis. (05 Mar 2000) |
| nodular sclerosis | <cardiology, pathology> The progressive narrowing and hardening of the arteries over time. This is known to occur to some degree with aging, but other risk factors that accelerate this process have been identified. These factors include: high cholesterol, high blood pressure, smoking, diabetes and family history for atherosclerotic disease. (27 Sep 1997) |
| nodular subepidermal fibrosis | A slowly growing benign skin nodule consisting of poorly demarcated cellular fibrous tissue enclosing collapsed capillaries with scattered haemosiderin-pigmented and lipid macrophages. They are common, usually about 1 cm in diameter and occur in the dermis. Simple excision is always curative. (12 Dec 1998) |
| nodular syphilid | Origin: NL. So called from its gummy contents See Gum. <medicine> A kind of soft tumour, usually of syphilitic origin. Source: Websters Dictionary (01 Mar 1998) |
| nodular transformation of the liver | A rare condition in which nodules of hyperplastic hepatocytes develop without fibrosis or general loss of lobular architecture. Synonym: nodular regenerative hyperplasia. (05 Mar 2000) |
| nodular tuberculid | A type of panniculitis characterised histologically by the presence of granulomas, vasculitis, and necrosis. It is traditionally considered to be the tuberculous counterpart of nodular vasculitis, but is now known to occur without tuberculous precedent. It is seen most commonly in adolescent and menopausal women, is initiated or exacerbated by cold weather, and typically presents as one or more recurrent erythrocyanotic nodules or plaques on the calves. The nodules may progress to form indurations, ulcerations, and scars. (12 Dec 1998) |
| nodular vasculitis | Chronic or recurrent nodular lesions of subcutaneous tissue, especially of the legs of older women, with lobular panniculitis, granulomatous inflammation with multinucleated giant cells, focal necrosis, and obliterative inflammation of the small blood vessels, resembling erythema induratum but without evidence of associated tuberculosis. (05 Mar 2000) |
| toxic nodular goitre | <endocrinology> An enlarged thyroid gland which contains nodules which release excess thyroid hormone. This condition usually arises from long-standing simple goitre in the elderly. Symptoms of hyperthyroidism result. (12 Jan 1998) |