| glycine-succinate cycle | A series of metabolic steps in which glycine is condensed with succinyl-CoA and is then oxidised to CO2 and H2O with regeneration of the succinyl-CoA; important in the synthesis of d-aminolevulinic acid and in the metabolism of red blood cells. Synonym: Shemin cycle. (05 Mar 2000) |
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| glycine synthase | A complex of several proteins that catalyze the reversible reaction of glycine with tetrahydrofolate to produce CO2, NH3, and N5,N10-methylenetetrahydrofolate; a deficiency of this enzyme (or one of its subunits) will result in nonketotic hyperglycinaemia. Synonym: glycine synthase. (05 Mar 2000) |
| glycine transamidinase | <enzyme> An enzyme catalyzing the transfer of an amidine group from l-arginine to glycine, forming guanidinoacetate and l-ornithine; an important reaction in creatine synthesis; it can also act on canavanine. Synonym: glycine transamidinase. (05 Mar 2000) |
| glycine-trna ligase | <enzyme> An enzyme that activates glycine with its specific transfer RNA. Chemical name: Glycine:tRNA(Gly) ligase (AMP-forming) Registry number: EC 6.1.1.14 (12 Dec 1998) |
| abnormal cleavage of cardiac valve | Congenital malformation of a valve leaflet with a defect extending from the free margin. (05 Mar 2000) |
| adequal cleavage | Cleavage resulting in the formation of blastomeres of approximately equal size. (05 Mar 2000) |
| anterior chamber cleavage syndrome | <syndrome> A congenital disorder originating from faulty separation of embryonic structures; it results in bilateral central corneal opacities, with an anterior ring attachment of the iridic pupillary border and anterior polar cataracts; associated with short-limbed dwarfism; autosomal dominant inheritance. See: iridocorneal endothelial syndrome. Synonym: Peters' anomaly. (05 Mar 2000) |
| beta-carotene cleavage enzyme | <enzyme> An enzyme catalyzing the reaction of beta-carotene plus O2 producing two retinals. Synonym: beta-carotene cleavage enzyme, carotenase, carotinase. (05 Mar 2000) |
| meridional cleavage | Cleavage in a plane through the axis of the zygote. (05 Mar 2000) |
| meroblastic cleavage | Incomplete separation of the blastomeres, with the divisions being limited to the nonyolked portion of the egg. Synonym: incomplete cleavage. (05 Mar 2000) |
| citrate cleavage enzyme | ATP citrate (pro-3S)-lyase |
| phosphoroclastic cleavage | <biochemistry> This reaction is an analogue to hydrolysis, except here a molecule is cleaved with phosphate as the attacking group. (09 Oct 1997) |
| cleavage | <cell biology> The early divisions of the fertilized egg to form blastomeres. The cleavage pattern is radial in some phyla, spiral in others. (18 Nov 1997) |
| cleavage cavity | The cavity in the blastula of a developing embryo. Synonym: blastocoele, cleavage cavity, segmentation cavity. Origin: blasto-+ G. Koilos, hollow (05 Mar 2000) |
| cleavage cell | One of the cells produced as the result of cell division, cleavage, in the fertilized egg. (18 Nov 1997) |