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glomerulonephritis, membranoproliferative Chronic glomerulonephritis characterised histologically by proliferation of mesangial cells, increase in the mesangial matrix, and a thickening of the glomerular capillary walls. The wall thickening is sometimes said to be a result of the interposition of mesangial cytoplasm or matrix between the basement membrane and the endothelium of the capillary wall. It is often divided into types I and II, and sometimes III. Pathogenesis is not well understood, but some types are thought to involve the immune system, with the complement system, in particular, being implicated.
(12 Dec 1998)
glomerulonephritis, membranous A disease of the glomerulus manifested clinically by proteinuria, and sometimes by other features of the nephrotic syndrome. It is histologically characterised by deposits in the glomerular capillary wall between the epithelial cell and the basement membrane and a thickening of the membrane. Also characteristic are outward projections of the membrane between the epithelial deposits in the form of "spikes". There is some agreement that the deposits are antigen-antibody complexes.
(12 Dec 1998)
glomerulopathy Glomerular disease of any type.
Origin: Glomerulus + G. Pathos, suffering
(05 Mar 2000)
glomerulosa cell A cell of the zona glomerulosa of the adrenal cortex that is the source of aldosterone; the cell's are arranged in spherical or oval groups.
(05 Mar 2000)
glomerulosclerosis Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes.
Synonym: glomerular sclerosis.
Origin: Glomerulus + G. Sklerosis, hardness
(05 Mar 2000)
glomerulosclerosis, focal Glomerular disease characterised by focal and segmental areas of glomerular sclerosis, usually commencing in the juxtamedullary glomeruli and gradually spreading to involve other parts of the kidney, with eventual kidney failure.
(12 Dec 1998)
glomerulose <nephrology> Pertaining to or of the nature of a glomerulus, especially a renal glomerulus.
(14 Oct 1997)
glomerulus <anatomy, nephrology> One of the structures which comprise the nephron (functional unit) in the kidney. The glomerulus is composed of capillary blood vessels which are actively involved in the filtration of the blood.
(27 Sep 1997)
glomerulus of mesonephros One of the tufts of capillary vessels within the mesonephros derived from a lateral branch of the primary aorta; each glomerulus is connected to a tubule.
(05 Mar 2000)
glomerulus of pronephros One of the tufts of capillary vessels in the pronephros derived from a lateral branch of the aorta.
(05 Mar 2000)
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