| 영문 | risk factor | 한글 | 위험인자 |
|---|---|---|---|
| 설명 | 국제방사선방호위원회(ICRP)가 1977년 권고에서 방사선방호의 목적으로 채택한 지수로, 단위선량(1 Sv)당 확률적 영향의 발생확률을 추정하여 나타낸 것이다. 생식선 선량에 대한 유전적영향의 발생률(4×10－3/Sv)이나 적색골수선량에 대한 백혈병 발생률(2×10－3/Sv)등 외에 뼈, 허파, 갑상샘, 젖샘, 기타 조직의 위험지수를 측정하여, 확률적 영향의 전신에 있어서 치사위험지수의 합계를 16.5×10－3/Sv로 하였다. 그후 ICRP는 1990년 권고에서 대상이 되는 조직과 장기를 추가하고, 수치 개정을 하면서 명칭도 각목적확률지수라고하였다. 이 권고에 의하면, 치사적 확률적 영향의 확률지수의 합계는, 일반인에 있어 60.0×10－3/Sv이다. |
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| PAF | paroxysmal atrial fibrillation; peroxisomal assembly factor; phosphodiesterase-activating factor; pl... |
|---|---|
| SF | Sabin-Feldman [test]; safety factor; salt-free; scarlet fever; screen film; seminal fluid; serosal f... |
| TF | free thyroxine; tactile fremitus; tail flick [reflex]; temperature factor; testicular feminization; ... |
| AITT | arginine insulin tolerance test; augmented insulin tolerance test |
| ATT | arginine tolerance test; aspirin tolerance time |
| species tolerance | The insensitivity to a particular drug exhibited by a particular species. (05 Mar 2000) |
|---|---|
| split tolerance | Modification of an immune response to an antigen after prior exposure to that antigen. Synonym: split tolerance. (05 Mar 2000) |
| nonresponder tolerance | Lack of immune response to antigen. Theories of tolerance induction include clonal deletion and clonal anergy. In clonal deletion, the actual clone of cells is eliminated whereas in clonal anergy the cells are present but nonfunctional. Synonym: immunological tolerance, immunotolerance, nonresponder tolerance. (05 Mar 2000) |
| drug tolerance | Progressive diminution of the susceptibility of a human or animal to the effects of a drug, resulting from its continued administration. It should be differentiated from drug resistance wherein a human, animal, disease, or tissue fails to respond to the intended effectiveness of a chemical or drug. (12 Dec 1998) |
| immune tolerance | The specific failure of a normally responsive individual to make an immune response to a known antigen. It results from previous contact with the antigen by an immunologically immature individual (foetus or neonate) or by an adult exposed to extreme high-dose or low-dose antigen, or by exposure to radiation, antimetabolites, antilymphocytic serum, etc. (12 Dec 1998) |
| immunological tolerance | <immunology> Specific unresponsiveness to antigen. Self tolerance is a process occurring normally early in life due to suppression of self reactive lymphocyte clones. Tolerance to foreign antigens can be induced in adult life by exposure to antigens under conditions in which specific clones are suppressed. Note that tolerance is not the same as immunological unresponsiveness, since the latter may be very non-specific as in immunodeficiency states. (18 Nov 1997) |
| immunologic high dose tolerance | Induction of tolerance by exposure to large amounts of protein antigens. (05 Mar 2000) |
| immunologic tolerance | Lack of immune response to antigen. Theories of tolerance induction include clonal deletion and clonal anergy. In clonal deletion, the actual clone of cells is eliminated whereas in clonal anergy the cells are present but nonfunctional. Synonym: immunological tolerance, immunotolerance, nonresponder tolerance. (05 Mar 2000) |
| individual tolerance | Tolerance to a drug that the person has never received before. (05 Mar 2000) |
| oral lactose tolerance test | A test for lactose deficiency; the plasma glucose response to an oral lactose load is measured as in the (oral) glucose tolerance test. (05 Mar 2000) |
| tolerance | 1. The ability to endure unusually large doses of a drug or toxin. 2. Acquired drug tolerance, a decreasing response to repeated constant doses of a drug or the need for increasing doses to maintain a constant response. Origin: L. Tolerantia (18 Nov 1997) |
| tolerance dose | The largest dose of a remedy that can be accepted without the production of injurious symptoms. (05 Mar 2000) |
| exercise tolerance | The exercise capacity of an individual as measured by endurance (maximal exercise duration and/or maximal attained work load) during an exercise test. (12 Dec 1998) |
| frustration tolerance | The level of an individual's ability to withstand frustration without developing inadequate modes of response, such as "going to pieces" emotionally. (05 Mar 2000) |
| activated glucose | A nucleoside diphosphoglucose such as UDP glucose. (05 Mar 2000) |