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PTI pancreatic trypsin inhibitor; persistent tolerant infection; Pictorial Test of Intelligence; placent...
STI Scientific and Technical Information; serum trypsin inhibitor; soybean trypsin inhibitor; systolic t...
OMI Oocyte Maturation Inhibitor
ACEI angiotensin-converting enzyme inhibitor
ACI acceleration index; acoustic comfort index; acute cardiac ischemia; acute coronary infarction; acute...
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PI 1-protease inhibitor
PI 1-proteinase inhibitor
PIC 2-plasmin inhibitor plasmin complex
ACE-I ACE inhibitor
ACPI Acid cysteine proteinase inhibitor
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oligo-1,6-glucosidase <enzyme> An enzyme that catalyses the endohydrolysis of 1,6-alpha-glucosidic linkages in isomaltose and dextrins produced from starch and glycogen by alpha-amylase.
Chemical name: Dextrin 6-alpha-D-glucanohydrolase
Registry number: EC 3.2.1.10
(12 Dec 1998)
oligo-a1,6-glucosidase A glucanohydrolase cleaving alpha-1,6 links in isomaltose and dextrins produced from starch and glycogen by alpha-amylase; secreted into the duodenum; a deficiency of this enzyme leads to defects in intestinal digestion of limit dextrins.
See: sucrose alpha-d-glucohydrolase.
Synonym: isomaltase, limit dextrinase.
(05 Mar 2000)
exo-1,4-alpha-d-glucosidase A hydrolase removing terminal alpha-1,4-linked d-glucose residues from nonreducing ends of chains, with release of beta-d-glucose.
Synonym: acid maltase, amyloglucosidase, gamma-amylase, glucoamylase.
(05 Mar 2000)
4-methylumbelliferyl-beta-glucosidase <enzyme> Aspect of EC 3.2.1.21
Registry number: EC 3.2.1.-
(26 Jun 1999)
4-nitrophenyl-alpha-glucosidase <enzyme> Involved in glycoprotein precessing; cleaves 1-3 linked glucose residues
Registry number: EC 3.2.1.-
Synonym: pnp-alpha-d-glucosidase, para-nitrophenyl-alpha-glucosidase, glucosidase II
(26 Jun 1999)
6-ethanoylamino-4-methylumbelliferyl-beta-glucosidase <enzyme> A soluble lysosomal enzyme with a discrete isoelectric point of about 5.0; hydrolyzes 6-ethanoylamino-4-methylumbelliferyl-beta-d-glucoside
Registry number: EC 3.2.1.-
Synonym: emglc-ase
(26 Jun 1999)
6-phospho-alpha-glucosidase <enzyme> Hydrolyzes maltose-6'-phosphate to glucose-6-phosphate
Registry number: EC 3.2.1.-
Synonym: 6-phosphoryl-o-alpha-d-glucopyranosyl - 6-phosphoglucohydrolase, maltose-6'-phosphate glucosidase, maltose 6-phosphate hydrolase, malh gene product
(26 Jun 1999)
6-phospho-beta-glucosidase <enzyme> Catalyses the conversion of 6-phospho-beta-d-glucosyl-(1,4)-d-glucose and h2o to d-glucose-6-phosphate and d-glucose; do not confuse with bgla gene product from rhodothermus which catalyses the reaction of EC 3.2.1.39 (endo-1,3-beta-glucanase)
Registry number: EC 3.2.1.86
Synonym: bgla gene product, bglh gene product, glvg gene product
(26 Jun 1999)
furostanol glycoside 26-O-beta-glucosidase <enzyme> From costus speciosus rhizomes; specifically cleaves the c-26-bound glucose moiety of furostanol glycosides
Registry number: EC 3.2.1.-
Synonym: f26g enzyme
(26 Jun 1999)
a1-trypsin inhibitor A glycoprotein that is the major protease inhibitor of human serum, is synthesised in the liver, and is genetically polymorphic due to the presence of over 20 alleles; individuals appropriately homozygous are deficient in a1-trypsin and are predisposed to pulmonary emphysema and juvenile hepatic cirrhosis because of alterations in the amino acid and sialic acid components of the glycoprotein. A1-Antitrypsin also inhibits thrombin.
Synonym: a1-trypsin inhibitor, human a1-proteinase inhibitor.
(05 Mar 2000)
ACE inhibitor <pharmacology> A group of antihypertensive medications that work by inhibiting an enzyme (angiotensin-converting enzyme) that is important in the regulation of blood pressure.
Studies have also indicated that it may help prevent or slow the progression of kidney disease in patients with diabetes.
Examples include: captopril, ramipril, enalapril, losartan potassium, bepridil and lisinopril.
(12 Mar 1998)
aldose reductase inhibitor <pharmacology> A class of drugs being studied as a way to prevent eye and nerve damage in people with diabetes.
Aldose reductase is an enzyme that is normally present in the eye and in many other parts of the body. It helps change glucose (sugar) into a sugar alcohol called sorbitol. Too much sorbitol trapped in eye and nerve cells can damage these cells, leading to retinopathy and neuropathy.
Drugs that prevent or slow (inhibit) the action of aldose reductase are being studied as a way to prevent or delay these complications of diabetes.
(09 Oct 1997)
angiotensin-converting enzyme inhibitor <pharmacology> A class of drugs used in the treatment of hypertension and heart failure.
They exert their haemodynamic effect mainly by inhibiting the renin-angiotensin system and produce a reduction of peripheral arterial resistance. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
(14 Aug 2000)
aromatase inhibitor Drugs, such as aminoglutethimide, that inhibit aromatase, an enzyme used in the synthesis of oestrogens.
(05 Mar 2000)
beta-lactamase inhibitor <pharmacology> Drugs such as clavulanic acid, which are used to inhibit bacterial beta-lactamases; often used with a penicillin or cephalosporin to overcome drug resistance.
(05 Mar 2000)
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